Plasmocytoma, multiple myeloma and plasma cell neoplasms in orofacial region

Zajko, J; Czako, L; Galis, B

doi:10.4149/bll_2016_083

Cited by 6 publications

(7 citation statements)

References 7 publications

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“…No MM há disseminação dessa desordem. 10 O MM é uma das neoplasias hematológicas mais comuns, com leve predileção pelo sexo masculino. A maioria dos casos acontece entre a 50 e 80 anos, com média de 60 anos, mas a manifestação em pacientes jovens é relatada.…”

Section: Discussão E Conclusõesunclassified

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Recidiva de mieloma múltiplo em mandíbula mimetizando lesão endodôntica: relato de caso

Domingos¹,

Rocha²,

Moreira³

et al. 2020

j.rpemd

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On-line a 21 de setembro de 2020 O mieloma múltiplo é uma neoplasia maligna disseminada que afeta os plasmócitos. O envolvimento da região maxilofacial é incomum, mas pode envolver os ápices dentários. O objetivo deste trabalho é descrever um caso clínico de mieloma múltiplo recidivante que mimetizou lesão endodôntica. Doente, 75 anos, sexo feminino, procurou atendimento odontológico de urgência devido a aumento de volume na mandíbula, na região dos dentes 44 e 45, semelhante a celulite odontogénica. Foi realizado o tratamento odontológico de urgência do dente 45, seguido de posterior tomografia computadorizada e biópsia incisional, devido a diagnóstico pregresso de mieloma múltiplo. O exame de imagem revelou lesão osteolítica, envolvendo o ápice dos dentes 44 e 45. O exame histológico evidenciou proliferação de células com morfologia plasmocitóide e atipia, que invadiam o tecido conjuntivo, confirmando o diagnóstico de mieloma múltiplo recidivante. A paciente foi encaminhada a tratamento oncológico e encontra-se estável até hoje. (Rev Port Estomatol Med Dent Cir Maxilofac.

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Section: Discussão E Conclusõesunclassified

“…Todavia, a odontalgia causada pelo MM é bastante incomum, sendo pouco relatada na literatura. 6,10,12,13 A abordagem terapêutica para o MM depende da idade do paciente, saúde geral e comorbidades relacionadas. O tratamento do MM envolve radioterapia, quimioterapia, esteróides e transplante autólogo de células tronco.…”

Section: Discussão E Conclusõesunclassified

Recidiva de mieloma múltiplo em mandíbula mimetizando lesão endodôntica: relato de caso

Domingos¹,

Rocha²,

Moreira³

et al. 2020

j.rpemd

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“…Plasmocytoma is a rare malignant tumor of differentiated B cells in the bone marrow [1][2][3][4]. It represents 1% of all types of malignant tumors and a little more than 3-5% of plasma cell neoplasms.…”

Section: Introductionmentioning

confidence: 99%

“…They are divided into three types. Solitary bone plasmacytoma, extramedullary plasmacytoma and its disseminated form also called multiple myeloma [1]. Primary cranioencephalic plasmacytoma is very rare and it may be a plasmacytoma of the skull (bone form) or a dural plasmacytoma (non-bone form) [3].…”

Section: Introductionmentioning

confidence: 99%

Solitary Bone Plasmacytoma in Skull, with Regards to a Case

Armendáriz

2020

OAJNN

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“…Dear Editor-in-Chief, As practising specialists in the fi elds of oral medicine and maxillofacial surgery we would like to comment on the article published in issue 7/2016 of Bratislava Medical Journal from Zajko J et al (1). In our opinion it is extremely needed to report about lesser-known diseases occurring possibly in the orofacial region.…”

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confidence: 98%

Letter to the Editor

Stanko¹,

Sobolikova²,

Manesh³

et al. 2017

BLL

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Dear Editor-in-Chief, As practising specialists in the fi elds of oral medicine and maxillofacial surgery we would like to comment on the article published in issue 7/2016 of Bratislava Medical Journal from Zajko J et al (1). In our opinion it is extremely needed to report about lesser-known diseases occurring possibly in the orofacial region. In earlier as well as recent literature only few articles exist dealing with case reports of plasmocytoma (2, 3, 9), mostly of the extramedullary type in soft tissue emphasizing the clinical manifestation (4, 5) or rare combination with other malignancies (6). Epidemiologic evidence of the outcomes based on literature study is still controversial although radical surgery in combination with postoperative irradiation and chemotherapy provides acceptable results (7, 8,4).The authors stated that researchers still do not know exactly the causes of plasmocytoma but there are some factors that could be contributing to this disease. We would like to know whether the authors have noticed any factors of probable combination of factors in their cases? As this is a very rare condition with incidence of 3-4 per 100,000 inhabitants, would it not be even better to include the data from other specialists to create a larger study group for the analysis? The article reveals that all the patients were diagnosed at presentation with tumour-like lesions and had biochemically negative examinations. We would appreciate greatly any advice as e.g. on clinical symptomatology or radiological differential diagnosis that could enable general dentists to state an earlier diagnosis of plasmocytoma in the oral cavity.Despite our questions we would like to express our acknowledgement of the article and reported case with solitary plasmocytoma in the TMJ region. To our best knowledge, this is the fi rst case reported in this specifi c location.

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Plasmocytoma, multiple myeloma and plasma cell neoplasms in orofacial region

Abstract: A neoplastic proliferation of B cell lymphocyte is called plasma cell neoplasms, results from malignant plasma cells transformation in bone marrow. The authors present a clinical study and overview of this pathology in maxillofacial region for six years (Tab. 2, Ref. 14).

Cited by 6 publications

References 7 publications

Recidiva de mieloma múltiplo em mandíbula mimetizando lesão endodôntica: relato de caso

Recidiva de mieloma múltiplo em mandíbula mimetizando lesão endodôntica: relato de caso

Solitary Bone Plasmacytoma in Skull, with Regards to a Case

Letter to the Editor

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