Pleomorphic Carcinoma of the Larynx

Outcomes and patterns of failure of sarcomatoid carcinoma of the larynx: The Mayo Clinic experience

“…It is most frequently found in the glottic larynx, and it accounts for <1.5% of all malignant laryngeal tumors . Since the first recognition of this entity in 1864, different terms have been used to describe it, such as carcinosarcoma, pseudosarcoma, sarcomatoid carcinoma, pleomorphic carcinoma, and spindle cell carcinoma . The differing nomenclature stems from the tumor's unclear etiology.…”

“…[1][2][3] Since the first recognition of this entity in 1864, different terms have been used to describe it, such as carcinosarcoma, 4,5 pseudosarcoma, 6 sarcomatoid carcinoma, pleomorphic carcinoma, and spindle cell carcinoma. [6][7][8][9][10][11] The differing nomenclature stems from the tumor's unclear etiology. Over the years, several theories have been proposed regarding the tumor's origin.…”

Spindle cell squamous carcinoma of the larynx

“…Prior to this report, probable cases of spindle cell squamous carcinoma of the larynx had been described by Figi (1933); Saphir and Vass (1938); Frank and Lev (1940) and Brooks (1943). Later the neoplasm was reported by other authors (Baker, 1959;Grigg et al, 1961;Legier, 1962;Sherwin, et al, 1963;Appelman and Oberman, 1965;De Brux et al, 1966;Filotico and Trabucco, 1966;Himalstein and Humphrey, 1968;Davies, 1969;Lichtigerefa/., 1970;Staley et al, 1971;Andrews and Oliver, 1972;Cachin, etal, 1972;Goellner, etal, 1973;Hyams, 1975;Randall era/., 1975;Friedelef al., 1976;Kleinsasser and Glanz, 1978;Lambert et al, 1980;Broich, 1981;Fechner and McCarthy, 1981;Leventon and Evans, 1981;Silvagnief al., 1981;Batsakis etal., 1982;Deshotelse?a/., 1982;Giordano et al, 1983;Spencer etal., 1983).…”

The Early Diagnosis of Carcinoma of the Larynx

“…Other malignant lesions do occur in the larynx. These include adenocarcinoma (Toomey, 1967) ; fibrosarcoma (Johnston, 1957) and pleomorphic carcinoma (Himalstein and Humphrey, 1968). Chondrosarcoma also occurs.…”