Po317 Are There Any Correlations Between Ratio LDL-C/HDL-C and Lipoprotein(a) With Insulin Resistance in Type 2 Diabetes Patients With Abdominal Obesity?

Abstract

Background: Cross-sectional studies have reported risk factors and prevalence of type 2 diabetes. Incidence rates and risk factor for type 2 diabetes in Chinese populations are not well known. The aim of this study was to evaluate the impact of weight change and other risk factors on incident type 2 diabetes in Qingdao, China. Method: The population-based prospective cohort study was based on subjects aged 35-74 years who participated in Qingdao Diabetes Survey in 2006. The subjects were free of diabetes at baseline. A total of 1,294 subjects attended the follow up survey between 2009 and 2011. Diabetes diagnosis was classified according to the World Health Organization and International Diabetes Federation 2006 criteria. A logistic regression was built using the backward stepwise selection to assess effect of the risk factors on incident type 2 diabetes.Result: During a 4-year follow up, 120 cases of incident type 2 diabetes was identified, with cumulative incidence of diabetes of 11.8%. Participant who developed type 2 diabetes were significantly older, have significantly higher age-adjusted BMI, waist circumference, systolic blood pressure and total cholesterol than subjects who remained without diabetes both in urban and rural areas. Among individuals without diabetes at baseline, age, living in rural areas, baseline BMI and weight change contributed to the development of diabetes independently. The multivariate adjusted relative risk (95% CIs) for incidence of diabetes were 1.