Poliomyelitic Virus in Sewage

Paul, John R.; Trask, James D.; Culotta, Charles S.

doi:10.1126/science.90.2333.258

Cited by 42 publications

(14 citation statements)

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“…The fact that the virus was able to withstand mailing overseas and mailing in summer heat is also of practical significance. It confirms previous experience of prolonged activity of virus in human stools and its stability in this medium (6) and is of importance in relation to the occurrence of the virus in sewage (23,24).…”

Section: Discussionsupporting

confidence: 89%

I. Poliomyelitic Virus in Human Stools

Trask

Paul

Vignec

1940

Journal of Experimental Medicine

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1. The detection of the virus of poliomyelitis in 10 stools from 8 individuals is reported. All were in relation to epidemic poliomyelitis and 7 of them represented well recognized forms of the disease. The positive stools were distributed among 56 specimens collected from 53 persons in the first 4 weeks of illness. 2. The ease of detection of virus was directly related to the non-paralytic type of disease and inversely related to the age of the patients. 3. The negative results with stools employed for controls gives point to the use of the fecal examinations as an epidemiological tool. 4. The stability of the virus in feces has been demonstrated by successful mailing of samples over long distances and during the heat of summer. 5. At least one infective dose per gram of fecal material was extracted from one stool.

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Section: Discussionsupporting

confidence: 89%

I. Poliomyelitic Virus in Human Stools

Trask

Paul

Vignec

1940

Journal of Experimental Medicine

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“…The technique was based on that used successfully in Charleston and Detroit (1)(2)(3). 4 liters of sewage were collected between 8 and 10 a.m., placed in the refrigerator to sediment for 3 to 6 hours when 700 cc.…”

mentioning

confidence: 99%

Periodic Examination of Sewage for the Virus of Poliomyelitis

Trask

Paul

1942

Journal of Experimental Medicine

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“…Y . In each of them we were fortunate in being allowed to examine the local sewage3 The first few tests in this series, which were made in Charleston, have already been described in a brief preliminary note (2). The present report deals with these earlier tests in more detail, as well as the later ones from the other two epidemics.…”

Section: (From the Departments Of Medicine And Pediatrics Yale Univementioning

confidence: 93%