Poly(dopamine) assisted deposition of adherent PPy film on Ti substrate

Popescu, Simona; Ungureanu, Camelia; Albu, Ana‐Maria; Pîrvu, Cristian

doi:10.1016/j.porgcoat.2014.06.023

Cited by 24 publications

(13 citation statements)

References 51 publications

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“…Ti/TiO 2 /T has a more hydrophilic character than Ti/TiO 2 /PDA-T; this can be explained by adding PDA in the system. The value of the contact angle obtained for titanium covered with PDA (42°) was similar with the value obtained in a previous study [28]. This means that the hydrophilic effect of torularhodin was attenuated through its embedding in PDA, as can be observed in the SEM images.…”

Section: Results and Discussion 31 Surface Characterizationsupporting

confidence: 89%

“…Alternatively, the presence of PDA on the surface of Ti/TiO 2 /PDA-T sample leads to a slight improve of corrosion stability, compared with Ti/TiO 2 /T, highlighting the role of the adherent PDA coating both in fixing torularhodin on the surface and in stability against corrosion, as was shown in a previous study [28]. All the samples have a lower corrosion rate compared with untreated Ti substrate, so all coatings contribute to improving the corrosion behaviour.…”

Section: Accepted Manuscriptsupporting

confidence: 67%

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Enhancing antimicrobial activity of TiO2/Ti by torularhodin bioinspired surface modification

Ungureanu

Dumitriu

Popescu

et al. 2016

Bioelectrochemistry

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Section: Results and Discussion 31 Surface Characterizationsupporting

confidence: 89%

Section: Accepted Manuscriptsupporting

confidence: 67%

Enhancing antimicrobial activity of TiO2/Ti by torularhodin bioinspired surface modification

Ungureanu

Dumitriu

Popescu

et al. 2016

Bioelectrochemistry

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“…In this study, PDA successfully enhanced the bonding force between the gelatin/rhBMP-2 layer and the surface of the porous 5%β-TCP/ Mg-3%Zn composite. The potential mechanism may involve the formation of a dopamine membrane with strong adhesion on the substrate surface [54][55][56] by self-polymerization under alkaline conditions.…”

Section: Discussionmentioning

confidence: 99%

Enhanced osteoinductivity and corrosion resistance of dopamine/gelatin/rhBMP-2–coated β-TCP/Mg-Zn orthopedic implants: An in vitro and in vivo study

et al. 2020

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Magnesium-based biomaterials are attracting increasingly more attention for orthopedic applications based on their appropriate mechanical properties, biodegradability, and favorable biocompatibility. However, the high corrosion rate of these materials remains to be addressed. In this study, porous β-Ca 3 (PO 4) 2 /Mg-Zn (β-TCP/Mg-Zn) composites were fabricated via a powder metallurgy method. The β-TCP/Mg-Zn composites with 6% porosity exhibited optimal mechanical properties, and thus, they were selected for surface modification. A novel dopamine/gelatin/recombinant human bone morphogenetic protein-2 (rhBMP-2) coating with demonstrated stability was prepared to further improve the corrosion resistance of the composite and enhance early osteoinductivity. The homogeneously coated β-TCP/Mg-Zn composite showed significantly improved corrosion resistance according to electrochemical and immersion tests. In addition, extracts from the dopamine/ gelatin/rhBMP-2-coated β-TCP/Mg-Zn composite not only facilitated cell proliferation but also significantly enhanced the osteogenic differentiation of Sprague-Dawley rat bone marrow-derived mesenchymal stem cells in vitro. Furthermore, in vivo experiments were performed to evaluate the biodegradation, histocompatibility, and osteoinductive potential of the coated composite. No obvious pathological changes in the vital visceral organs were observed after implantation, and radiography and hematoxylin-eosin staining showed strong promotion of new bone formation, matched composite degradation and bone regeneration rates, and complete absorption of the released hydrogen gas. Collectively, these results indicate that the dopamine/gelatin/rhBMP-2-coated β-TCP/Mg-Zn composite offers improved corrosion resistance, favorable biocompatibility, and enhanced osteoinductive potential for use in the fabrication of orthopedic implants.

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“…Extending the immersion times in dopamine solution, coverage of titanium surface by PDA was almost complete. AFM measurements demonstrated that the successive electrochemical deposition of polypyrrole on this surface led to the formation of PDA-PPy films with larger grains of PPy, resulting in a final increase of the coating roughness with respect to the PDA-PPy films obtained with shorter immersion times [73] (Figure 3). As highlighted by the above-reported examples, AFM is a fundamental analytical technique for electro-assisted polymers, since its 3D nature allows the calculation of changes in roughness and surface area variations due to differences in deposition parameters.…”

Section: Atomic Force Microscopymentioning

confidence: 99%

Surface Characterization of Electro-Assisted Titanium Implants: A Multi-Technique Approach

et al. 2020

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The understanding of chemical–physical, morphological, and mechanical properties of polymer coatings is a crucial preliminary step for further biological evaluation of the processes occurring on the coatings’ surface. Several studies have demonstrated how surface properties play a key role in the interactions between biomolecules (e.g., proteins, cells, extracellular matrix, and biological fluids) and titanium, such as chemical composition (investigated by means of XPS, TOF-SIMS, and ATR-FTIR), morphology (SEM–EDX), roughness (AFM), thickness (Ellipsometry), wettability (CA), solution–surface interactions (QCM-D), and mechanical features (hardness, elastic modulus, adhesion, and fatigue strength). In this review, we report an overview of the main analytical and mechanical methods commonly used to characterize polymer-based coatings deposited on titanium implants by electro-assisted techniques. A description of the relevance and shortcomings of each technique is described, in order to provide suitable information for the design and characterization of advanced coatings or for the optimization of the existing ones.

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Poly(dopamine) assisted deposition of adherent PPy film on Ti substrate

Cited by 24 publications

References 51 publications

Enhancing antimicrobial activity of TiO2/Ti by torularhodin bioinspired surface modification

Enhancing antimicrobial activity of TiO2/Ti by torularhodin bioinspired surface modification

Enhanced osteoinductivity and corrosion resistance of dopamine/gelatin/rhBMP-2–coated β-TCP/Mg-Zn orthopedic implants: An in vitro and in vivo study

Surface Characterization of Electro-Assisted Titanium Implants: A Multi-Technique Approach

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