Polycystic kidney disease in a Chartreux cat

Abstract

Polycystic kidney disease (PKD) is one of the most common genetic diseases in cats. It has been widely described in Persians and Persian-related cats and sporadically in other breeds. The purpose of the present paper is to describe the first reported case of PKD in a 12-year-old female Chartreux cat. The cat was referred with polyuria and polydipsia and enlarged and irregular kidneys at palpation. Multiple renal cysts and a single liver cyst were identified by ultrasound and the inherited pattern was confirmed by genetic test (polymerase chain reaction/restriction fragment length polymorphism (PCR/RFLP) assay). Chartreux cats should be included in the screening programme of PKD, and PKD should be always considered as a possible cause of chronic renal failure in this breed.

Urinary Tract

“…17,[38][39][40][41][42][43][44][45][46][47][48][49][50][51] Polycystic renal disease an autosomal dominant mutation, is the most common inherited renal disease of cats and prevalence in Persians is 37% to 49%. 17,[38][39][40][41][42][43][44][45][46][47][48][49][50][51] Polycystic renal disease an autosomal dominant mutation, is the most common inherited renal disease of cats and prevalence in Persians is 37% to 49%.…”

Feline abdominal ultrasonography: what’s normal? what’s abnormal? The kidneys and perinephric space

“…54 It is recognised in Persian and Persian-related cats most frequently, 23,[54][55][56][57][58] although it can occur more rarely in other breeds such as the Chartreux and British Shorthair. 22,59 Based on ultrasonographic examination, the prevalence of PKD in Persians varies from around 36% to 49%, 54,56,57,[60][61][62] although results from a later study suggest this figure may be decreasing as a result of screening programmes. 63 The condition is congenital and characterised by the presence of renal cysts.…”

Mechanisms, causes, investigation and management of vomiting disorders in cats: a literature review

“…Information that should be obtained is listed in Table 5. The distinction between vomiting and regurgitation is less clear in cats than in dogs, and cats with megaoesophagus, oesophagitis or hiatal hernia are often reported as vomiting [4b 135 , 4c 136 , 4d [137][138][139] 77,78 ], hyperthyroidism [4a 79,80 ] or diabetes mellitus [4a 147 ], while lower urinary tract disorders should be considered if there is dysuria, pollakiuria or stranguria [4d 134,148,149 ]. In such cases, there may also be associated physical examination findings, such as a distended painful bladder in cases of urethral obstruction [4d 134 ].…”

“…From the signalment, history and physical examination, the clinician should be able to categorise the patient as systemically 'well' (stable patient with no criteria for further assessment or treatment; Table 7) or 'unwell' Polydipsia may be seen with kidney disease [4d 77,78 ], hyperthyroidism [4a 79,80 ]…”