Polydopamine assisted immobilisation of copper(II) on titanium for antibacterial applications

Abstract

Copper(II) were immobilised onto medical titanium surface by polydopamine (PDA) chelating, to build intrinsic antibacterial implant materials for inhibition of implant infection. A scanning electrical microscope showed that the modified titanium surface morphology was a porous nanostructure. An energy dispersive spectrometer showed the existence of Cu, and X-ray photoelectron spectroscopy results further confirmed that the immobilised copper element was in the form of Cu(II). Bacteria plate colony counting results showed that modified titanium surface had decent antibacterial property, matching the ion release outcomes. It could be conclude that the PDA assisted Cu(II) immobilisation was an efficient and effective method for antibacterial modification of titanium.

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

“…Cu NPs were immobilized on stainless-steel substrates consisting of a poly(ethylene glycol diacrylate) (PEGDA) hydrogel by an electrochemical polymerization process that showed superior efficacy against E. coli and S. aureus ( 381 ) In a separate study, Cu(II) ions were incorporated in a polydopamine (PDA) coating on Ti substrates that resulted in a killing rate of 85% against S. aureus and E. coli. ( 382 )…”

Polyacrylamide-phytic acid-polydopamine conducting porous hydrogel for rapid detection and removal of copper (II) ions

“…The result indicates that the Cu 2+ has strong interaction with hydroxyl group and carboxyl groups of PAAM/PA/PDA hydrogel. In addition, an energy peak of Cu at 932.8 eV can be divided into four peaks, Cu 2p3/2 at 934.6 eV, Cu 2p1/2 at 954.9 eV, and the two shake-up peaks at 942.9 and 962.8 eV, indicating that Cu 2+ kept its valence state in the PAAM/PA/PDA hydrogel/Cu complexes (He et al, 2015).…”

Bioinspired and eco-friendly high efficacy cinnamaldehyde antibacterial surfaces

“…5 Polydopamine alone does not exhibit strong antibacterial activity, and so much research has been conducted into the post-functionalization of polydopamine coatings. Examples include the attachment of silver, [6][7][8] copper, 9,10 quaternary ammonium compounds, 11,12 zwitterionic compounds, 13 chlorhexidine, 14 antibiotics, 15 peptides, 16 or enzymes. 17 Many of these antibacterial polydopamine-based coatings are unsuitable for industrial scale-up due to their inherent multi-step syntheses, and often prohibitively long reaction times.…”