Polydopamine-modified ZIF-8 nanoparticles as a drug carrier for combined chemo-photothermal osteosarcoma therapy

Yin, Xueling; Ran, Siyi; Cheng, Haoyan; Zhang, Meng; Sun, Wei; Wan, Ying; Shao, Chunsheng; Zhu, Zhihong

doi:10.1016/j.colsurfb.2022.112507

Cited by 33 publications

(16 citation statements)

References 57 publications

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“…Zeolitic imidazolate framework-8 (ZIF-8) is an important MOF material constructed using zinc ions and imidazole ligands and has been widely used in catalysis and biomedical fields because of its easy preparation and excellent performance. 65,66 For example, ZIF-8 is stable under physiological conditions but will degrade in a mildly acidic microenvironment. This feature allows ZIF-8 to act as a pH-sensitive vehicle for drug delivery in antitumor and antibacterial applications.…”

Section: Synergistic Chemo-photothermal Antibacterial Therapymentioning

confidence: 99%

Synergistic photothermal antibacterial therapy enabled by multifunctional nanomaterials: progress and perspectives

Bai

Yang

Wen

et al. 2023

Mater. Chem. Front.

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Section: Synergistic Chemo-photothermal Antibacterial Therapymentioning

confidence: 99%

Synergistic photothermal antibacterial therapy enabled by multifunctional nanomaterials: progress and perspectives

Bai

Yang

Wen

et al. 2023

Mater. Chem. Front.

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“…Considering their use in PDT, Yin et al designed an amphiphilic zinc phthalocyanine polymer conjugate in the form of a monomolecular micelle. This nanocarrier showed efficient anti-psoriasis activity on psoriasis guinea pig models [ 63 ]. To further investigate these findings, zinc phthalocyanine was loaded into nanocapsules, including chitosan nanocapsules, poly-ε-caprolactone (PCL), and PCL-coated chitosan nanocapsules to test their photodynamic activity in psoriasis treatment.…”

Section: Nanotechnology Combined With Pdt In Psoriasis Treatment—futu...mentioning

confidence: 99%

“…The results showed enhanced penetration and retention of MTX and ALA passing through and into the skin of psoriatic mice [ 66 ]. A drug-targeting delivery system with MTX-loaded nanoparticle was also developed by Yin et al, who observed increased cancer cell apoptosis [ 63 ]. These results seem promising against psoriatic lesions, due to their potential ability to induce apoptosis in hyperproliferating keratinocytes.…”

Section: Nanotechnology Combined With Pdt In Psoriasis Treatment—futu...mentioning

confidence: 99%

An Update on Photodynamic Therapy of Psoriasis—Current Strategies and Nanotechnology as a Future Perspective

Makuch

Dróżdż

Makarec

et al. 2022

IJMS

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Psoriasis (PS) is an immune-mediated skin disease with substantial negative effects on patient quality of life. Despite significant progress in the development of novel treatment options over the past few decades, a high percentage of patients with psoriasis remain undertreated and require new medications with superior long-term efficacy and safety. One of the most promising treatment options against psoriatic lesions is a form of phototherapy known as photodynamic therapy (PDT), which involves either the systemic or local application of a cell-targeting photosensitizing compound, followed by selective illumination of the lesion with visible light. However, the effectiveness of clinically incorporated photosensitizers in psoriasis treatment is limited, and adverse effects such as pain or burning sensations are frequently reported. In this study, we performed a literature review and attempted to provide a pooled estimate of the efficacy and short-term safety of targeted PDT in the treatment of psoriasis. Despite some encouraging results, PDT remains clinically underutilized. This highlights the need for further studies that will aim to evaluate the efficacy of a wider spectrum of photosensitizers and the potential of nanotechnology in psoriasis treatment.

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“…Also, the molecular mechanisms related to the treatment of OS by PTT have also been studied, although they have not been fully elucidated. Studies have shown that the inhibitory effect of PTT on OS is related to apoptosis ( 81 – 83 ) and thermal ablation pathways ( 84 , 85 ). Flow cytometry is widely used in apoptosis analysis.…”

Section: Phototherapy Of Osteosarcomamentioning

confidence: 99%

Progress of phototherapy for osteosarcoma and application prospect of blue light photobiomodulation therapy

Yang

Jiang

et al. 2022

Front. Oncol.

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Osteosarcoma (OS) is the most common primary malignant bone tumor that mainly affects the pediatric and adolescent population; limb salvage treatment has become one of the most concerned and expected outcomes of OS patients recently. Phototherapy (PT), as a novel, non-invasive, and efficient antitumor therapeutic approach including photodynamic therapy (PDT), photothermal therapy (PTT), and photobiomodulation therapy (PBMT), has been widely applied in superficial skin tumor research and clinical treatment. OS is the typical deep tumor, and its phototherapy research faces great limitations and challenges. Surprisingly, pulse mode LED light can effectively improve tissue penetration and reduce skin damage caused by high light intensity and has great application potential in deep tumor research. In this review, we discussed the research progress and related molecular mechanisms of phototherapy in the treatment of OS, mainly summarized the status quo of blue light PBMT in the scientific research and clinical applications of tumor treatment, and outlooked the application prospect of pulsed blue LED light in the treatment of OS, so as to further improve clinical survival rate and prognosis of OS treatment and explore corresponding cellular mechanisms.

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Polydopamine-modified ZIF-8 nanoparticles as a drug carrier for combined chemo-photothermal osteosarcoma therapy

Cited by 33 publications

References 57 publications

Synergistic photothermal antibacterial therapy enabled by multifunctional nanomaterials: progress and perspectives

Synergistic photothermal antibacterial therapy enabled by multifunctional nanomaterials: progress and perspectives

An Update on Photodynamic Therapy of Psoriasis—Current Strategies and Nanotechnology as a Future Perspective

Progress of phototherapy for osteosarcoma and application prospect of blue light photobiomodulation therapy

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