2017
DOI: 10.4172/2472-0992.1000140
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Polyhydroxy Isocopalane from Indonesian’s Marine Sponge Callyspongia Sp. as Anti–White Spot Syndrome Virus from Litopenaeus vannamei

Abstract: The study of Indonesian's marine sponge Callyspongia Sp. against white spot syndrome virus has been conducted in June 2017. Bioactive metabolite terpene isolated based on methods of bioassay-guided separation. LCMS-ESI spectrum indicate that molecular formula C 24 H 44 O 5 with molecular weight is 412.576 m/z. FTIR spectrum indicated bioactive metabolite has ether C-O group at 1261 cm -1 and hydroxy group O-H at 3419 cm -1 . The spectrum of 1 H NMR and 13 C NMR indicated that metabolite active compound as poly… Show more

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Cited by 3 publications
(2 citation statements)
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“…The compound polyhydroxy isocopalane, a terpene, was extracted from marine sponge Callyspongia sp. in Indonesia [ 147 ]. The compound was found to exhibit strong antiviral activity against the WSSV at a concentration of 60 mg/L and resulted in 34% survival of the WSSV infected Litopenaeus vannamei .…”
Section: Applications In Aquaculturementioning
confidence: 99%
See 1 more Smart Citation
“…The compound polyhydroxy isocopalane, a terpene, was extracted from marine sponge Callyspongia sp. in Indonesia [ 147 ]. The compound was found to exhibit strong antiviral activity against the WSSV at a concentration of 60 mg/L and resulted in 34% survival of the WSSV infected Litopenaeus vannamei .…”
Section: Applications In Aquaculturementioning
confidence: 99%
“…The compound was found to exhibit strong antiviral activity against the WSSV at a concentration of 60 mg/L and resulted in 34% survival of the WSSV infected Litopenaeus vannamei . The presence of –OH group in the terpene was found to be responsible for inhibiting the replication of the virus in the host organism cell [ 147 ].…”
Section: Applications In Aquaculturementioning
confidence: 99%