2006
DOI: 10.1016/j.idairyj.2005.09.014
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Polymorphonuclear neutrophils and Escherichia coli proteases involved in proteolysis of casein during experimental E. coli mastitis

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Cited by 26 publications
(35 citation statements)
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“…Other indigenous enzymes may, however, also participate in casein degradation (Kelly et al, 2006) and many of these, e.g., the cathepsins, originate in leakage from milk leukocytes (Hurley et al, 2000). In addition, exogenous, heat stable proteases originating in psychrotrophs and pathogenic bacteria associated to the infected gland, will also contribute to the degradation of the caseins (Harayani et al, 2003;Haddadi et al, 2006).…”
Section: Resultsmentioning
confidence: 99%
“…Other indigenous enzymes may, however, also participate in casein degradation (Kelly et al, 2006) and many of these, e.g., the cathepsins, originate in leakage from milk leukocytes (Hurley et al, 2000). In addition, exogenous, heat stable proteases originating in psychrotrophs and pathogenic bacteria associated to the infected gland, will also contribute to the degradation of the caseins (Harayani et al, 2003;Haddadi et al, 2006).…”
Section: Resultsmentioning
confidence: 99%
“…Local recruitment of immune cells, such as macrophages and PMNs, is a crucial step in the development of an inflammatory response [29,30]. MPO (a surrogate marker for neutrophils [31]) activity in mammary tissue significantly increased as a result of infusion with LPS.…”
Section: Discussionmentioning
confidence: 99%
“…It also appears that the SCC is not a good criterion to diagnose mastitis in goats. The SCC level in goats milk is indeed prone to significant changes through the lactation period (Galina et al 1996;Haddadi et al 2006). In nonmastitic goats milk, the SCC can vary between 200,000 to 500,000 cells at the beginning of lactation, to 200,000 to 350,000 in the peak of lactation and to 1,000,000 to 3,100,000 or more at the end (Bergonier et al 1994).…”
Section: Introductionmentioning
confidence: 99%