2010
DOI: 10.1016/j.jcv.2010.08.015
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Polymyositis/dermatomyositis and nasopharyngeal carcinoma: The Epstein–Barr virus connection?

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Cited by 48 publications
(34 citation statements)
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“…In the present study, the DM group had higher serum EBV VCA-IgA titers compared with the control group. Our results confirmed previous reports [18] that showed a positive association between DM and EBV infection, especially in NPC patients from Southern China. This result highlights the role of EBV in the pathogenesis of NPC with DM, and the exact mechanism will require further investigation.…”
Section: Discussionsupporting
confidence: 93%
“…In the present study, the DM group had higher serum EBV VCA-IgA titers compared with the control group. Our results confirmed previous reports [18] that showed a positive association between DM and EBV infection, especially in NPC patients from Southern China. This result highlights the role of EBV in the pathogenesis of NPC with DM, and the exact mechanism will require further investigation.…”
Section: Discussionsupporting
confidence: 93%
“…EBV has been linked pathogenetically with both these conditions. [5] In our patient, immunostain for EBV-LMP1 was positive in the nasopharyngeal carcinoma specimen implicating EBV in the pathogenesis.…”
supporting
confidence: 47%
“…Malignancies have been identified prior to, following and in tandem with DM diagnosis and are most commonly identified one year following diagnosis. Cross-immune responses against myositis autoantigens or viral infections, including EBV, are thought to be responsible for the correlation between malignancy and DM (8,9). Common malignancies identified in individuals with DM include adenocarcinoma of the ovary, lung or gastrointestinal tract in western countries and nasopharyngeal non-keratinizing carcinoma in South Asia and China.…”
Section: Discussionmentioning
confidence: 99%