Polypoid adenocarcinoma of the cervix during pregnancy managed with conservative treatment

Abstract

I. Zapardiel).Fig. 1. Magnetic resonance imaging showing a 16-mm cervical lesion (white arrow) in a woman at 25 weeks of pregnancy. (R. Malhas). Fig. 1. A benign serous cystadenofibroma after intraoperative drainage and oophorectomy.

Cervical Cancer Associated with Pregnancy: Current Challenges and Future Strategies

“…From an oncological point of view, a systematic review totaling more than 600 cases confirmed an overall recurrence rate < 5% and a death rate < 3%, demonstrating the safety of this approach for small invasive cervical tumors [55]. RT in pregnancy has been investigated by many teams, as first-line therapy for patients diagnosed with tumors <2 cm (≤IB1 according to FIGO 2018) [33,[56][57][58][59][60][61][62][63][64][65][66] or, in rarer situations, for patients diagnosed with tumors >2 cm (≥IB2 according to FIGO 2018) [67][68][69][70][71][72][73][74][75]. RT can be performed either through abdominal [58][59][60]63,66,67,69,72,74,76] or vaginal approach (Dargent's method) [56,57,61,71,73,75,77,78], each technique being associated with its own advantages and drawbacks.…”

“…Cesarean-Radical Hysterectomy (CRH) vs. Delayed Radical Hysterectomy (RH) CRH was the preferred modality of surgical therapy across studies [56,59,68,. Its main indications were residual disease after radical trachelectomy, IB1 tumors in patients who do not wish to undergo fertility-preservation surgery, or for IB2-3 tumors after neoadjuvant chemotherapy (Figure 2).…”

“…Among the 27 patients undergoing vaginal delivery [68,86,94,99,107,113,115,140,150,[157][158][159][160][161][162][163][164][165], 9 patients experienced recurrence at the episiotomy site [86,115,157,158,[162][163][164][165]. In other situations, cervical cancer was revealed by metastasis at the episiotomy site several months after delivery, having remained occult during the pregnancy [157,162,164,[166][167][168][169][170].…”