Introduction: The presence of positive para-aortic lymph nodes in advanced cervical cancer remains the most important prognostic factor for survival and also defines the treatment. Our aim was to define the influence of staging para-aortic lymphadenectomy in patients’ survival. Material and Methods: The medical records of 74 patients with advanced cervical cancer (FIGO IIB-IVA) were reviewed. In 31 patients (41.9%), the assessment of lymph nodes was performed with imaging test (group 1) and in 43 (58.1%) within a surgical staging para-aortic lymphadenectomy (group 2). We compared both groups according to stage of disease, treatment, progression-free survival (PFS), and overall survival (OS). Results: The extended-field radiotherapy was performed in 44.2 and 19.4% of patients in surgical and imaging staging group, respectively (p = 0.045). The disease-free survival rate was 17.4 ± 17.4 months in group 1 and 14.4 ± 12.6 months in group 2 (p = 0.456). No differences in OS were found between these 2 groups (p = 0.676). Conclusions: Despite the higher diagnostic accuracy of surgical staging and the higher number of patient who received extended field radiotherapy, we did not find differences between the overall and PFS rates in both the studied groups. Further prospective study on a higher number of patients would be necessary.
I. Zapardiel).Fig. 1. Magnetic resonance imaging showing a 16-mm cervical lesion (white arrow) in a woman at 25 weeks of pregnancy. (R. Malhas). Fig. 1. A benign serous cystadenofibroma after intraoperative drainage and oophorectomy.
Since the 1990s, urban regeneration has emerged as the main initiative of the European Territorial Development Strategy. A series of integrated urban regeneration policies have subsequently been implemented to redress the socio-territorial imbalance in urban areas by improving the structure of opportunities available to inhabitants. The aim of the current paper is to evaluate the effect of such policies of proximity on the “essential retail trade” in neighborhoods in Andalusia. A quasi-experimental methodology was applied using the Difference in Differences (DiD) technique in order to ascertain the changes attributed to the intervention of the projects. In addition, change trends were analyzed using repeat measurements models for each calculated indicator and in the different considered contexts. The findings show an increase in the density and diversity of essential retail businesses in experimental and control areas. We found that in general, intervention had no significant effect on essential retail trade. However, the results do indicate that the impact of these plans is conditioned by the possible effect of different contexts and their specific dynamics (historical districts of large cities or towns on the one hand or peripheral suburbs on the other). The study may contribute to improving the design of integrated policies by controlling for the specificities of urban areas targeted by intervention.
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