Polypoidal Lesions in the Nasal Cavity

K, Kumari M K

doi:10.7860/jcdr/2013/4718.3025

Cited by 13 publications

(14 citation statements)

References 5 publications

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“…7 A similar figure of 9.2% of the non-neoplastic masses has been reported by Kumariet al 8 Eosinophilic angiocentric fibrosis (n=1, 6.4% of all non-neoplastic lesions) was the next frequent non-neoplastic lesion encountered ( Figure-2), represented by a single case having nasal obstruction with no response to local medication. On examination there was a firm mass in the left nasal cavity.…”

Section: 2supporting

confidence: 51%

Polypoid Nasal Masses; Surgical Pathology

Khan¹,

Asghar²,

Muhammad³

et al. 2017

TPMJ

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Section: 2supporting

confidence: 51%

Polypoid Nasal Masses; Surgical Pathology

Khan¹,

Asghar²,

Muhammad³

et al. 2017

TPMJ

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“…41.67% was the reported incidence in a similar study conducted by Modh SK et al 6 . Khan N et al 17 reported an incidence of 42.85% among benign lesions in this region.…”

Section: Discussionmentioning

confidence: 99%

Morphological Spectrum of Lesions in the Sinonasal Region

Raj¹,

Sharmila²,

Shrivastava³

et al. 2013

jemds

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INTRODUCTION:Nasal cavity and paranasal sinuses present a range of non-neoplastic and neoplastic lesions by virtue of their anatomic and histologic diversity. Although a presumptive diagnosis is arrived at based on presenting symptoms and imaging techniques, histopathology is the mainstay for definitive diagnosis and management of sinonasal lesions. AIMS AND OBJECTIVES: To study the incidence, mode of presentation and histologic types of sinonasal lesions in surgical pathology material. SETTING AND DESIGN: Retrospective retrieval of all sinonasal lesions and histopathologic analysis. MATERIALS AND METHODS: All sinonasal lesions, biopsied or excised over a period of three years between May 2010 and May 2013, were studied. The lesions were classified as non-neoplastic or neoplastic. Neoplasms were further categorised as benign and malignant. The histology was correlated with clinical features. Special stains and immunohistochemistry were done wherever indicated. RESULTS: In three years, sixty-one sinonasal lesions were reported, representing 0.47% of all surgical pathology specimens. Out of sixty-one cases, forty-one (67.21%) were non-neoplastic and twenty (32.79%) were neoplastic. Sinonasal lesions were common in the second and third decades of life, with male predominance. Among the non-neoplastic lesions, inflammatory polyps were the most common (80.49%). Among neoplasms, benign tumors (60%) were more frequent than malignant tumors (40%). Angiofibroma (6 cases-50%) was the commonest benign neoplasm and squamous cell carcinoma (4 cases-50%) was the commonest malignant neoplasm. CONCLUSION: Non-neoplastic and neoplastic lesions in the sinonasal region have similar clinical manifestations. Categorization based on histopathology is necessary for differential diagnosis, management and prognosis of these uncommon lesions. KEY WORDS: nasal cavity, paranasal sinuses, non-neoplastic, neoplastic, histopathology INTRODUCTION:The nasal cavity and paranasal sinuses form a functional unit of specialized tissues, each with its own aberrations. 1 They share many pathologic processes, most of which are inflammatory. 2 Exposure to various influences like chemical irritants, antigenic stimulants, and mechanical trauma results in deleterious consequences, including formation of tumors and tumorlike conditions. 3 Inflammatory polyps are a common cause of nasal obstruction, with a prevalence of 4% in the general population. 4 Benign tumors are relatively common, but malignant neoplasms are rare, accounting for 0.2-0.8% of all carcinomas and only 3% of those in the upper aero digestive tract. 5 Most of these lesions present as polypoid masses, making it difficult to distinguish nonneoplastic polyps from polypoid neoplasms clinically. 6 Histopathologic diagnosis is therefore mandatory for appropriate management and prognosis of sinonasal lesions. This study was undertaken to classify sinonasal lesions based on histopathology and to analyze their age and sex distribution.

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“…In study by Kalpana Kumari et al [25] malignant tumours were seen in 50% of the neoplastic cases and majority were sinonasal undifferentiated carcinomas (41%).…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological study of Sinonasal Masses

Mane

Agale

2017

APALM

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Background: Sinonasal mass is a common finding in the Otorhinolaryngology Department. These can be non-neoplastic or neoplastic. Nasal obstruction is the most common clinical presentation. Imaging studies are not always conclusive in these cases. So, the present study aimed at clinical presentation and histopathological classification of sinonasal masses.for histopathological examination and were stained by Hematoxylin and Eosin stain. Special stains were used wherever required. Immunohistochemistry was carried on cases with diagnostic difficulties. malignant tumours. Non-neoplastic lesions and benign tumours were commonly seen in middle age group while malignant tumours were seen in adult patients. Males were predominantly affected in non-neoplastic lesions and benign tumours. Malignant tumours showed female dominance. Nasal obstruction was the most common complaint. Overall, inflammatory nasal polyps were most common lesions. Inverted papillomas were most common benign tumours. Sinonasal undifferentiated carcinomas accounted for majority of malignant tumours. Conclusion:Sino-nasal masses or polyps can be non-neoplastic or neoplastic lesions and histopathological examination remains the mainstay in differentiating these lesions.

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Polypoidal Lesions in the Nasal Cavity

Cited by 13 publications

References 5 publications

Polypoid Nasal Masses; Surgical Pathology

Polypoid Nasal Masses; Surgical Pathology

Morphological Spectrum of Lesions in the Sinonasal Region

Clinicopathological study of Sinonasal Masses

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