2014
DOI: 10.1017/s1047951114002200
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Polytetrafluoroethylene pulmonary valve conduit implantation for chronic pulmonary insufficiency

Abstract: Pulmonary valve replacement in patients with congenital cardiac disease is now being performed with more liberal indications in light of the data that chronic pulmonary insufficiency is not a benign lesion. The beneficial effects of valve replacement with low operative mortality and morbidity support this approach. Many options exist for a pulmonary valve prosthesis, which underscores the fact that there is no ideal valve available. Our efforts are focussed around a synthetic valve that avoids the bio-degenera… Show more

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Cited by 11 publications
(13 citation statements)
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“…The treatment of these diseases usually requires the use of biomedical implants such as vascular bypass grafts, artificial heart valves, covered stent grafts, and heart patches. Polytetrafluoroethylene (PTFE) is one of the commonly used materials in making these prostheses . PTFE is a highly crystalline polymer with a hydrophobic, highly electronegative, and low friction surface, making it a suitable blood‐contacting biomaterial for applications such as vascular grafts .…”
Section: Introductionmentioning
confidence: 99%
“…The treatment of these diseases usually requires the use of biomedical implants such as vascular bypass grafts, artificial heart valves, covered stent grafts, and heart patches. Polytetrafluoroethylene (PTFE) is one of the commonly used materials in making these prostheses . PTFE is a highly crystalline polymer with a hydrophobic, highly electronegative, and low friction surface, making it a suitable blood‐contacting biomaterial for applications such as vascular grafts .…”
Section: Introductionmentioning
confidence: 99%
“…Polytetrafluoroethylene (PTFE) is commonly used for making various cardiovascular implants and medical devices such as vascular bypass grafts, balloon catheters, and heart patches . Also, PTFE is used for making some of the principal components of heart valves and stent grafts . Although PTFE has such widespread clinical applications, the implants that are made from this material are still associated with undesirable clinical events such as anastomotic neointimal hyperplasia and acute thrombosis .…”
Section: Introductionmentioning
confidence: 99%
“…[1][2][3] Also, PTFE is used for making some of the principal components of heart valves and stent grafts. 4,5 Although PTFE has such widespread clinical applications, the implants that are made from this material are still associated with undesirable clinical events such as anastomotic neointimal hyperplasia and acute thrombosis. 1,5,6 These events are primarily caused due to inappropriate interactions of endothelial cells (ECs), smooth muscle cells (SMCs), and platelets with PTFE.…”
Section: Introductionmentioning
confidence: 99%
“…In the earlier part of their experience, these investigators used PTFE material with 0.6 mm thickness and experienced a few cases of redo PVR because of immobile and calcified leaflets [13]. Currently, these investigators are using PTFE membrane with 0.1 mm thickness and anticipate improved valve durability [13,14]. Since June 2009, we have also been implanting this 0.1-mm PTFE bicuspid valve in the pulmonary position.…”
mentioning
confidence: 99%