Porcine reproductive and respiratory syndrome virus: Genetic diversity of recent British isolates

Genomic characterization and pathogenicity of a strain of type 1 porcine reproductive and respiratory syndrome virus

“…Within both type 1 and type 2, PRRSV shares extensively genetic variations with diversity of strains (Forsberg et al, 2002;Frossard et al, 2013;Meng, 2000;Murtaugh et al, 1998). Different strains of PRRSV have been shown to present the differential pathogenicity for pigs (Brockmeier et al, 2012;Li et al, 2010b;Zhou et al, 2009a).…”

Emergence of highly pathogenic porcine reproductive and respiratory syndrome (HP-PRRS) in medium-scale swine farms in southeastern Cambodia

“…The Nsp2 region was amplified and sequenced using the oligonucleotides listed in Table 2. Sequence assemblies were generated using SeqMan software version 7.1.0 (Lasergene, DNAS-TAR) (Frossard et al, 2013). Resulting sequences were aligned using the ClustalW algorithm with MEGA software (version 5.1) (Frossard et al, 2013 Feng et al, 2008).…”

“…Sequence assemblies were generated using SeqMan software version 7.1.0 (Lasergene, DNAS-TAR) (Frossard et al, 2013). Resulting sequences were aligned using the ClustalW algorithm with MEGA software (version 5.1) (Frossard et al, 2013 Feng et al, 2008). Samples were also screened for antibodies or antigens for a number of swine pathogens (Table 1), namely, classical swine fever (CSF), Aujeszky's disease, and Mycoplasma hyopneumoniae (M.…”

UK Pigs at the Time of Slaughter: Investigation into the Correlation of Infection with PRRSV and HEV

“…The economic and welfare impacts of the disease are considerable, as both the breeder and grower segments of the pig industry are affected [5]. All PRRSV infections in the UK characterized to date have been identified as being caused by genotype 1 virus, but the genetic diversity of the virus is continually increasing [6]. The phylogenetic analyses of UK PRRSV sequences have previously been based on data from samples submitted for diagnostic purposes, originating from clinical cases of PRRS, thereby possibly introducing a bias in our coverage of circulating strains.…”

“…Moreover, less pathogenic strains of genotype 1 PRRSV seem to cause a more persistent infection than highly pathogenic ones which are better resolved by the immune response [13]. Notably, viruses closely related to the modified-live vaccine used in the UK have previously been found circulating on farms with clinical PRRS [6]. …”