Possible risk for re-colonization with methicillin-resistant Staphylococcus aureus (MRSA) by faecal transmission

Klotz, Martina; Zimmermann, Stefan; Opper, Sandra; Heeg, Klaus; Mutters, Reinier

doi:10.1016/j.ijheh.2005.05.004

Cited by 28 publications

(18 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this study, the intestines were reported to be the only positive site out of five culture sites in 10% of the cases. Klotz and coworkers reported that in addition to a high frequency of 24% MRSA-positive stool cultures, 13% of the MRSA strains were first observed in the stool before detecting MRSA in other material from these patients [30]. Similarly, in a large Canadian surveillance study [40], comprising more than 10,000 adult patients, the perineal area was found to be the initial site of MRSA colonization or infection in 41% of the cases.…”

Section: Distribution Of Mrsa Detection Sitesmentioning

confidence: 96%

Intestinal carriage of Staphylococcus aureus: how does its frequency compare with that of nasal carriage and what is its clinical impact?

Acton¹,

Plat-Sinnige

Wamel

et al. 2008

Eur J Clin Microbiol Infect Dis

214

162

View full text Add to dashboard Cite

The bacterial species Staphylococcus aureus, including its methicillin-resistant variant (MRSA), finds its primary ecological niche in the human nose, but is also able to colonize the intestines and the perineal region. Intestinal carriage has not been widely investigated despite its potential clinical impact. This review summarizes literature on the topic and sketches the current state of affairs from a microbiological and infectious diseases' perspective. Major findings are that the average reported detection rate of intestinal carriage in healthy individuals and patients is 20% for S. aureus and 9% for MRSA, which is approximately half of that for nasal carriage. Nasal carriage seems to predispose to intestinal carriage, but sole intestinal carriage occurs relatively frequently and is observed in 1 out of 3 intestinal carriers, which provides a rationale to include intestinal screening for surveillance or in outbreak settings. Colonization of the intestinal tract with S. aureus at a young age occurs at a high frequency and may affect the host's immune system. The frequency of intestinal carriage is generally underestimated and may significantly contribute to bacterial dissemination and subsequent risk of infections. Whether intestinal rather than nasal S. aureus carriage is a primary predictor for infections is still ill-defined.

show abstract

Section: Distribution Of Mrsa Detection Sitesmentioning

confidence: 96%

Intestinal carriage of Staphylococcus aureus: how does its frequency compare with that of nasal carriage and what is its clinical impact?

Acton¹,

Plat-Sinnige

Wamel

et al. 2008

Eur J Clin Microbiol Infect Dis

214

162

View full text Add to dashboard Cite

show abstract

“…MRSA is released into the hospital environment either through aerosol, skin cells or stools of infected patient (Klotz et al, 2005 …”

Section: Mrsa Transmission In Hospital Settingsmentioning

confidence: 99%

Methicillin Resistant Staphylococcus aureus (MRSA): A Review

Grema¹,

Geidam²,

Gadzama³

et al. 2015

Adv. Anim. Vet. Sci.

View full text Add to dashboard Cite

“…The gastrointestinal tract has been identified as an important reservoir of MRSA in persistent carriers in adult patients [10][11][12][13][14], and in a pediatric intensive care unit [15]. Contrary to the data reviewed by Acton et al, rectal swabs were clearly inferior to stool samples in detecting persistent colonization [14].…”

Section: Discussionmentioning

confidence: 95%

Successful management of an MRSA outbreak in a neonatal intensive care unit

Heinrich¹,

Müeller²,

Bartmann³

et al. 2011

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

Abstract:We report an MRSA outbreak in our 25 bed tertiary neonatal intensive care unit (NICU), which was successfully contained. Patients and Methods: retrospective review of patient files, microbiology records and meeting protocols. Results: During the seven months of outbreak, 27 patients and 7 health care workers (HCWs) had positive cultures for MRSA. The outbreak was caused by the epidemic Rhine-Hessen strain, cultured isolates were monoclonal. After a sharp increase of the number of new MRSA-cases the installation of an outbreak management team (OMT) and implementation of comprehensive measures (extensive screening and decolonization strategy including orally applied vancomycin, isolation wards, intensive disinfection regimen) successfully terminated the outbreak within one month. Ten (53%) of 19 patients with completed follow up and all of the HCWs were decolonized successfully. Gastrointestinal colonization was present in 15 of 27 (56%) neonates, and was associated with poor decolonization success (30% vs. 78% in absence of gastrointestinal colonization); Conclusion: A comprehensive outbreak management can terminate an outbreak in a NICU setting within a short time. Thorough screening of nares, throat and especially stool is necessary for correct cohorting. Gastrointestinal decolonization in neonates seems difficult.

show abstract

Possible risk for re-colonization with methicillin-resistant Staphylococcus aureus (MRSA) by faecal transmission

Cited by 28 publications

References 8 publications

Intestinal carriage of Staphylococcus aureus: how does its frequency compare with that of nasal carriage and what is its clinical impact?

Intestinal carriage of Staphylococcus aureus: how does its frequency compare with that of nasal carriage and what is its clinical impact?

Methicillin Resistant Staphylococcus aureus (MRSA): A Review

Successful management of an MRSA outbreak in a neonatal intensive care unit

Contact Info

Product

Resources

About