Potassium and magnesium deficiency, its role in cardiovascular disease development and possibilities of correction

Барышникова, Г. А.; Chorbinskaya, S A; Степанова, И.И.; Blokhina, Olga E.

doi:10.26442/20751753.2019.1.190240

Cited by 6 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to the literature data, magnesium is one of the most important microelements in the body and provides ionic membrane processes in both nerve and muscle cells, and orotic acid causes a powerful impact on protein metabolism, and through it on other types of metabolismcarbohydrate, lipid and water-salt [12]. Acting as a natural calcium antagonist, magnesium takes part in muscle fiber relaxation, reduces platelet aggregation, and maintains a normal transmembrane potential in electrically excitable tissues [1]. In addition, magnesium provides suppression of nerve centers that stimulate sympathetic innervation and the renin-angiotensin system, and also enhances sodium excretion due to increased renal blood flow, ensuring the removal of excess sodium from the body as one of the important factors in increasing vascular tone.…”

Section: Results and Its Discussionmentioning

confidence: 99%

Influence of Metabolic Therapy on Life Quality in Patients With Atrial Fibrillation Paroxysms

Fushtey

Podsevahina

Palamarchuk

et al. 2022

Modern Medical Technology

View full text Add to dashboard Cite

Abstract. The goal of the study was to investigate the effect of magnesium orotate as a part of complex therapy in sinus rhythm restoring in patients with AF paroxysm, as well as to evaluate its effectiveness and effect on LQo with long-term use. Materials and research methods. We examined 56 patients (16 women and 40 men) with an average age of (61,5 ± 4,3) years with paroxysmal atrial fibrillation. All patients were divided into two groups. Patients of the 1st group (n=28) underwent medical cardioversion with amiodarone and magnesium orotate. Patients of the 2nd group (n=28) received only amiodarone. The time of sinus rhythm restoration, parameters of electrical instability of the atrial and ventricular myocardium after sinus rhythm restoration, patients life quality 3 months after discharge - were assessed in both groups. Results. The study allowed to reveal that the addition of magnesium orotate to the basic therapy of patients with atrial fibrillation increases the effectiveness of medical cardioversion and reduces the time of its onset. When using amiodarone and magnesium orotate, signs of electrical instability of the atrial myocardium (the number of paired and supraventricular extrasystoles) are significantly less according to the results of Holter electrocardiogram monitoring compared with amiodarone monotherapy. Atrial fibrillation caused a life quality parameters deviations in the form of an increase in the severity of the disease symptoms, physical activity limitation and psycho-emotional sphere disorders. 3 months after the treatment, it was noted that life quality in patients of the 1st group (complex therapy using magnesium orotate) was higher compared to patients of the 2nd group due to the improvement in the indicators of the "psycho-emotional" component. Conclusions. The addition of magnesium orotate to the basic therapy of paroxysmal atrial fibrillation can significantly improve the clinical course of the disease in patients and their life quality after 3 months treatment period.

show abstract

Section: Results and Its Discussionmentioning

confidence: 99%

Influence of Metabolic Therapy on Life Quality in Patients With Atrial Fibrillation Paroxysms

Fushtey

Podsevahina

Palamarchuk

et al. 2022

Modern Medical Technology

View full text Add to dashboard Cite

show abstract

“…In addition, magnesium reduces sympathetic effects on the heart, thereby eliminating the damaging effect of catecholamines on the myocardium (Gröber et al 2015;Trisvetova 2018). As a result, magnesium aspartate has an adaptogenic effect, increasing the body's resistance and endurance to various stressful influences (Baryshnikova et al 2019).…”

Section: Resultsmentioning

confidence: 99%

Possible prospects for using modern magnesium preparations for increasing stress resistance during COVID-19 pandemic

Sankova

Kytko

Meylanova

et al. 2020

RRP

View full text Add to dashboard Cite

Introduction: The relevance of the issue of increasing stress resistance is due to a significant deterioration in the mental health of the population caused by the special conditions of the disease control and prevention during the COVID-19 pandemic. Recently, the decisive role in the severity of clinico-physiological manifestations of maladjustment to stress is assigned to magnesium ions. The aim of the work was to study the magnesium importance in the body coping mechanisms under stress for the pathogenetic substantiation of the magnesium correction in an unfavorable situation of disease control and prevention during the COVID-19 pandemic. Materials and methods: The theoretical basis of this scientific and analytical review was an analysis of modern Russian and foreign literature data posted on the electronic portals MEDLINE, PubMed-NCBI, Scientific Electronic Library eLIBRARY.RU, Google Academy, and CyberLeninka. Results and discussion: It was shown that the total magnesium level in the body plays the indicator role of the body functional reserves. Acute and chronic stresses significantly increase the magnesium consumption and cause a decrease in its body content. Magnesium deficiency is one of the main pathogenetic mechanisms of reducing stress resistance and adaptive body reserves. Arising during the COVID-19 pandemic, increased nervous and emotional tension, the lack of emotional comfort and balance can lead to the onset or deterioration of magnesium deficiency, which manifests itself in mental burnout and depletion of adaptive capacities. The inability to synthesize magnesium in the body necessitates including foodstuffs high in magnesium in the population diet during this period. The appointment of magnesium preparations is pathogenetically justified with moderate and severe magnesium deficiency. This therapy should take into account the major concomitant diseases, severity of magnesium deficiency, and a patient’s age. Conclusion: magnesium correction, carried out during the COVID-19 pandemic, will contribute to increasing stress resistance, preventing mental diseases and improving the population’s life quality.

show abstract

To the health of the nation through multi-level educational programs for the population in the field of optimal nutrition

Погожева

2021

Medicinskij sovet

View full text Add to dashboard Cite

Introduction. Healthy nutrition is the most important component of the quality of life, which is understood as an integral indicator of the mental, physical and social functioning of a person. However, the diet of Russians is not enough vegetables and fruits, dairy products, excess sugar, salt, products containing animal fat and trans fats. Violations of the structure of nutrition, nutritional status lead to the development of alimentary-dependent diseases, primarily cardiovascular, and in particular, arterial hypertension.Goal. Study of alimentary risk factors for arterial hypertension.Materials and methods. The data of the survey of VTSIOM and the company Gideon Richter “Food habits of Russians”, September 2020”, conducted by telephone survey in at least 80 regions (1,600 respondents over 18 years old), are analyzed.Results and discussion. The diet of the adult population of Russia is characterized by a high consumption of animal fat (frequent consumption of fatty dairy products-52% of respondents, butter-61%, sausage products-48%), salt (pickles and marinades – 42%), added sugar (confectionery – 47%) with a lack of fruit, fish and seafood. 23% of respondents add salt to ready meals, and 43% use frying when cooking. Arterial hypertension was noted in 52% of respondents, who, compared to normotonics, less often (32-39%) include in their diet foods that are sources of potassium and magnesium (apricots, bananas, dried fruits, nuts, seeds, etc.), and more often-pickles, marinades (47%) and mayonnaise (45%), containing a large amount of salt, as well as add salt to ready meals (24%).Conclusions. In order to prevent arterial hypertension in Russians, it is necessary to increase their intake of potassium and magnesium, limit the content of table salt in the diet, which will be facilitated by the widespread introduction of educational programs on healthy nutrition.

show abstract

Potassium and magnesium deficiency, its role in cardiovascular disease development and possibilities of correction

Cited by 6 publications

References 0 publications

Influence of Metabolic Therapy on Life Quality in Patients With Atrial Fibrillation Paroxysms

Influence of Metabolic Therapy on Life Quality in Patients With Atrial Fibrillation Paroxysms

Possible prospects for using modern magnesium preparations for increasing stress resistance during COVID-19 pandemic

To the health of the nation through multi-level educational programs for the population in the field of optimal nutrition

Contact Info

Product

Resources

About