“…Patients in CCF with oedema have been shown to have high concentrations of exchangeable sodium even when this is expressed as mmoljkg body weight (Farber & Soberman, 1956;Birkenfeld, Leibman, O'Meara & Edelman, 1958). In patients free of oedema, results have varied : Carroll, Gotterer & Altshuler (1965) found an increase in exchangeable sodium, whereas Lockey, Longmore, Ross & Sturridge (1966) and Oleson (1966) found no significant increase. Flear, Quinton, Carpenter, Domenet & Sivyer (1966) and Lockey et al (1966) have reported a significant depletion of total exchangeable potassium in patients with cardiac failure.…”