Potenciais evocados auditivos de média e longa latências em adultos com AIDS

Abstract

Background: middle and late latency auditory evoked potentials. Aim: to verify the occurrence of middle and late latency auditory evoked potentials disorders in adults with Acquired Immunodeficiency Syndrome (AIDS). Method: middle and late latency auditory evoked potentials of 8 individuals with AIDS, with ages ranging from 10 to 51 years, with normal hearing, or with sensoryneural hearing losses up to moderate, and normal results in the Auditory Brainstem Response, comparing the results with the responses obtained for a control group which was composed by 25 individuals, with ages ranging from 19 to 24 years, with no hearing complaints and with normal hearing and normal results in the Auditory Brainstem Response. Results: the Pa wave latency and amplitude averages in the C3/A2 and C4/A1 modalities, and the average of the P300 wave were analyzed. No significant differences were observed in the Pa wave amplitude and latency averages between the groups, although a non-statistically significant increase was observed in the latency and a decrease in the amplitude of such wave for the research group in the C3/A2 modality. The latency of the P300 wave was significantly longer to the left for the research group. It was also observed a longer latency to the right, although this was not statistically significant. Conclusion: adult individuals with AIDS do not present alterations in the middle latency auditory evoked potential and do present alterations in the cognitive potential, indicating a disorder in the cortical regions of the auditory pathway and a deficit in the cognitive processing of auditory information for this population. Such findings stress the importance of a careful investigation of the auditory function of individuals with AIDS, thus favoring the therapeutic planning.

Potenciais evocados auditivos de longa latência em adultos com HIV/Aids

“…The results of the present study agree with the findings of Matas et al (23), which evaluated 8 HIV/ AIDS by means of the Auditory Middle Latency Evoked Potential and the P300 and compared the results to the ones of the control group. The authors verified the increase of the latency of P300 wave in the research group, suggesting the impairment of the auditory path in cortical regions and a deficit on the cognitive processing of the auditory information, stressing the importance of the careful assessment of the auditory function in individuals with AIDS.…”

“…It can be verified that there was statistically significant difference between groups with the control group with smaller latencies, which agrees to previous studies (11,(19)(20)(21)(22)(23) that also found disorders in the P300 latencies of individuals with HIV/AIDS.…”

Saúde auditiva, o vírus da imunodeficiência humana e a síndrome da imunodeficiência adquirida: uma revisão

“…Um segundo subtema abordado envolve a AIDS ou o HIV como fatores de risco para patologias auditivas. Nos Estados Unidos, o National Institutes of Health estima que 75% dos adultos portadores da AIDS têm algum tipo de distúrbio auditivo, causado pela própria doença, por infecções oportunistas ou por tratamentos com medicações ototóxicas [17][18][19][20][21][22] .…”

Editorial

“…A MEDLINE journal should have authors of several countries in order to better divulge the state of the art and the speech-language and hearing science. Verificar a ocorrência de alterações nos potenciais evocados auditivos de média e longa latências em indivíduos adultos portadores da síndrome da imunodeficiência adiquirida (AIDS) foi o objetivo do estudo de Matas et al (2006). Os resultados encontrados indicam não significância para média latência e significância para longa latência.…”

“…The study of Matas et al (2006) aimed to verify the occurrence of middle and late latency auditory evoked potentials disorders in adults with Acquired Immunodeficiency Syndrome (AIDS). The obtained results were not significant for middle latency and significant for late latency.…”