“…A loss of valve functionality leads to poor speech and requires replacement of the device (Ticac et al, 2010;Leonhard and Schneider-Stickler, 2015). Moreover, the microbial colonization may act as a reservoir of potential pathogens which, subsequent to aspiration, may lead to life-threatening infections such as pneumonia (Delank and Scheuermann, 2008). The mean VP lifespan is highly variable across different studies and has historically been reported as being between 120 and 200 days (Schafer et al, 2001;Sayed et al, 2012).…”