Predictors of peritoneal carcinomatosis in patients with gastric cancer treated at a single institution in Brazil

Fanelli, Marcello Ferretti; Paiva, Tadeu Ferreira; Silva, Milton J B; Benevides, Carlos Frederico Lopes; Guimarães, Andréa Paiva Gadêlha; Gimenes, Daniel Luiz; Pinheiro, Edilson D.; Rinck, José Augusto; Sanches, Solange Moraes; Mello, Celso Abdon Lopes de; Dettino, Aldo Lourenço Abbade; Cruz, Marcelo Rocha; Melo, Leônidas Carrijo Azevedo; Formiga, Maria Nirvana; Lima, Vladmir Cláudio Cordeiro de; Chinen, Ludmilla T.D.

doi:10.1002/jso.21349

Cited by 11 publications

(11 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Most patients were at tumor at stage III (29.5%) and 31 at stage IV (50.8%). Most of the patients were also in stage IV in many other studies also [16,22,23]. Among differentiation moderately differentiated 45.9% & poorly differentiated was 39.3%.In a study of our country.…”

Section: Discussionmentioning

confidence: 54%

“…Strikingly most of the patients in the study group was in advanced stage and a significant proportion was not suitable for operation. Most of the patients were also in stage IV in many other studies also [16,22,23].…”

Section: Discussionmentioning

confidence: 78%

“…Among the non resectable cases gastric bypass surgery in 14.8% patients. Fanelli F et al [23] Forty percent of the patients underwent gastrectomy. Ucar E et al [16], Total gastrectomy was performed in 58 patients, subtotal gastrectomy in 25, and gastric bypass surgery in 12.…”

Section: Discussionmentioning

confidence: 99%

“…The presence of peritoneal involvement was diagnosed though one of the following means: ultrasonography or computed tomography, a positive cytology after peritoneal aspiration or lavage, ascetic fluid aspiration or direct visualization through open surgery. Fanelli F et al [23] also include same criteria for peritoneal metastasis.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Clinical Significance of CA125 Level with Clinicopathological Variables and Peritoneal Dissemination in Patients with Gastric Carcinoma

Shirin¹,

Rahman²

2016

GHOA

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical Significance of CA125 Level with Clinicopathological Variables and Peritoneal Dissemination in Patients with Gastric Carcinoma

Shirin¹,

Rahman²

2016

GHOA

View full text Add to dashboard Cite

“…Most of the patients were also in stage IV in many other studies also. 12,17,19 Among differentiation well differentiated 9(14.8%), moderately differentiated 28 (45.9%) & poorly differentiated was 24 (39.3%). In a study of our country, 357 (57.12%) of the gastric adenocarcinomas were found poorly differentiated, 80 (12.8%) were well differentiated and 84 (13.44%) were moderately differentiated.…”

Section: Discussionmentioning

confidence: 98%

Relationship of clinicopathological parameters and preoperative CA19-9 level in patients with gastric cancer

et al. 2015

View full text Add to dashboard Cite

Prognostic factors analysis of 138 patients with stage IV gastric cancer

Zhuang

Shen

2010

Chin. -Ger. J. Clin. Oncol.

View full text Add to dashboard Cite

Gastric cancer is one of the most common tumor in our country. The overall survival of 5-year in patients with metastatic gastric cancer was only 3.1% [1] . Many factors were associated with the prognosis in patient with the IV stage gastric cancer. The present retrospective study evaluated baseline patient-or tumor-related prognostic factors in 138 patients with the IV stage gastric cancer, and the outcome could help clinicians and patients in clinical decision-making and treatment tailoring based on the estimated prognosis. Material and methods Patient selectionFrom 1st January 2003 to 31st December, all of the stage IV patients with diagnosed metastatic were slected at the Second Affiliated Hospital of Soochow University. All of them were treated with one or more cycles of platinum-based chemotherapy. Data collectionWe designed a table in Microsoft Excel to collect the patients' clinical data. The data we gathered included: population data, clinical manifestations, pathological type and Borrmann type, chemotherapy regimens, complete blood cell count and serum biochemistry, computed tomography (CT) scan. Different variables were dichotomized with different cutoff points and assigned a value. The cutoff point of the serum total bilirubin level and serum alkaline phosphatase level were chosen as the upper normal value, while the serum albumin level were chosen as the lower normal value. The number of metastatic sites were determined by the imagic examination or surgical operation and the metastatic sites in the same organ were considered as Table 1. Follow-up138 patients were enrolled in this study. And we follow-up by telephone, and the last data were 12th March, 2008. Ten of them were lost and were regarded as dead. The rate of follow-up was 93.24%.Abstract Objective: We evaluated the prognostic factors of patients with stage IV gastric cancer. Methods: In the current retrospective study, 138 patients of stage I gastric cancer treated with platinum-based chemotherapy were analyzed. Survival rate was estimated by using Kaplan-Meier method. The prognostic factors were analyzed using univariate (Log rank) and multivariate (Cox model) analysis methods. Results: Univariate analysis showed and multivariate analysis showed that poor performance status (P = 0.001), weight loss (P = 0.001), depth of invasion (P = 0.000), presence of peritoneal metastasis (P = 0.005), more than 1 metastatic site (P = 0.029) and elevated total bilirubin (P = 0.018) were confirmed as independent prognostic factors. According to the outcomes of the Cox model analysis, a formula of the prognostic index was developed. According to the values of PI, 16 patients were categorized as the good risk group, 28 patients were categorized as the moderate risk group and 8 patients were categorized as the poor risk group, respectively. The survival ratios of 6 months, 12 months and 24 months of the good risk group were 75.00%, 50.00%, 25.00%, respectively. The survival ratios of 6 month, 1-year and 2-year of the moderate risk group were 71.79%, 28.57%, 7...

show abstract

Predictors of peritoneal carcinomatosis in patients with gastric cancer treated at a single institution in Brazil

Abstract: Patients with gastric cancer presenting with signet-ring histology, vascular invasion, or visceral metastasis appear to be at higher risk for the development of peritoneal carcinomatosis.

Cited by 11 publications

References 30 publications

Clinical Significance of CA125 Level with Clinicopathological Variables and Peritoneal Dissemination in Patients with Gastric Carcinoma

Clinical Significance of CA125 Level with Clinicopathological Variables and Peritoneal Dissemination in Patients with Gastric Carcinoma

Relationship of clinicopathological parameters and preoperative CA19-9 level in patients with gastric cancer

Prognostic factors analysis of 138 patients with stage IV gastric cancer

Contact Info

Product

Resources

About