Prehydration is Effective for Rapid Control of Recalcitrant Atopic Dermatitis

Hajar, Tamar; Hanifin, Jon M.; Tofte, Susan J.; Simpson, Eric L.

doi:10.1097/der.0000000000000019

Cited by 15 publications

(7 citation statements)

References 12 publications

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“…9,13,26 Our results support the recommendation of routine moisturizer application immediately following bathing before SC hydration is decreased to the pre-bathing level. 12,22 Regarding the style of bathing, there are inconsistencies. Each person's method of bathing is a routine, culturally, ritually, and esthetically based practice.…”

Section: Discussionmentioning

confidence: 99%

Skin hydration and transepidermal water loss after bathing compared between immersion and showering

Nitiyarom

Anuntarumporn

Wisuthsarewong

2021

Skin Research and Technology

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The skin is the largest organ of the human body. It provides several defensive and regulatory functions between the external environment and the internal tissues, including prevention of infection, maintenance of water content level, and reduced penetration of allergens and irritants. 1 The most important function of the skin is providing an effective physical barrier, which consists almost entirely of the epidermis, particularly its superficial layer -the stratum corneum (SC). 1 The SC serves as the principal barrier against the percutaneous penetration of chemicals and microbes. It is involved in the regulation of water release from the SC into the atmosphere, which is known as transepidermal water loss (TEWL). 1 The biophysical parameters of the skin, such as hydration, TEWL, skin surface pH, and elasticity, are all reflections of skin function. 2 Epidermal hydration or SC water content is assessed by measuring the electrical capacitance of the skin with a Corneometer ™ . 3 TEWL is considered to be one of the most relevant markers for measuring skin barrier function. [4][5][6][7]

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Section: Discussionmentioning

confidence: 99%

Skin hydration and transepidermal water loss after bathing compared between immersion and showering

Nitiyarom

Anuntarumporn

Wisuthsarewong

2021

Skin Research and Technology

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“…These results are unexpected given the previous literature published on SS. [3][4][5] Three studies have reported great benefit using SS: a retrospective study of adults with severe, refractory dermatitis; a prospective study of combat soldiers with severe AD flares; and a retrospective review of children and adults with severe or moderate AD. In both retrospective studies, the methods of assessing AD improvement are not well validated.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 Previous studies have shown that SS results in marked improvement or disease clearance in nearly all patients. [3][4][5] There is limited evidence of its benefit in the pediatric population; use of SS in children is based primarily on uncontrolled case series and expert opinion. This study was undertaken to evaluate whether TCS application using SS works better than TCS applied to dry skin for the treatment of childhood AD.…”

mentioning

confidence: 99%

A randomized, controlled trial comparing topical steroid application to wet versus dry skin in children with atopic dermatitis (AD)

Kohn

Kang

Antaya

2016

Journal of the American Academy of Dermatology

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“…5 min), followed by gentle drying with smooth cloths and application of emollients while the skin is still damp [ 8 ]. When inflamed lesions are poorly responsive to anti-inflammatory treatment, the so-called soak and smear method has been recommended because it can produce a higher absorption of topical steroids; this method consists of washing for 20 min followed by the application of topical anti-inflammatory steroid, without first drying the affected areas [ 9 , 10 ]. Although there are currently few clinical studies, the use of non-soap cleansers and synthetic detergents (the so-called syndets) are recommended; these products have a slightly acidic pH (preferably about 5.5–6), should be free or relatively free of preservatives and perfumes, and have liquid formulations to facilitate rinsing [ 4 , 11 , 12 ].…”

Section: Topical Therapiesmentioning

confidence: 99%

Consensus Conference on Clinical Management of pediatric Atopic Dermatitis

et al. 2016

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The Italian Consensus Conference on clinical management of atopic dermatitis in children reflects the best and most recent scientific evidence, with the aim to provide specialists with a useful tool for managing this common, but complex clinical condition. Thanks to the contribution of experts in the field and members of the Italian Society of Pediatric Allergology and Immunology (SIAIP) and the Italian Society of Pediatric Dermatology (SIDerP), this Consensus statement integrates the basic principles of the most recent guidelines for the management of atopic dermatitis to facilitate a practical approach to the disease. The therapeutical approach should be adapted to the clinical severity and requires a tailored strategy to ensure good compliance by children and their parents. In this Consensus, levels and models of intervention are also enriched by the Italian experience to facilitate a practical approach to the disease.

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Prehydration is Effective for Rapid Control of Recalcitrant Atopic Dermatitis

Cited by 15 publications

References 12 publications

Skin hydration and transepidermal water loss after bathing compared between immersion and showering

Skin hydration and transepidermal water loss after bathing compared between immersion and showering

A randomized, controlled trial comparing topical steroid application to wet versus dry skin in children with atopic dermatitis (AD)

Consensus Conference on Clinical Management of pediatric Atopic Dermatitis

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