Preliminary Correlations for Characterizing the Morphology of Abdominal Aortic Aneurysms as Predictor of Rupture

Alonso, Guillermo Vilalta; Soudah, Eduardo; Alonso, José Alberto Vilalta; Lipsa, Laurentiu Mihai; Nieto, Félix; Pérez, M.Á.; Vaquero, Carlos

doi:10.1007/978-3-319-38869-4_1

Cited by 1 publication

(3 citation statements)

References 8 publications

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“…The asymmetry is defined as β=(D − La)/La, where D is the maximum diameter of the aneurysm and La is the anterior length measured in the plane of maximum diameter of the aneurysm. 15,17,19,23,82,86 Because the posterior wall is close to the spine, the normal anatomy of AAA is β<1. 26 The AAA is more symmetric and with a lower risk of rupture if β tends to 1.…”

Section: Asymmetrymentioning

confidence: 99%

“…15,17,80,81 Soudah et al 37 established 28 virtual AAA models for simulation, and the results showed a significant correlation between peak wall shear stress (PWSS) and maximum diameter, asymmetry, and deformation rate. But in another study, Alonso et al 82 assessed the correlations between the main hemodynamic parameters and different geometric indicators of AAA. The simulation results showed that there is no significant correlation between deformation rate and PWSS or peak intraluminal pressure (PIP).…”

Section: Deformation Ratementioning

confidence: 99%

“…To explore the correlation between morphological characteristics of AAA and the rupture risk, Alonso et al 82 reconstructed 6 models characterized by geometric parameters to calculate the stress distribution, in which AAA volume is significantly correlated with both PWSS and PIP. However, 13 AAA patient-specific models were calculated, and Guillermo et al found no significant correlation between AAA volume and PWSS or PIP.…”

Section: Aaa Volumementioning

confidence: 99%

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Narrative Review of Risk Assessment of Abdominal Aortic Aneurysm Rupture Based on Biomechanics-Related Morphology

Ren

Guidoin

et al. 2022

J Endovasc Ther

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An abdominal aortic aneurysm (AAA) is a typical aortic disease with serious complications. In clinical practice, the decision to intervene in treatment depends on the rupture risk of AAA. Therefore, monitoring the progression of the disease and accurately assessing the rupture risk is of great importance for its treatment. Studies have shown that the biomechanical indicators based on multi-scale models are more effective in accurately assessing the rupture risk of AAA. However, using computational fluid dynamics (CFD) to simulate the biomechanical environment is a cumbersome and time-consuming process, which is inadequate to meet the needs of clinical monitoring and quick decisions. While the hemodynamic environment of AAA is heavily dependent on geometry, more and more biomechanics-related morphological parameters have been raised and validated. In this review, we summarized typical morphological parameters associated with AAA rupture and their relationships with the mechanical environment, including maximum diameter, deformation rate, saccular index, asymmetry, AAA volume, tortuosity, and intraluminal thrombus (ILT), providing a reference for clinical preoperative risk assessment. Clinical Impact Studies have shown that the biomechanical indicators based on multi-scale models are more effective in accurately assessing the rupture risk of AAA. To meet the need for clinical monitoring and rapid decision making, the typical morphological parameters associated with AAA rupture and their relationships with the mechanical environment have been summarized, which provide a reference for clinical preoperative risk assessment of AAA.

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