Preliminary Report of the Safety and Efficacy of Hyperbaric Oxygen Therapy for Specific Complications of Lung Transplantation

Higuchi, Terumi; Oto, Takahiro; Millar, Ian; Levvey, B.; Williams, Trevor; Snell, Gregory I

doi:10.1016/j.healun.2006.08.006

Cited by 19 publications

(14 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, there are only few case reports and non-randomized studies about the use of HBO2 therapy in this patient population. Recently, Higuchi et al presented 4 patients with sternal osteomyelitis after lung transplantation who received surgical debridement, antimicrobial treatment and adjunctive HBO2 therapy [10]. Three of them improved significantly and the authors concluded that HBO2 therapy was safe and effective for the management of infection complication.…”

Section: Discussionmentioning

confidence: 99%

“…Higuchi et al reported the initiation of HBO2 therapy for patients with persistent osteomyelitis after standard treatment [10]. Barili et al started early HBO2 therapy after the diagnosis of sternal surgical site infection [20].…”

Section: Discussionmentioning

confidence: 99%

“…There are only few reports about the additional HBO2 therapy for patients who develop sternal osteomyelitis after sternotomy. Most of the results are effective and successful [10,11]. The aim of this retrospective study was to evaluate the efficacy of HBO2 therapy in patients with sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery

Chen

Shie

et al. 2011

J Cardiothorac Surg

View full text Add to dashboard Cite

PurposeA retrospective study to evaluate the effect of hyperbaric oxygen (HBO2) therapy on sternal infection and osteomyelitis following median sternotomy.Materials and methodsA retrospective analysis of patients who received sternotomy and cardiothoracic surgery which developed sternal infection and osteomyelitis between 2002 and 2009. Twelve patients who received debridement and antibiotic treatment were selected, and six of them received additional HBO2 therapy. Demographic, clinical characteristics and outcome were compared between patients with and without HBO2 therapy.ResultsHBO2 therapy did not cause any treatment-related complication in patients receiving this additional treatment. Comparisons of the data between two study groups revealed that the length of stay in ICU (8.7 ± 2.7 days vs. 48.8 ± 10.5 days, p < 0.05), duration of invasive (4 ± 1.5 days vs. 34.8 ± 8.3 days, p < 0.05) and non-invasive (4 ± 1.9 days vs. 22.3 ± 6.2 days, p < 0.05) positive pressure ventilation were all significantly lower in patients with additional HBO2 therapy, as compared to patients without HBO2 therapy. Hospital mortality was also significantly lower in patients who received HBO2 therapy (0 case vs. 3 cases, p < 0.05), as compared to patients without the HBO2 therapy.ConclusionsIn addition to primary treatment with debridement and antibiotic use, HBO2 therapy may be used as an adjunctive and safe treatment to improve clinical outcomes in patients with sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery

Chen

Shie

et al. 2011

J Cardiothorac Surg

View full text Add to dashboard Cite

show abstract

“…После трансплантации сердца при использовании ГБО проиходит стимулирование образования коллагенового матрикса [71]. Доказано положительное влияние ГБО у пациентов после трансплантации легких, в частности при инфекционных осложнениях, когда другие методы оказались неэффективными или непригодными [72,73].…”

Section: гипербарическая оксигенация в посттрансплантационном периодеunclassified

Hyperbaric oxygenation in transplantology

Левина¹,

Евсеев²,

Хубутия³

et al. 2020

Transplantologiâ (Mosk.)

View full text Add to dashboard Cite

The ability to eliminate any form of oxygen debt by transporting oxygen to organs and tissues, by dissolving it in body fluids, brings hyperbaric oxygenation to a new level of application in transplantology. The review discusses the pathophysiological aspects of hyperbaric oxygenation during ischemia and reinfusion, especially when used in transplantology, and also investigations on the use of hyperbaric oxygenation in model experiments and in clinical practice. Analysis of the efficacy of hyperbaric oxygenation therapy at various stages of the transplantation process (preconditioning, donation, organ storage, in the early and late post-transplant periods) allows us to conclude that this method should be more widely involved in transplantation practice.Authors declare no conflict of interest.

show abstract

“…Кроме того, показано, что применение ГБО снижает степень ишемического поражения трансплантированного органа [2], снижает отек [21], улучшает капиллярную пролиферацию и площадь сосудов и стимулирует образование коллагенового матрикса [5,22]. Эффект ГБО выражается в бактерицидном и бактериостатическом действии по отношению к ряду микроорганизмов [20,23]. Следует отметить, что все указанные эффекты ГБО получены в экспериментальных исследованиях.…”

Section: Introductionunclassified

Parameters of the oxidative-reduction system of the homeostasis in female transplant patients with tumors of the reproductive system treated with hyperbaric oxygen therapy

Бабкина¹,

Хубутия²,

Левина³

et al. 2019

Transplantologiâ (Mosk.)

View full text Add to dashboard Cite

Introduction. Studies on the effects of hyperbaric oxygenation have often been represented as animal model experiments. Currently, the number of studies on the use of hyperbaric oxygen therapy in the post-transplant period in humans is growing. The need in investigating the efficacy of hyperbaric oxygen therapy in the postoperative period in female transplant patient with tumors of the reproductive system is dictated by time.The aim of the study was to evaluate the efficacy of hyperbaric oxygen therapy in the complex treatment of transplant patients at an early stage of the postoperative period.Material and methods. We have studied the course of an early postoperative period in 8 female transplant patients with reproductive system tumors treated in N.V. Sklifosovsky Research Institute for Emergency Medicine, using hyperbaric oxygenation. The hyperbaric oxygen therapy sessions were provided in a single-patient hyperbaric chamber at 1.2–1.6 ATA for 40 minutes. The status of the redox homeostasis system was assessed based on the data of the platinum electrode open circuit potential measured in blood plasma by using the potentiometric method; and the blood plasma antioxidant activity was assessed by cyclic voltammetry.Results. The analysis of the results showed that there was a direct relationship indicating the positive effect of hyperbaric oxygen therapy on the balance status of the pro- and antioxidant systems of the body, and on the improvement of blood counts.Conclusion. The early inclusion of hyperbaric oxygen therapy in the complex treatment of transplant patients with tumors of the reproductive system contributes to a more rapid recovery of pro- and antioxidant systems of the body, blood counts.

show abstract

Preliminary Report of the Safety and Efficacy of Hyperbaric Oxygen Therapy for Specific Complications of Lung Transplantation

Cited by 19 publications

References 26 publications

Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery

Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery

Hyperbaric oxygenation in transplantology

Parameters of the oxidative-reduction system of the homeostasis in female transplant patients with tumors of the reproductive system treated with hyperbaric oxygen therapy

Contact Info

Product

Resources

About