Prematuration of bovine oocytes with butyrolactone I: Effects on meiosis progression, cytoskeleton, organelle distribution and embryo development

Adona, Paulo Roberto; Pires, Pedro Ratto Lisboa; Quetglas, Maria Daniela; Schwarz, Kátia Regina Lancellotti; Leal, Cláudia Lima Verde

doi:10.1016/j.anireprosci.2007.07.002

Cited by 34 publications

(42 citation statements)

References 53 publications

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“…In fact, a recent work (Adona et al, 2008) has demonstrated that butyrolactone, a cdk inhibitor that selectively inhibits MPF like roscovitine does, reversibly blocked CG migration and partially blocked mitochondria translocation, demonstrating that MPF and/or MAPK can be implicated in organelle movement control. However, other studies (Vigneron et al, 2004) suggested that cytoplasmic maturation is not completely blocked during meiotic block and that other factors besides MPF could participate in this control.…”

Section: Discussionmentioning

confidence: 99%

“…However, several studies have recently demonstrated that prematuration of bovine oocytes in simple medium did not improve oocyte competence, but also did not cause major structural alterations in oocytes and embryos (Barretto et al, 2007;Adona et al, 2008). Then, it can be supposed that the addition of stimulatory components to the prematuration culture medium, such as hormones, could create a more suitable environment for promoting the developmental potential of the oocytes (Ponderato et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

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Meiotic inhibition of bovine oocytes in medium supplemented with a serum replacer and hormones: effects on meiosis progression and developmental capacity

Barretto

Castro

Garcia

et al. 2010

Zygote

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SummaryAiming to improve the developmental competence of bovine oocytes during meiotic block, this study evaluated the effects of a serum replacer (Knockout SR R ) and hormones (gonadotropins and estradiol) supplementation of prematuration medium (TCM119 with 0.5 mM IBMX [IBMX group] or 25 μM roscovitine [ROSC group]) on the kinetics of oocyte nuclear maturation and embryo development. Most IBMX and ROSC oocytes prematured for 8 h culture remained in the GV stage (70.3% and 73.1%, respectively; p > 0.05) similar to Control 8 h (63.5%) and to control immature oocytes (Control 0 h, 92.5%). After prematuration for 16 h, no oocytes remained in the GV stage at similar rates to those recently aspirated (p < 0.05); GV rates in ROSC (32.4%) were higher (p < 0.05) than in the Control 16 h group (8.6%), but similar (p > 0.05) to IBMX (9.7%). After in vitro maturation (IMV) for 24 h, metaphase II (MII) rates for oocytes prematured during 8 h were similar (p > 0.05) between control and treatments (65.0-71.7%). Similarly, MII rates oocytes prematured during 16 h were similar (p > 0.05) between all groups (45.9-60.4%). Cleavage rates (67.8-78.2%), embryonic development in day-7 (25.0-35.6%) and hatching rates in day-8 (2.5-11.3%) oocytes blocked during 8 h were similar for all groups (p > 0.05).Results indicate that addition of Knockout SR R and hormones to meiotic block culture with IBMX and roscovitine negatively affected meiotic arrest, but did not impair oocyte nuclear maturation and acquisition of developmental competence.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Meiotic inhibition of bovine oocytes in medium supplemented with a serum replacer and hormones: effects on meiosis progression and developmental capacity

Barretto

Castro

Garcia

et al. 2010

Zygote

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“…Microtubule (MT) and chromosome (CM) staining were performed according to the method previously described by Adona et al [3]. Briefly, at 2 h after warming, oocytes freed from cumulus cells were fixed in 3% paraformaldehyde supplemented with 0.6% Triton X-100 in mDPBS with 0.1% polyvinyl alcohol (PP) [37] for 30 min.…”

Section: Microtubule (Mt) and Chromosome (Cm) Stainingmentioning

confidence: 99%

Pretreatment of in vitro matured bovine oocytes with docetaxel before vitrification: Effects on cytoskeleton integrity and developmental ability after warming

et al. 2015

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“…Wang investigated butyrolactone I inhibits H1N1, the cell toxicity is lower at the same time, shows that the compound might be a candidate for antiviral flu drug. The effects of butyrolactone I on the prevention of germinal vesicle breakdown, changes of microtubular structures, and development of porcine and bovine oocytes was studied (11,12), but the inhibition effect is temporary and reversible (13). A large number of derivative of butyrolactone I (butyrolactone II-VII and its sulphuric acid derivatives) (9,(14)(15)(16)) also showed various biological activity, which highlights the value of these compounds.…”

Section: Three Fungal Strains Displayed Different Antimicrobial Activitymentioning

confidence: 99%

Fast identification of the antibacterial in Aspergillus species

Wang¹,

Duan

Yang

et al. 2017

Period Biol

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Abstract:Background Conclusions: Our study has significant scope on targeting antibacterial metabolites. The described method could also be used as a rapid and costeffective tool for screening other bioactivity products. As such, this article could offer a fast approach to isolate drug-lead compounds from microorganisms.IntroductIon A spergillus genus is well known for its medical and commercial importance (1). They are prolific producers of lifesaving drugs, devastating toxins, or mass produced industrial enzymes (2). Many clinically beneficial secondary metabolites are produced by Aspergillus genus, such as lovastatin, terrein, griseofulvin. Lovastatin, also known as mevinolin or monacolin K, is effective clinical drug used for reducing serum cholesterol and slowing the progression of atherosclerosis. Lovastatin and its related compounds inhibit cholesterol synthesis by inhibiting the rate-limiting step in cellular cholesterol biosynthesis (3). Terrein, one of Aspergillus major secondary metabolites has ecological, antimicrobial, antiproliferative and antioxidative activities (4). Some strains of Aspergillus can biosynthesize gluconic acid which is a bulk

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Prematuration of bovine oocytes with butyrolactone I: Effects on meiosis progression, cytoskeleton, organelle distribution and embryo development

Cited by 34 publications

References 53 publications

Meiotic inhibition of bovine oocytes in medium supplemented with a serum replacer and hormones: effects on meiosis progression and developmental capacity

Meiotic inhibition of bovine oocytes in medium supplemented with a serum replacer and hormones: effects on meiosis progression and developmental capacity

Pretreatment of in vitro matured bovine oocytes with docetaxel before vitrification: Effects on cytoskeleton integrity and developmental ability after warming

Fast identification of the antibacterial in Aspergillus species

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