2005
DOI: 10.1016/j.taap.2005.01.011
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Prenatal methylmercury exposure affects spatial vision in adult monkeys

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Cited by 38 publications
(35 citation statements)
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References 47 publications
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“…The study intended to mimic the immunization schedule in human neonates. Corroborating Magos's et al (1985) conclusions in the rat experimental model, this study (Burbacher et al 2005) also reported that levels of organic mercury were lower in the brains of infant monkeys exposed to thimerosal compared to those exposed orally to MeHg. The brain half-times (defined as the time it takes for the brain level of mercury to decrease by half) also differed.…”
Section: Mercury Clears From the Body Much Faster After The Administrsupporting
confidence: 55%
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“…The study intended to mimic the immunization schedule in human neonates. Corroborating Magos's et al (1985) conclusions in the rat experimental model, this study (Burbacher et al 2005) also reported that levels of organic mercury were lower in the brains of infant monkeys exposed to thimerosal compared to those exposed orally to MeHg. The brain half-times (defined as the time it takes for the brain level of mercury to decrease by half) also differed.…”
Section: Mercury Clears From the Body Much Faster After The Administrsupporting
confidence: 55%
“…Thus, ethylmercury appears to behave like MeHg with fecal excretion accounting for most of the elimination from the body. The absorption rate and initial distribution volume of total mercury are also reported to be generally similar after ethylmercury injections and oral MeHg exposure (Burbacher et al 2005). In other words, peak total blood mercury levels after a single exposure to either ethylmercury or MeHg are very similar, implying that the organic mercury compounds behave similarly in the early hours after exposure.…”
Section: Mercury Clears From the Body Much Faster After The Administrmentioning
confidence: 84%
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“…Studies in monkeys showed that developmental as well as post-natal MeHg exposure could accelerate the impairment in auditory functions observed with ageing (Rice 1998;Rice and Gilbert 1992). Prenatal MeHg exposure has also shown to affect visual contrast sensitivity in adult monkeys (Burbacher et al 2005). In a review of the contribution of animal studies to the understanding the neurodevelopmental toxicity of MeHg, Castoldi et al suggest that there is a need to include the ''quality of aging'' as an additional endpoint in toxicity studies on MeHg (Castoldi et al 2008).…”
Section: Discussionmentioning
confidence: 99%
“…Quando a exposição ocorre durante o desenvolvimento embrionário, os prejuízos nas funções visuais espaciais tornam-se permanentes na idade adulta (Burbacher, Grant, Mayfield, Gilbert, & Rice, 2005).…”
Section: Mercúrio No Sistema Visualunclassified