“…The multidimensional devices generally require expensive instrumentation and highly skilled operators, which made them impractical for detection of analytes in the rural and underdeveloped areas. To overcome these drawbacks, colorimetric sensor arrays are extremely attractive because they can be easily read out by a simple UV À Vis absorption spectrophotometer or even with the naked eye (Askim et al, 2013;Feng et al, 2010;Janzen et al, 2006;Li et al, 2012;Lim et al, 2009;Lin et al, 2011;Musto et al, 2009;Rakow et al, 2005;Rakow and Suslick, 2000;Suslick et al, 2010;Yang et al, 2013). For example, Zhao et al designed simple colorimetric biosensors using of enzymatic cleavage of DNA on AuNPs for the detection of metal ions and sensing enzyme activities (Zhao et al, 2008).…”