Preparation and Characterization of Antibacterial Dental Resin with UDMQA‐12

Abstract

In this study, urethane methacrylate quaternary ammonium compound (UDMQA-12) was used to partially replace 2,2-bis[4-(2-hydroxy-3-methacryloyloxypropyl)-phenyl]propane (Bis-GMA) as the base compound of dental resin system. Double bond conversion, polymerization shrinkage, flexural strength (FS) and flexural modulus (FM), water sorption (WS) and water solubility (WSL), and antibacterial activity of all experimental resins were investigated. Bis-GMA/triethyleneglycol dimethacrylate resin without UDMQA-12 was used as a control group. Results showed that UDMQA-12 had no negative influence on the double bond conversion of the resin, but polymerization shrinkage, FS, and FM decreased with the increasing of UDMQA-12 concentration, whereas WS and WSL increased with it. UDMQA-12-containing polymer showed antibacterial activity when concentration of UDMQA-12 was 30% or more. C 2013 Wiley Periodicals, Inc. Adv Polym Technol 2014, 33, 21395; View this article online at wileyonlinelibrary.com.

Size Dependence of Particulate Calcium Phosphate Fillers in Dental Resin Composites

“…A common dental resin composite often consists of three components, namely, the mixture of resin monomers, photoinitiators, and inorganic fillers. In this study, a frequently used formulation of BT resin was employed, , which comprised Bis-GMA and TEGDMA as the resin monomers and DMAEMA and CQ as the photoinitiator system. Although enormous inorganic fillers have been integrated and studied as in dental composites, remineralizing CaP fillers have drawn much more attention due to their inhibitory nature against demineralization, as well as potential of remineralization at the composite–tooth interface .…”

Physicochemical Properties of Novel Copolymers of Quaternary Ammonium UDMA Analogues, Bis-GMA, and TEGDMA

“…Various QAMs have been described in the literature, including 2-(dimethylamino)ethyl methacrylate derivatives with chloride [ 7 , 8 , 9 ], bromide [ 10 , 11 , 12 , 13 , 14 , 15 ], and iodide [ 16 , 17 ] counter ions, quaternary ammonium derivative of bisphenol A glycerolate dimethacrylate [ 18 ], and fully aliphatic [ 19 ] and cycloaliphatic [ 20 , 21 ] urethane-dimethacrylates. Such QAMs represent potential antibacterial components of dental composites because they offer high antibacterial activity against various strains, including Streptococcus mutans [ 4 , 5 , 10 , 13 , 14 , 15 , 18 , 20 , 21 ], Staphylococcus aureus [ 5 , 18 ], and Escherichia coli [ 18 ]. However, the well-known QAMs induce a loss of mechanical properties and an increase in the amount of water absorbed by the material and in residual fraction release [ 4 , 5 , 10 , 13 , 14 , 15 , 18 , 19 , 21 , 22 ].…”

“…Such QAMs represent potential antibacterial components of dental composites because they offer high antibacterial activity against various strains, including Streptococcus mutans [ 4 , 5 , 10 , 13 , 14 , 15 , 18 , 20 , 21 ], Staphylococcus aureus [ 5 , 18 ], and Escherichia coli [ 18 ]. However, the well-known QAMs induce a loss of mechanical properties and an increase in the amount of water absorbed by the material and in residual fraction release [ 4 , 5 , 10 , 13 , 14 , 15 , 18 , 19 , 21 , 22 ]. Nevertheless, the field of antibacterial dimethacrylates has continued to evolve, and there are still many possibilities to design new compounds with chemical structures that are suitable for obtaining dental composites with appropriate physicochemical, mechanical, and antibacterial characteristics.…”

Synthesis and Characterization of Novel Quaternary Ammonium Urethane-Dimethacrylate Monomers—A Pilot Study

“…The UDMQA/TEGDMA 50/50 wt.% polymers showed satisfactory antibacterial activity against S. mutans, a high degree of conversion, and low polymerization shrinkage. However, their flexural strength, modulus, water sorption, and water solubility worsened [24].…”