2012
DOI: 10.1166/jbn.2012.1454
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Preparation and Characterization of Monodisperse Core–Shell Fe<SUB>3</SUB>O<SUB>4</SUB> @SiO<SUB>2</SUB> Microspheres and Its Application for Magnetic Separation of Nucleic Acids from <I>E. coli</I> BL21

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Cited by 84 publications
(25 citation statements)
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“…[24][25][26] Since loaded drugs can be easily dissociated from the particles after uptake into cells, 27 28 the nanoparticles have been widely used in both clinics and academic researches. [29][30][31][32][33][34] In an effort to reduce drug resistance and MM relapse, we exploited an anti-ABCG2 monoclonal antibody (McAb) to target directly at ABCG2 on MM CSCs. We found that the combination of PTX with -Fe 2 O 3 @DMSA magnetic nanoparticles (MNPs) and McAb achieved a significant inhibition of MM CSCs in vitro, and their tumorigenicity in vivo.…”
Section: Introductionmentioning
confidence: 99%
“…[24][25][26] Since loaded drugs can be easily dissociated from the particles after uptake into cells, 27 28 the nanoparticles have been widely used in both clinics and academic researches. [29][30][31][32][33][34] In an effort to reduce drug resistance and MM relapse, we exploited an anti-ABCG2 monoclonal antibody (McAb) to target directly at ABCG2 on MM CSCs. We found that the combination of PTX with -Fe 2 O 3 @DMSA magnetic nanoparticles (MNPs) and McAb achieved a significant inhibition of MM CSCs in vitro, and their tumorigenicity in vivo.…”
Section: Introductionmentioning
confidence: 99%
“…In sum, the whole process consists of five major steps: lysis, MNPs-nucleic acids binding, washing, elution and collection. [21][22] In a typical extraction, for 200 L of sample (E.coli culture, yeast culture, whole blood, or virus serum), 200 L of 6 M guanidine hydrochloride lysis solution and 10 L of Proteinase K (20 mg/mL) was added. The tube was shaken by gentle inversion for two or three times and incubated at room temperature for a minute.…”
Section: Extraction and Measurement Of Genomicmentioning
confidence: 99%
“…It is evident that supported lipid bilayers (SLB) retain many of the characteristics of natural cell membranes such as lateral fluidity, 6 7 incorporation of proteins, 4 8 phase separation, 9 and impermeability to ionic species. 10 On the other hand, the magnetic nanoparticles (MNPs) [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] can be used as local heat producer by forcing alternating current magnetic fields (ACMF). The MNPs such as -Fe 2 O 3 for hyperthermia were investigated a lot.…”
Section: Introductionmentioning
confidence: 99%