Preparation, characterization and release of amoxicillin from cellulose acetate and poly(vinyl pyrrolidone) coaxial electrospun fibrous membranes

Castillo‐Ortega, M. M.; Nájera-Luna, A. L.; Rodríguez-Félix, Dora Evelia; Encinas, José Carmelo; Romero‐García, Jorge; Herrera‐Franco, Pedro J.

doi:10.1016/j.msec.2011.08.009

Cited by 69 publications

(30 citation statements)

References 23 publications

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“…Its good properties stimulated research focused on the generation of CA structures (membranes, foams, microparticles etc.) that contain bioactive compounds [4,5,14,[28][29][30]. These CA structures can be produced with methods like solvent casting, electrospinning, supercritical phase separation, and so on and used for controlled delivery of additives [14,[28][29][30].…”

Section: Introductionmentioning

confidence: 99%

“…that contain bioactive compounds [4,5,14,[28][29][30]. These CA structures can be produced with methods like solvent casting, electrospinning, supercritical phase separation, and so on and used for controlled delivery of additives [14,[28][29][30]. CA foams with scopolamine and CA films with pepper essential oil produced by solvent casting method can be used for skin treatment [28] and as active food packaging [29], respectively.…”

Section: Introductionmentioning

confidence: 99%

“…CA foams with scopolamine and CA films with pepper essential oil produced by solvent casting method can be used for skin treatment [28] and as active food packaging [29], respectively. CA membranes produced by electrospinning and subsequent immersion in amoxicillin solution can have gastrointestinal application [30]. CA microparticles, nanofibrous networks, and cellular membrane with nonsteroidal anti-inflammatory drug ibuprofen produced by supercritical fluid technology were reported for tissue engineering applications [14].…”

Section: Introductionmentioning

confidence: 99%

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Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Milovanović

Adamović

Aksentijević

et al. 2017

International Journal of Polymer Science

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Supercritical CO 2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50 ∘ C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6-60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0-33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled delivery applications.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Milovanović

Adamović

Aksentijević

et al. 2017

International Journal of Polymer Science

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“…In addition, the release amount of curcumin from the curcumin-loaded electrospun CA fiber mats was greater than that from films at any given immersion time point in both investigated techniques [30]. In 2011, the fibrous membranes of CA, poly(vinylpyrrolidone) (PVP), and composite membranes of these polymers were fabricated by coaxial electrospinning [46]. Amoxicillin is in a class of antibiotics called penicillin.…”

Section: Drug Delivery Systemsmentioning

confidence: 99%

Applications of Cellulose Acetate Nanofiber Mats

Suwantong

Supaphol

2014

Handbook of Polymer Nanocomposites. Processing, Performance and Application

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“…The spinning module can create continuous primary mechanical vibration in polymeric solution, and the creation of turbulence in polymeric solution helps in some way to produce primary jets [33]. The cellulosic nanofiber is employed in a variety of applications in different areas including optical [40], electronic [41], medical [42] engineering, and membrane technology [43]. One of the extremely important applications of nanofibers has been proposed for filtration technology which extensively increases the efficiency and dramatically reduce the pressure drop during the separation process [44,45].…”

Section: Introductionmentioning

confidence: 99%

A feasibility study on semi industrial nozzleless electrospinning of cellulose nanofiber

et al. 2015

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The current study focuses on the production of cellulose nanofiber through semi-industrial nozzleless electrospinning process. The cellulose biopolymer used for spinning process was extracted from rice straw as renewable, abundant, and inexpensive natural resource. The electrospinning device comprising one needle is extremely inefficient because of low productivity level of about 0.3 g/h. Thus, using the nozzleless electrospinning system guarantees the high productivity of nanofiber web for diverse applications. The successful electrospinning process is accomplished through systematic control of the surface tension, viscosity, and electric conductivity of aqueous solutions of cellulose. Moreover, a design expert software was used for providing experimental plan for the investigation of the influence of the operational conditions on the spinning properties of the selected solution. The polyvinyl alcohol with a weight ratio of 60 % relative to cellulose content was used as a biocompatible polymer to facilitate electrospinning process for producing the aqueous cellulose solution of 0.63 wt%. Based on the scanning electron microscopy images, and various selected parameters, namely, the drum rotation rate of 9 rpm, high voltage range of ±55 kV, the spinning temperature of 41°C, and 10-cm distance between drum and collector an average diameter of 89 ± 1 nm was arrived. The composite nanofibers used for filter production and their performance were evaluated by porosity analysis and permeability tests. Results show the negative impact of the weak mechanical strength as an obstacle in Penetration test. (It promotes by higher electrospinning time and reaching proper stiffness in web layer.) The permeability tests show a maximum value of 3.5 cm 3 /cm 2 /s at the maximum pressure of 120 Pa.

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Preparation, characterization and release of amoxicillin from cellulose acetate and poly(vinyl pyrrolidone) coaxial electrospun fibrous membranes

Cited by 69 publications

References 23 publications

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Applications of Cellulose Acetate Nanofiber Mats

A feasibility study on semi industrial nozzleless electrospinning of cellulose nanofiber

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