Preparation of a chemiluminescence sensor for multi-detection of benzimidazoles in meat based on molecularly imprinted polymer

Cai, Yong; He, Xin; Cui, Peng; Liu, Jing; Li, Zhao Bin; Jia, Bing; Zhang, Teng; Wang, Jian Ping; Yuan, Wan Zhe

doi:10.1016/j.foodchem.2018.12.052

Cited by 38 publications

(10 citation statements)

References 37 publications

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“…MD-based investigations of other aspects of the pre-polymerization stage include studies of the structural stability of protein epitopes for template screening [ 414 , 415 ], mapping potential monomer interaction sites of a protein target, followed by docking of acrylamide-derived monomers and post-docking interaction energy calculations [ 416 ], studies of template interactions with Dengue virus as a support matrix to create larger binding sites [ 417 ], a series of reports attempting to correlate structural and physical properties of dummy templates and ligands with rebinding properties [ 418 , 419 , 420 , 421 , 422 , 423 , 424 , 425 , 426 ] and coarse-grained simulations studying the effect of composition on material properties and template interaction [ 427 ]. Additionally, large-scale MD simulations were performed in an attempt to mimic chromatography in a virtual capillary [ 428 ].…”

Section: The Pre-polymerization Stagementioning

confidence: 99%

The Use of Computational Methods for the Development of Molecularly Imprinted Polymers

et al. 2021

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Recent years have witnessed a dramatic increase in the use of theoretical and computational approaches in the study and development of molecular imprinting systems. These tools are being used to either improve understanding of the mechanisms underlying the function of molecular imprinting systems or for the design of new systems. Here, we present an overview of the literature describing the application of theoretical and computational techniques to the different stages of the molecular imprinting process (pre-polymerization mixture, polymerization process and ligand–molecularly imprinted polymer rebinding), along with an analysis of trends within and the current status of this aspect of the molecular imprinting field.

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Section: The Pre-polymerization Stagementioning

confidence: 99%

The Use of Computational Methods for the Development of Molecularly Imprinted Polymers

et al. 2021

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“…Optimization of experimental conditions.-To achieve the maximum effect on the as-prepared ECL sensor, some parameters (the elec- trode material dosage and concentration of luminol) were optimized. 47 Fig. S1 reveals that the optimal material capacity of electrode is 10 μL, but large excess of Fe/N-C causes overloading at the electrode surface resulting in the decrease of the current electron transfer rate affecting the output of the reaction signal.…”

Section: Electrocatalytic Activity and Mechanism Exploration Of Fe/n-...mentioning

confidence: 99%

Enhanced Electrochemiluminescence Detection for Hydrogen Peroxide Using Peroxidase-Mimetic Fe/N-Doped Porous Carbon

Tian¹,

Tan²,

Dang³

et al. 2019

J. Electrochem. Soc.

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Detecting hydrogen peroxide (H 2 O 2 ) is obviously indispensable on account of its low toxicity and wide application, and it is still a challenge for developing highly sensitive and selective electrochemiluminescence (ECL) sensors based on the noble metal-free electrode. Hence, we designed an accurate ECL sensor for detecting trace H 2 O 2 based on N-doped porous carbon containing Fe (Fe/N-C) nanocomposites, which were successfully synthesized by pyrolysis of NH 2 -MIL-101(Fe) metal-organic framework (MOF). Fe/N-C nanocomposite significantly improved the electron transfer process and enhanced the catalytic activity of ECL sensor for trace H 2 O 2 detection. Fe/N-C nanocomposite significantly contributed in the conversion of H 2 O 2 to superoxide radical, followed by the oxidation of luminal which enhanced the electrochemical luminescence signal. Predictably, the ECL sensing strategy at Fe/N-C nanocomposite electrode showed a satisfying linear range from 1 nM to 300 nM for H 2 O 2 detection with limit of detection (LOD) as 0.93 nM (signal to noise ratio (S/N) = 3). Also, the ECL sensor was used to detect H 2 O 2 in real water samples and renal epithelial 293T cells, which justified great promise for the practical ECL detection of H 2 O 2 .

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“…In the first decades, the development and application of MIPs were mainly focused on separation and extraction techniques. Nowadays, MIPs are used in a wide variety of applications, including sample preparation (e.g., solid phase extraction) [ 12 , 13 ] chromatographic separation [ 14 ], chemical sensing [ 15 ], and drug delivery [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Polymers Combined with Electrochemical Sensors for Food Contaminants Analysis

et al. 2021

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Detection of relevant contaminants using screening approaches is a key issue to ensure food safety and respect for the regulatory limits established. Electrochemical sensors present several advantages such as rapidity; ease of use; possibility of on-site analysis and low cost. The lack of selectivity for electrochemical sensors working in complex samples as food may be overcome by coupling them with molecularly imprinted polymers (MIPs). MIPs are synthetic materials that mimic biological receptors and are produced by the polymerization of functional monomers in presence of a target analyte. This paper critically reviews and discusses the recent progress in MIP-based electrochemical sensors for food safety. A brief introduction on MIPs and electrochemical sensors is given; followed by a discussion of the recent achievements for various MIPs-based electrochemical sensors for food contaminants analysis. Both electropolymerization and chemical synthesis of MIP-based electrochemical sensing are discussed as well as the relevant applications of MIPs used in sample preparation and then coupled to electrochemical analysis. Future perspectives and challenges have been eventually given.

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Preparation of a chemiluminescence sensor for multi-detection of benzimidazoles in meat based on molecularly imprinted polymer

Cited by 38 publications

References 37 publications

The Use of Computational Methods for the Development of Molecularly Imprinted Polymers

The Use of Computational Methods for the Development of Molecularly Imprinted Polymers

Enhanced Electrochemiluminescence Detection for Hydrogen Peroxide Using Peroxidase-Mimetic Fe/N-Doped Porous Carbon

Molecularly Imprinted Polymers Combined with Electrochemical Sensors for Food Contaminants Analysis

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