Preparation of a novel sulfated glycopeptide complex and inhibiting L1210 cell lines property in vitro

Characterization and antioxidant activity of two low-molecular-weight polysaccharides purified from the fruiting bodies of Ganoderma lucidum

“…Similar anomeric signals were also observed in the anomeric region of GLP L 2 (Fig. 3B), while there was an extra anomeric signal at 100.5 ppm which belonged to →6)-␣-Galp-(1→ unit [26]. The signals at around 85-87 ppm (85.2, 86.9, and 87.5 ppm in GLP L 1, 86.5, 86.7, and 87.1 ppm in GLP L 2, Fig.…”

“…3A and B) were attributed to the C-3 of →3)-␤-Glcp-(1→ or →3,6)-␤-Glcp-(1→ units in different chemical atmospheres, while that at 77.4 ppm in GLP L 1 and 77.1 ppm in GLP L 2 corresponded to C-3 of the nonreducing end units [28]. The signals at 81.7 ppm in GLP L 1 and 81.2 ppm in GLP L 2 arose from C-4 of →4,6)-␤-Glcp-(1→ units, while that at 78.2 ppm in GLP L 1 and 78.4 ppm in GLP L 2 corresponded to C-4 of →4)-␤-Glcp-(1→ units [26,30]. Resonances at 68.8 or 69.5 ppm in GLP L 1 and 68.5 or 69.1 ppm in GLP L 2 arose from →6)-␤-Glcp-(1→ and →3,6)-␤-Glcp-(1→ or →4,6)-␤-Glcp-(1→ units, while the peak at 69.7 ppm in GLP L 2 corresponded to the C-6 of →6)-␣-Galp-(1→ unit [26,28].…”

“…The 13 C NMR spectrum of GLP L 1 showed four anomeric signals at around 105 ppm: one at 105.4 ppm that corresponded to nonreducing end units, the one at 105.1 ppm could be assigned to →3)-␤-Glcp-(1→ and →3,6)-␤-Glcp-(1→ units while the one at 105.3 ppm was due to →4)-␤-Glcp-(1→ unit and →4,6)-␤-Glcp-(1→ and the other one at 104.9 ppm could be assigned to C-1 of →6)-␤-Glcp-(1→ unit (Fig. 3A) [26,28,29]. Similar anomeric signals were also observed in the anomeric region of GLP L 2 (Fig.…”

Application of marine biomaterials for nutraceuticals and functional foods

“…The sulfated polysaccharides/glycoproteins are found to act as antitumor agents (36). More than 200 polysaccharides/ glycoconjugates have been isolated from Ganoderma lucidum, which is a well-known traditional Chinese medicine (37,38).…”

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“…The Bax/Bcl-2 ratio was also increased in GA-treated HeLa cells. An in vitro study on mouse lymphocytic leukemia cancer revealed that mainly LZ-D4, a native glycopepetide and sulphonated derivative purified from G.lucidum were effective against cancer 37 .…”