Preparation of Three-Dimensional Graphene Oxide Electric-Field/Temperature-Sensitive Hydrogels and Transdermal-Controlled Release Drug Delivery Study

Jia, Kai; Chen, Anqi; Meng, Dong; Li, Li; Liu, Yu

doi:10.1007/s11664-023-10307-y

J. Electron. Mater.

2023

DOI: 10.1007/s11664-023-10307-y

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Preparation of Three-Dimensional Graphene Oxide Electric-Field/Temperature-Sensitive Hydrogels and Transdermal-Controlled Release Drug Delivery Study

Kai Jia

Anqi Chen

Dong Meng

et al.

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Cited by 4 publications

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Study on the gelation and sustained release effect of the thermosensitive material TPGS₁₀₀₀

He,

Yang,

Qian

et al. 2023

J of Applied Polymer Sci

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Polyethylene glycol 1000 vitamin E succinate (TPSG1000) was commonly used as absorption promoter, solubilizer, and emulsifier in drug delivery systems. In addition, TPGS1000 possessed thermosensitivity and gelling property that were not extensively studied. Hence, TPGS1000 was synthesized by Collnot method, characterized, evaluated for gelling property, and applied as the thermosensitive carrier in the study. Thin‐layer chromatography, Fourier transform infrared spectroscopy, and high‐performance liquid chromatography methods proved that the TPGS1000 was successfully synthesized. Under the condition of 4.5% sodium sulfate, 12% TPGS1000 could rapidly form stable hydrogels at 37°C. In addition, the gelling time tends to shorten with temperature increasing. It is worth noting that TPGS1000 as the carrier for loading doxorubicin displayed significant sustained release behavior. In conclusion, the study laid foundation for the application and further research of TPGS1000 in thermosensitive gel drug delivery system and provides a novel material for thermosensitive gel preparations.

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Study on the gelation and sustained release effect of the thermosensitive material TPGS₁₀₀₀

He,

Yang,

Qian

et al. 2023

J of Applied Polymer Sci

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show abstract

Compound Model of Twisted and Coiled Polymer Actuators Describing Relationship Between Output Force and Excitation Current

Wang,

Zhang,

et al. 2024

J. Electron. Mater.

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Pharmaceutical chitosan hydrogels: A review on its design and applications

Chellathurai,

Chung,

Hilles

et al. 2024

International Journal of Biological Macromolecules

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Preparation of Three-Dimensional Graphene Oxide Electric-Field/Temperature-Sensitive Hydrogels and Transdermal-Controlled Release Drug Delivery Study

Cited by 4 publications

References 25 publications

Study on the gelation and sustained release effect of the thermosensitive material TPGS₁₀₀₀

Study on the gelation and sustained release effect of the thermosensitive material TPGS₁₀₀₀

Compound Model of Twisted and Coiled Polymer Actuators Describing Relationship Between Output Force and Excitation Current

Pharmaceutical chitosan hydrogels: A review on its design and applications

Contact Info

Product

Resources

About

Preparation of Three-Dimensional Graphene Oxide Electric-Field/Temperature-Sensitive Hydrogels and Transdermal-Controlled Release Drug Delivery Study

Cited by 4 publications

References 25 publications

Study on the gelation and sustained release effect of the thermosensitive material TPGS1000

Study on the gelation and sustained release effect of the thermosensitive material TPGS1000

Compound Model of Twisted and Coiled Polymer Actuators Describing Relationship Between Output Force and Excitation Current

Pharmaceutical chitosan hydrogels: A review on its design and applications

Contact Info

Product

Resources

About

Study on the gelation and sustained release effect of the thermosensitive material TPGS₁₀₀₀

Study on the gelation and sustained release effect of the thermosensitive material TPGS₁₀₀₀