Preservation of Pregnancy in a Patient With Acute Abdominal Pain Secondary to Advanced and Hemorrhagic Yolk Sac Tumor of the Right Ovary

Viana, Luciano S.; Tsunoda, Audrey Tieko; Nunes, João; Fregnani, José Humberto Tavares Guerreiro; Vieira, Marcelo Andrade da Costa; Borges, Ana Karina Nascimento; Andrade, Carlos Eduardo Mattos da Cunha; Serrano, Sergio

doi:10.1200/jco.2011.35.9554

Cited by 7 publications

(5 citation statements)

References 16 publications

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“…Malignant ovarian germ cell tumors are classified as dysgerminoma and non-dysgerminoma. The latter commonly includes neoplasms that contain teratoma, embryonal, yolk sac tumor, and/or choriocarcinoma elements [6]. Ovarian yolk sac tumor (OYST) also known as endodermal sinus tumor, is a highly malignant germ cell tumor and is highly aggressive whose fiveyear survival rates are unclear because of differing stages [7].…”

Section: Discussionmentioning

confidence: 99%

Primary cervical choriocarcinoma with germ cell tumor: a case report with literature review

Lü¹,

Wu²,

Yue³

et al. 2019

EJGO

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Background: Gestational trophoblastic diseases (GTD) is a series of malignant cancer can be subdivided in pregnancy-associated disease or non-pregnancy choriocarcinoma. The latter among the GTD is extremely rare, particularly primary cervical choriocarcinoma. Case Report: The authors present a case of primary cervical choriocarcinoma with germ cell tumor which is rarely reported. A 46-yearold female visited Beijing Obstetrics and Gynecology hospital because of irregular vaginal bleeding who had undergone radical cervical cancer surgical treatment. After surgery, her symptoms were not visibly changed and the result of pathology suggested cervical cancer. Finally, the authors confirmed its non-gestational origin with ovarian yolk sac tumor by immunohistochemical staining and the level of serum beta-hCG. Fortunately, multiple courses of chemotherapy with BEP regimen were effective for this case. Conclusion: During the course of diagnosis and therapy, immunohistochemical staining and the level of beta-hCG are useful. We could distinguish The tissue origin of this tumor with cervical cancer was distinguished and early diagnosis contributed to the therapy of this disease.

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Section: Discussionmentioning

confidence: 99%

Primary cervical choriocarcinoma with germ cell tumor: a case report with literature review

Lü¹,

Wu²,

Yue³

et al. 2019

EJGO

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“…Table 3 summarizes the reported 193 patients diagnosed with NEOC, and treated with chemotherapy during pregnancy. Among 145 documented cases of germ cell tumours, histopathology was compatible with EST in 52 patients [1] , [4] , [40] , [49] , [76] , [77] , [79] , [81] , [87] , [88] , dysgerminoma in 45 [4] , [8] , [40] , [75] , [80] , [87] , immature teratoma in 24 [4] , [40] , [76] , [82] , [87] , [89] , whereas mixed elements were revealed in 13 patients [1] , [40] , [78] , [87] , respectively. Platinum-bleomycin based chemotherapy was administered in 68 patients.…”

Section: Non-epithelial Ovarian Cancer In Pregnancymentioning

confidence: 94%

“…Similarly, etoposide and cisplatin (EP) was administered in five patients with gestational ovarian malignant germ cell tumours. IUGR with either low birth weight or oligohydramnios was detected in two cases ( Table 1 ) [1] , [79] , [80] . The second infant was delivered with anaemia and thrombocytopenia [79] .…”

Section: Chemotherapy In Gestational Ovarian Cancermentioning

confidence: 99%

“…IUGR with either low birth weight or oligohydramnios was detected in two cases ( Table 1 ) [1] , [79] , [80] . The second infant was delivered with anaemia and thrombocytopenia [79] . There is also potentially increased risk of secondary leukemia related to etoposide utilization.…”

Section: Chemotherapy In Gestational Ovarian Cancermentioning

confidence: 99%

“…Platinum-bleomycin based chemotherapy was administered in 68 patients. As far as recognized fetal growth abnormalities is concerned, IUGR was relatively common (14.5%) [76] , [79] , [80] , [87] . Spontaneous abortion was experienced in five cases (3.4%) [40] , [87] , whereas ventriculomegaly [1] , [77] , [88] and respiratory distress syndrome [1,39/1,40] were identified in three and two cases, respectively.…”

Section: Non-epithelial Ovarian Cancer In Pregnancymentioning

confidence: 99%

See 2 more Smart Citations

A review on pregnancy complicated by ovarian epithelial and non-epithelial malignant tumors: Diagnostic and therapeutic perspectives

Boussios

Moschetta

Tatsi

et al. 2018

Journal of Advanced Research

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Efficacy and Safety of Platinum-Based Chemotherapy for Ovarian Cancer During Pregnancy: A Systematic Review and Meta-Analysis

Pei

Gou

et al. 2021

Oncol Ther

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Introduction:Based on the available data on ovarian cancer during pregnancy, we performed a review and meta-analysis to evaluate the efficacy and safety of platinum-based chemotherapy against ovarian cancer during pregnancy. Methods: We systematically searched three databases including the PubMed, Embase, and Cochrane Library databases for articles published from January 1986 to December 2020 using the following terms: ''ovarian tumors OR ovarian carcinoma OR adnexal masses OR ovarian cancer'' AND ''pregnancy'' AND ''chemotherapy.'' Two authors (Yaping Pei and Yuanfeng Gou) independently searched the literature and extracted data from each eligible study. The outcome measures were overall survival (OS) and progression-free survival (PFS).

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Preservation of Pregnancy in a Patient With Acute Abdominal Pain Secondary to Advanced and Hemorrhagic Yolk Sac Tumor of the Right Ovary

Cited by 7 publications

References 16 publications

Primary cervical choriocarcinoma with germ cell tumor: a case report with literature review

Primary cervical choriocarcinoma with germ cell tumor: a case report with literature review

A review on pregnancy complicated by ovarian epithelial and non-epithelial malignant tumors: Diagnostic and therapeutic perspectives

Efficacy and Safety of Platinum-Based Chemotherapy for Ovarian Cancer During Pregnancy: A Systematic Review and Meta-Analysis

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