Prevalence and drug susceptibility pattern of Salmonella isolates from apparently healthy slaughter cattle and personnel working at the Jimma municipal abattoir, south-West Ethiopia

Takele, Samson; Woldemichael, Kifle; Gashaw, Mulatu; Tassew, Haimanot; Yohannes, Moti; Abdissa, Alemseged

doi:10.1186/s40794-018-0072-6

Cited by 20 publications

(27 citation statements)

References 17 publications

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“…During this period, 6 full articles and three published abstracts representing 11 datasets were retrieved using the search engines (67–75). The majority of these studies were reported from Africa (67, 68, 70–74) except for two studies from Europe (69) and South America (75). Among the total of 5,868 cattle examined, 9.2% (554/6018), which is nearly equal to the pooled prevalence estimate, were reported to be positive for Salmonella species with different serotypes.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Serotype Diversity of Salmonella in Apparently Healthy Cattle: Systematic Review and Meta-Analysis of Published Studies, 2000–2017

et al. 2019

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Salmonellosis is a leading cause of foodborne illnesses in humans with cattle being one of the reservoirs for Salmonella . We estimated a pooled prevalence of Salmonella in apparently healthy cattle and examined serotype diversity through systematic review and meta-analysis of studies published between 2000 and 2017. Peer reviewed publications reporting the prevalence of Salmonella in cattle were searched through five electronic databases (PubMed, Google scholar, Agricola, Scopus, CAB direct) and through manual search. We obtained 71 publications with 75 datasets consisting a total of 52,766 animals examined and 5,010 Salmonella positive cattle from 29 countries in six continents (except from Antarctica). Pooled prevalence of Salmonella in cattle was 9% (95% confidence interval: 7–11%). Significantly high heterogeneity ( I 2 = 98.7%, P < 0.01) was observed among all studies as well as within continents. Prevalence varied from 2% (Europe) to 16% (North America). Overall, 143 different serotypes were reported with the most diverse serotypes being reported from Africa (76 different serotypes) followed by North America (49 serotypes). The 10 most frequently reported serotypes (Montevideo, Typhimurium, Kentucky, Meleagridis, Anatum, Cerro, Mbandaka, Muenster, Newport, and Senftenberg) accounted for 65% of the isolates for which specific serotype information was reported. Salmonella Montevideo and S . Dublin are the most frequently reported serotypes in North America and Europe, respectively, while S . Typhimurium was the most frequent in Africa, Asia and Australasia. Our results indicated variability both in the prevalence and serotype diversity of Salmonella in cattle across continents. Although all Salmonella serotypes are potentially pathogenic to humans, five (Montevideo, Typhimurium, Anatum, Mbandaka, and Newport) of the top 10 serotypes identified in this study are among the serotypes most commonly associated with clinical illnesses in humans.

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Section: Discussionmentioning

confidence: 99%

Prevalence and Serotype Diversity of Salmonella in Apparently Healthy Cattle: Systematic Review and Meta-Analysis of Published Studies, 2000–2017

et al. 2019

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“…A total of 1475 Salmonella serovars were isolated from 34 included studies. Of these, 430 were only from animal products [ 22 – 24 , 26 , 32 , 36 , 37 , 40 , 47 , 48 , 53 ], 331 were only from animal specimens [ 25 , 27 , 30 , 43 , 45 , 46 , 51 , 52 ], 249 were from human/animal/animal product [ 28 , 29 , 34 , 35 , 41 , 49 , 54 ] and the rest were from others samples [ 21 , 31 , 33 , 38 , 39 , 42 , 44 , 50 ] as presented on Table 1 . Based on the region, the majority of the isolates (n = 487) were from Oromia region followed by Addis Ababa (n = 369), SNNRP (N = 159) and Amhara (n = 173) [ 26 , 50 , 52 ] ( Fig 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, seven studies included human, animal, and animal product specimens, three studies included both animal and animal products and the rest three included both human and animal products Table 1. A total of 1475 Salmonella serovars were isolated from 34 included studies. Of these, 430 were only from animal products [22-24, 26, 32, 36, 37, 40, 47, 48, 53], 331 were only from animal specimens [25,27,30,43,45,46,51,52], 249 were from human/animal/animal product [28,29,34,35,41,49,54] and the rest were from others samples [21,31,33,38,39,42,44,50] as presented on Table 1. Based on the region, the majority of the isolates (n = 487) were from Oromia region followed by Addis Ababa (n = 369), SNNRP (N = 159) and Amhara (n = 173) [26,50,52] (Fig 2).…”

Section: Plos Onementioning

confidence: 99%

Epidemiology of streptomycin resistant Salmonella from humans and animals in Ethiopia: A systematic review and meta-analysis

et al. 2020

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Background Streptomycin is used as an epidemiological marker in monitoring programs for antimicrobial resistance in Salmonella serovars and indicates the presence of pentaresistance. However, comprehensive data on streptomycin resistant Salmonella among human, animal, and animal products is lacking in Ethiopia. In this review, we aimed to assess heterogeneity and pooled proportion of Salmonella serovars to streptomycin resistance among human, animal and animal products in Ethiopia. Methods We conducted a systematic review and meta-analysis of published literature from Ethiopia. We used the MEDLINE/ PubMed, Embase, Cochrane Library, and Google Scholar databases to identify genetic and phenotypic data on Salmonella isolates. To determine the heterogeneity and pooled proportion, we used metaprop commands and the random-effects model. Relative and cumulative frequencies were calculated to describe the overall preponderance of streptomycin resistance isolates after arcsine-transformed data. Metan funnel and meta-bias using a begg test were performed to check for publication bias. Results Overall, we included 1475 Salmonella serovars in this meta-analysis. The pooled proportion of streptomycin resistance was 47% (95% CI: 35–60%). Sub-group analysis by target population showed that the proportion of streptomycin resistance in Salmonella serovars was 54% (95% CI: 35–73%) in animal, 44% (95% Cl: 33–59%) in humans and 39% (95% CI: 24–55%) in animals products. The streptomycin resistant Salmonella serovars were statistically increasing from 0.35(95% CI: 0.12–0.58) in 2003 to 0.77(95% CI: 0.64–0.89) in 2018. The level of multidrug-resistant (MDR) Salmonella serovars was 50.1% in the meta-analysis. Conclusion We found a high level of streptomycin resistance, including multidrug, Salmonella serovars among human, animals, and animal products. This resistance was significantly increasing in the last three decades (1985–2018). The resistance to streptomycin among Salmonella serovars isolated from animals was higher than humans. This mandates the continuous monitoring of streptomycin use and practicing one health approach to preventing further development of resistance in Ethiopia. Registration We conducted a systematic review and meta-analysis after registration of the protocol in PROSPERO (CRD42019135116) following the MOOSE (Meta-Analysis of Observational Studies in Epidemiology).

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“…The study showed that the organism is widely prevalent and resistant to most antibiotics. 25 Studies from Ethiopia has shown that the resistance profile is worsening even in domestic animals like dogs. In a study which looked at the presence of Salmonella in digs, it was found that 11.7% were positive for Salmonella.…”

Section: Antimicrobial Resistance Patterns In Animal Health Sector Inmentioning

confidence: 99%

“…Significantly, resistance to three or more antimicrobials was detected in 45% of the isolates. 25 Misuse of antimicrobial agents and non-adherence to standard recommendations on the withdrawal period is a problem across the continent. In a study done in Kenya, it was found that informally marketed cow's milk also had significant presence of antibiotic residues.…”

Section: Antimicrobial Resistance Patterns In Animal Health Sector Inmentioning

confidence: 99%

Building knowledge and evidence base on antimicrobial resistance in Africa, through ‘One Health’ based surveillance

Mathew

Jaguga²,

Mpundu³

et al. 2020

Clinical Epidemiology and Global Health

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Antimicrobial Resistance is threatening to upset much of the progress that developing countries have made in the healthcare domain over the last few decades. Though there are issues with the projected morbidity and mortality figures, there is a general agreement that the data collection processes need to be strengthened, especially in the context of developing countries of Asia, Africa and Latin America. The high burden of disease associated with communicable diseases in Africa, increases the overall antibiotic use and weakens the healthcare system of the continent. Even though the scale of antibiotic use may be lower than in some other regional contexts, the high burden of infectious disease makes antimicrobial resistance a priority in the continental context. In human health sector, antibiotic resistance is becoming a problem in community acquired infections as well as healthcare associated infections. This situation is fuelled by the rampant misuse of antibiotics across the African countries; and the surveillance efforts have been quite weak in this regard. Antibiotic use is increasing in food animal production too, as the continent is moving towards various intensification methods to improve productivity. Therefore the surveillance of antimicrobial resistance patterns in animal health and food animal production, has a lot of significance in understanding the potential threats to human health and food security. But for any surveillance system to be effective, especially in the context of AMR, it needs to be truly 'One Health' in its approach. The division between animal health and human health is not scientific, but cultural in its character. This has to be broken down to create a proper 'One Health' surveillance system with data integration possible at different levels.

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Prevalence and drug susceptibility pattern of Salmonella isolates from apparently healthy slaughter cattle and personnel working at the Jimma municipal abattoir, south-West Ethiopia

Cited by 20 publications

References 17 publications

Prevalence and Serotype Diversity of Salmonella in Apparently Healthy Cattle: Systematic Review and Meta-Analysis of Published Studies, 2000–2017

Prevalence and Serotype Diversity of Salmonella in Apparently Healthy Cattle: Systematic Review and Meta-Analysis of Published Studies, 2000–2017

Epidemiology of streptomycin resistant Salmonella from humans and animals in Ethiopia: A systematic review and meta-analysis

Building knowledge and evidence base on antimicrobial resistance in Africa, through ‘One Health’ based surveillance

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