Prevalence and Microbial Etiology of Surgical Site Infections Following Major Abdominal Gynecologic Surgeries in a Tertiary Care Center

T.L, Dr Sujatha.

doi:10.18535/jmscr/v5i1.105

jmscr

2017

DOI: 10.18535/jmscr/v5i1.105

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Prevalence and Microbial Etiology of Surgical Site Infections Following Major Abdominal Gynecologic Surgeries in a Tertiary Care Center

Dr Sujatha. T.L¹

Abstract: Background and Objective-Surgical site infections (SSI) are one of the common healthcare associated infections and account for approximately

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Cited by 3 publications

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Bacteriological profile of surgical site infections and their antimicrobial susceptibility pattern at a tertiary care hospital, Western Gujarat

Mehta,

Patel,

Shingala

2024

IJMMTD

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Surgical site infection (SSI) is a frequently occurring repercussion of surgery. It results in mortality and morbidity post-surgery. The present study aims to isolate the organisms causing SSI and determine the antimicrobial susceptibility patterns of the isolates.A total of 250 patient samples were included in the study, their demographic details obtained and processed as per Standard Microbiological Protocols. Antibiotic susceptibity of the positive cultures was performed using Modified Kirby-Bauer disc diffusion method. Out of the 250 samples, 102 (40.8%) samples showed positive culture growth. Positivity rates were higher in male patients (43.88%). The most prevalent Gram-negative isolate was (23.53 %), followed by (20.59%) and others. The only Gram-positive isolate was (21.57%). Most of the Gram-negative isolates were sensitive to imipenem, meropenem, ertapenem, ceftazidime-avibactam and aztreonam. Most of the gram-positive isolates were sensitive to linezolid and levofloxacin. The current analysis found that was the most often related bacteria to SSI, followed by , , and other infections. Periodic analysis of the causative organisms and their antimicrobial susceptibility pattern is necessary to confine the burden of SSI.

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Bacteriological profile of surgical site infections and their antimicrobial susceptibility pattern at a tertiary care hospital, Western Gujarat

Mehta,

Patel,

Shingala

2024

IJMMTD

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An economic model to assess the value of triclosan-coated sutures in reducing the risk of surgical site infection in obstetrics and gynecological surgeries in India

Mahajan¹,

Pillai²,

Chopra³

et al. 2020

IJOGR

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The present study demonstrates the efficacy and economic outcome of triclosan-coated sutures (TCS) Vs conventional non-antimicrobial-coated sutures (NCS) for surgical site infections (SSIs) in obstetrics and gynecology (Ob/Gyn) in India. : A systematic literature search of available evidence for both SSI incidences and TCS efficacy data in India from 1998-2018 and 2000-2018, respectively, were gathered. We collected cost data from a private and public hospital, respectively for both Laparoscopic hysterectomy (L-hysterectomy) and Cesarean-section (C-section). Cost-effectiveness of TCS in comparison to the conventional NCS was calculated using a decision-tree deterministic model. We performed one-way sensitivity analysis to compare TCS with NCS. We found a base cost -saving for C-section at private hospital, INR 5513 and public hospital INR 791 whereas for L-hysterectomy it was INR 4924 at private hospital and INR 999 at public hospital. For C-section, at private hospital, the cost-saving for SSIs per 100 surgeries at SSI incidence rates (3.77%, 7.94%, and 24.2% at low efficacy (41%) (INR 2,05,508, INR 4,41,668, and INR 13,62,526, ) and high efficacy (61%) were (INR 3,09,657, INR 6,61,018, and INR 20,31,075). For L-hysterectomy, at private hospital, the cost- saving for SSIs per 100 surgeries for SSI incidence rates (2.28%, 6.51%, and 11.7%) at low efficacy (41%) were (INR 1,32,902; INR 3,94,313; and INR 7,15,052, and high efficacy (61%) were (INR 2,01,635; INR 5,90,564; and INR 10,67,760). Decision tree modeling showed that the use of TCS resulted in cost savings for Ob/Gyn surgeries in India.

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A Study of Bacteriological Aetiological Agents in Post Operative Abdominal Wound Infections in a Tertiary Care Hospital

Jairam¹,

A²,

Rajahamsan³

et al. 2022

Global Journal for Research Analysis

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Background and Objectives: Surgical Site Infection (SSI) continues to be a major healthcareassociated infection. Primary objective: To isolate, identify and study the aerobic bacteriological spectrum of Abdominal Surgical Site Infection. Secondary objective: 1) To study the antibiotic sensitivity pattern. 2) To detect multidrug resistant strains in abdominal Surgical Site Infection. Materials and Methods: A total of 139 patients with post operative wound infections were included in this study during the course of one year from 1/10/16 to 30/09/2017. The study group included patients who underwent surgical procedure in a tertiary care hospital and developed Surgical Site Infection while in Hospital or after discharge within 30 days post surgery. These patients were followed up closely from the period of developing SSI to the time of discharge and during follow up in the hospital. Specimens such as double swabs for open surgical wounds and aspirates for localized infections were collected. Double swabs were inoculated into the following media: 5% Sheep Blood agar (SBA), MacConkey agar (MA), Salt agar (SA) and Glucose broth. Needle aspirates were also inoculated into Chocolate Agar (CA) in addition to the above media. The organisms were identied by conventional biochemical reactions and antibiotic sensitivity was done according to the CLSI guidelines 2017. Results: Out of the 139 cases in the study, the incidence of SSI's following abdominal surgeries were 41.7 %. The commonest age group for developing SSI was spread equally in the age groups between 51 – 60 and 61 – 70 years (20.14% each). Of the risk factors, Diabetes mellitus (40.28%) were associated with SSI's in 56 patients. Maximum number of cases were after Staging Laparotomies / Tumor excision for GIT Carcinoma- 48 (35.25%). 13.66 % cases were after Appendicectomy; LSCS - 12.23 %, Laparotomy- Peritonitis 10.79 %, Laparotomy- Intestinal obstruction 3.59 %, Hernioraphy 9.35 %, Tubectomy 3.59 %, TAH 7.19 %, Laparotomy -Abdominal injury 0.71 % and others 4.31 %. There were 58 (41.7%) of cases with microbial isolates and 81 (58.3%) cases were sterile. S.aureus was the predominant organism in Abdominal Surgical Site Infection 20 (34.48%), followed by E.coli and Klebsiella pneumoniae 15 (25.85%) each. Out of 15 Klebsiella pneumoniae 53.33 % were ESBL producers and 33.33 % were MBL producers. Where as in 15 E.coli isolates, 80 % were ESBL producers and 6.67 % MBL producers. Discussion: Surgical Site Infection (SSI) are the most common Health care associated infection in low and middle income countries. Surgical Site Infection was found to be higher in patients above 50 years of age which can be due to multiple factors like a low healing rate, malnutrition, mal-absorption, increased catabolic processes and low immunity. Diabetes mellitus is a major risk factor associated with Surgical Site Infections. Patients requiring prolonged hospitalization were more prone to Surgical Site Infections. Enterococcus which is a member of the normal ora of the Gastrointestinal and Genitourinary tract in humans is an emerging pathogen in abdominal Surgical Site Infections. Interpretation and Conclusion: The prevalence of multidrug resistant organisms is to be considered as a warning sign for the emerging spread of antibiotic resistance and the need for urgent implementation of strict antibiotic policy and infection control measures. Identication of SSI's involves interpretation of clinical and laboratory ndings, and it is crucial that a surveillance programme uses denitions that are consistent and standardized; otherwise inaccurate or uninterpretable SSI rates will be computed and reported.

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Prevalence and Microbial Etiology of Surgical Site Infections Following Major Abdominal Gynecologic Surgeries in a Tertiary Care Center

Abstract: Background and Objective-Surgical site infections (SSI) are one of the common healthcare associated infections and account for approximately

Cited by 3 publications

References 2 publications

Bacteriological profile of surgical site infections and their antimicrobial susceptibility pattern at a tertiary care hospital, Western Gujarat

Bacteriological profile of surgical site infections and their antimicrobial susceptibility pattern at a tertiary care hospital, Western Gujarat

An economic model to assess the value of triclosan-coated sutures in reducing the risk of surgical site infection in obstetrics and gynecological surgeries in India

A Study of Bacteriological Aetiological Agents in Post Operative Abdominal Wound Infections in a Tertiary Care Hospital

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