Prevalence and predictors of complementary and alternative medicine/non-pharmacological interventions use for menopausal symptoms within the UK Collaborative Trial of Ovarian Cancer Screening

Gentry‐Maharaj, Aleksandra; Karpinskyj, Chloe; Glazer, Clara Helene; Burnell, Matthew; Bailey, Kate; Apostolidou, Sophia; Ryan, Andy; Lanceley, Anne; Fraser, Lindsay; Jacobs, Ian; Hunter, Myra; Menon, Usha

doi:10.1080/13697137.2017.1301919

Cited by 69 publications

(11 citation statements)

References 44 publications

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“…However, drug utilization research on MHT has not kept pace with these findings. Most of the existing studies on MHT utilization do typically not report results stratified by hormonal agent and route of administration and are mainly cross‐sectional in design, that is, information on duration of use or temporal trends is rarely available 13‐17 . Furthermore, use of MHT is expected to differ by age but stratification by age has often not been a focus in existing studies, partly due to sample size.…”

Section: Introductionmentioning

confidence: 99%

Prescribing of menopausal hormone therapy in Germany: Current status and changes between 2004 and 2016

Heinig

Braitmaier

Haug

2021

Pharmacoepidemiology and Drug

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Background Prescribing of menopausal hormone therapy (MHT) declined drastically after publication of the Women's Health Initiative's (WHI) findings in 2002, but studies on longer‐term trends and details of use are scarce. Methods We used the German Pharmacoepidemiological Research Database (GePaRD) containing health insurance claims data from ~25 million persons. Using data from 2004–2016, we conducted cross‐sectional analyses to determine the prevalence of MHT use overall and by type and route of administration in women aged 45–75. In longitudinal analyses, we assessed MHT use over 5 years and compared the patterns between different time periods. Results From 2004 to 2016, prevalence of systemic MHT prescriptions decreased by >60% in women aged 55–65 and by >50% in women aged 50 and 70 years old. Prevalence declined for most types and routes of administration at all ages (−16% to −79%) with some exceptions, for example, local MHT (vaginal estrogen). Among 50‐year‐old women in 2012, 6% were already prescribed systemic MHT at age 49 and of the remaining women, 16% were newly prescribed systemic MHT before age 55. At all ages, the cumulative dose of systemic MHT prescribed over 5 years was lower in the period 2012–2016 compared to 2005–2009 (−6% to −46%). Conclusions For most types of MHT and all age groups, prevalence declined considerably between 2004 and 2016 in Germany. The cumulative dose per MHT user also decreased, suggesting a trend towards a shorter duration of use.

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Section: Introductionmentioning

confidence: 99%

Prescribing of menopausal hormone therapy in Germany: Current status and changes between 2004 and 2016

Heinig

Braitmaier

Haug

2021

Pharmacoepidemiology and Drug

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“…[ 22 ] One out of every 4 women uses complementary and nonpharmacological treatments to relieve menopausal symptoms. [ 23 ] The World Health Organization has suggested complementary and alternative medicine as ways to improve menopausal symptoms and increase the sense of well-being in women. [ 24 ] Complementary medicines used in menopause include mind-body practices (such as hypnosis, meditation, aromatherapy), natural products (such as herbs, vitamins, dietary supplements, and minerals), traditional Chinese medicine, reflexology, acupuncture, acupressure, and homeopathy.…”

Section: Introductionmentioning

confidence: 99%

Investigation of the role of herbal medicine, acupressure, and acupuncture in the menopausal symptoms: An evidence-based systematic review study

Ebrahimi

Tayebi

Ahmadinezhad

et al. 2020

J Family Med Prim Care

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Background: Menopause is an important physiological phenomenon in women's lives. Women's concern about taking the hormone treatment to ease menopausal symptoms is increasing. Over the past decade, the use of complementary and alternative medicine for the treatment of menopausal problems instead of hormone therapy has increased. Objective: This study aimed to investigate the role of herbal medicine, acupressure, and acupuncture in the menopausal symptoms. Methods: Data source: related articles were searched from internal scientific databases and external databases of “Web of Scopus, Cochrane, PubMed, Science Direct, Ovid, and Google scholar.” Study Eligibility Criteria: The keywords such as menopause, menopausal symptoms, complementary menopausal medicine, acupuncture in menopause, herbal medicine in menopause, and acupuncture in menopause were searched in the studies from 1987 to 2019. Exclusion criteria were inadequate information in the study, lack of access to full-text articles, animal studies, and reports. At the end of the search, 145 articles out of a total of 400 articles were reviewed. Results: In various studies, different herbs such as licorice, valerian, soy, sage, ginseng, etc., were used to improve menopausal symptoms. In addition, acupuncture and acupressure were used to reduce menopausal symptoms. Conclusion: The efficacy and use of complementary and alternative medicine, along with other classical medicine care, can be a new model for improving menopausal symptoms in women. It is recommended that further clinical and review studies be conducted to develop complementary and alternative medicine.

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“…Vasomotor symptoms respond well to HT, however, due to increased fears around its use 23 , the number of women using HT and doctors prescribing it has declined. This has led to women seeking out alternatives to HT 24 , of which soy is one.…”

Section: Introductionmentioning

confidence: 99%

The effect of a randomized 12-week soy drink intervention on everyday mood in postmenopausal women

et al. 2019

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Objective: Dietary soy may improve menopausal symptoms, and subsequently mediate mood. This novel study examines various does of dietary soy drink on everyday mood stability and variability in postmenopausal women. Methods: Community dwelling women (n=101), within 7 years post menopause consumed daily either a low (10mg, n=35), medium (35mg, n=37) or high (60mg, n=29) dose of isoflavones, for twelve weeks. Menopausal symptoms and repeated measures of everyday Mood (Positive (PA) and Negative (NA) affect) (assessed at four time points per day for four consecutive days, using PANAS) were completed at baseline and follow up. Results: The dietary soy intervention had no effect on everyday mood stability (for PA (F(2,70) = .95, p = .390) and NA (F(2,70) = 0.72, p = .489) or variability (for PA (F(2,70) = .21, p = .807) and for NA (F(2,70) = .15, p=.864) or on menopausal symptoms (for vasomotor (F (2,89) = 2.83, p = .064), psychological (F (2,88) = 0.63, p = .535), somatic (F (2,89) = 0.32, p =.729) and total menopausal symptoms (F (2,86) = 0.79, p = .458)). There were between group differences with the medium dose reporting higher PA (low, mean: 24.2, SD: 6 and medium, mean: 29.7, SD: 6) and the low dose reporting higher NA (P = 0. 048) (Low, mean: 11.6, SD: 2 and high, mean: 10.6, SD: 1) in mood scores. Psychological (baseline M = 18 and follow up M = 16.5) and vasomotor (baseline M = 4.2 and follow up M = 3.6) scores declined from baseline to follow up for the overall sample. Conclusions: Soy isoflavones had no effect on mood at any of the doses tested. Future research should focus on the menopausal transition from peri to post menopause as there may be a window of vulnerability, with fluctuating hormones and increased symptoms which may affect mood.

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Prevalence and predictors of complementary and alternative medicine/non-pharmacological interventions use for menopausal symptoms within the UK Collaborative Trial of Ovarian Cancer Screening

Cited by 69 publications

References 44 publications

Prescribing of menopausal hormone therapy in Germany: Current status and changes between 2004 and 2016

Prescribing of menopausal hormone therapy in Germany: Current status and changes between 2004 and 2016

Investigation of the role of herbal medicine, acupressure, and acupuncture in the menopausal symptoms: An evidence-based systematic review study

The effect of a randomized 12-week soy drink intervention on everyday mood in postmenopausal women

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