Prevalence characteristics of human papillomavirus (HPV) infection among women receiving physical examinations in the Shangcheng District, Hangzhou city, China

Wang, Lu; Yu, Chunfeng; Ni, Xiaoling; Wang, Fang; Wen, Caihe; Jin, Mei; Chen, Juanjuan; Zhang, Kunming; Wang, Jiahao

doi:10.1038/s41598-021-96131-y

Cited by 7 publications

(6 citation statements)

References 32 publications

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“…Meanwhile, the regions of Western and Middle China have similar HPV rates of 13.5% (Shannxi) [ 29 ], 12.6–15.29% (Sichuan) [ 30 , 31 ], 12.09% (Henan) [ 32 ], 13.56% (Jiangxi) [ 33 ], and 13.88% (Hunan) [ 34 ]. In contrast, HPV prevalence in Eastern China is reported to vary greatly from 10.6% (Jiangsu) [ 17 ] to 22.41% (Zhejiang) [ 35 ]. In Zhejiang [ 36 ], data from routine physical examinations performed indicate the prevalence of HPV is 13.6%.…”

Section: Discussionmentioning

confidence: 99%

“…For HPV detection and genotyping, two commercial HPV Genotyping Kits (Shanghai ZJ Bio-Tech Co., Ltd.) were used to detect fifteen high risk (HR)-HPV types (16,18,31,33,35,39,45,51,52,56,58,59, 66, 68, and 82) and a combination of two low-risk (LR)-HPV types (6/11) with use of TaqMan real-time fluorescent quantitative polymerase chain reaction (PCR) using a Slan-96P Real-time PCR System assay (Hongshi Medical Technology Co., Ltd., Shanghai, China). Samples were reported to be HPV positive if any of the 17 HPV DNA types were detected.…”

Section: Sample Collection Hpv Detection and Genotypingmentioning

confidence: 99%

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Prevalence and genotype distribution of human papillomavirus infections in Beijing, China between 2016 and 2020

Zhang

Guo

et al. 2023

Virol J

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Background Certain types of human papillomavirus (HPV) induce long-lasting infections that cause cervical cancer. This study evaluated the prevalence of HPV infections and the distribution of their genotypes among clinic patients and healthy women in Beijing, China. Methods Cervical specimens were collected from 12,100 patients and 1176 subjects who underwent physical examinations at Dongzhimen Hospital, Beijing University of Chinese Medicine, between March 2016 and September 2020. HPV genotyping was performed using commercial kits designed to detect 15 high-risk and 2 low-risk HPV genotypes. Results There was a higher overall prevalence of HPV among the clinic patients (21.0%) than among the healthy women (11.9%). The most common HPV genotypes among the patients were: HPV-52 (5.4%), HPV-16 (3.4%), HPV-58 (3.2%), HPV-51 (2.6%), HPV-39 (2.0%), HPV-56 (2.0%), and HPV-66 (2.0%). Among the healthy women: HPV-52 (3.0%), HPV-51 (1.8%), HPV-58 (1.6%), HPV-66 (1.5%), HPV-16 (1.2%), HPV-56 (1.2%), and HPV-18 (1.1%). Multiple HPVs were detected in 29.1% of the gynecological outpatients and in 23.6% of the women receiving physical examinations. The most common pairs of HPV types detected were HPV-52 and HPV-16 in the clinic patients, and HPV-52 and HPV-56 in the healthy women. Age-specific HPV positivity and peak prevalence were observed among the individuals in both groups for women aged less than 25 years and those between 61 and 65 years of age. Conclusions Our results provide current estimates of HPV prevalence and genotypes in the Beijing region. The epidemiological characteristics observed also provide a reference for the development of cervical cancer screening strategies and selection of HPV vaccine antigen targets for this region. A comparison of these HPV prevalence data with those from other regions suggests that regional vaccines may be an important direction for future research.

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Section: Discussionmentioning

confidence: 99%

Section: Sample Collection Hpv Detection and Genotypingmentioning

confidence: 99%

Prevalence and genotype distribution of human papillomavirus infections in Beijing, China between 2016 and 2020

Zhang

Guo

et al. 2023

Virol J

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“…We evaluated HR-HPV cases in three groups of type 16, type 18, and other types based on the data. Wang et al reported that prevalence rates of type 16 and 18 were 3.95%, and 3.27% in Chinese women, respectively (Wang et al 2021). In a study conducted with Mexican women, the most common types were type 16 (43%) and 18 (42%) (López Rivera et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Genotype Distribution and Prevalence of High-Risk Human Papillomavirus Infection among Women in Samsun Province of Turkey

Taşkın

Nursal²,

Oruç³

et al. 2022

Asian Pac J Cancer Prev

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Cervical cancer (CC), the fourth most frequently diagnosed cancer, is the fourth major death cause of women, showing an estimated 342,000 deaths and 604,000 new cases worldwide in 2020 (Sung et al.,2021). CC is increasing in number every year, and the patient population is getting younger. Thus, CC endangers women's life and health as a significant disease (Olusola et al., 2019). An essential step in human development and reproduction is to focus on women's health. We still focus on prevention at present due to CC. Hence, the factors affecting the development and occurrence of cervical cancer should be considered for our research and discussion.Human papillomavirus (HPV), the most prevalent sexually transmitted infection globally, negatively impacts personal social life (Chesson et al., 2014). HPV belongs to

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“…However, China has implemented rigorous epidemic prevention measures over the course of 3 years, surpassing those of most other countries worldwide. 39 The investigation of the correlation between HPV infection and long-term control measures to 22.41%, [40][41][42] with a higher prevalence observed among clinicbased patients than in general population, ranging from 17.92% to 50.64%. 43,44 In the current investigation, the aggregate HPV infection rate among outpatients admitted at PUMCH during the prepandemic period was found to be 33.54%.…”

Section: Discussionmentioning

confidence: 99%

“…High-risk HPV (HR-HPV) types, such as HPV16, 18,31,33,35,39,45,51,52,56,58,59, and 68, are known to cause cervical intraepithelial neoplasia, cervical cancer, and other malignant lesions. 6 Conversely, low-risk HPV (LR-HPV) types, including HPV6, 11,42,43,44,54,61,70,72, and 81, are associated with benign lesions such as genital warts. 7,8 HPV16 and 18 are causally linked to approximately 70% of cervical cancer cases, whereas HPV6 and 11 are responsible for 90% of condyloma acuminatum cases.…”

Section: Introductionmentioning

confidence: 99%

The impact of the COVID‐19 pandemic on the prevalence and genotype distribution of HPV infection in Beijing, China

Yi,

Li,

Zhang

et al. 2023

Journal of Medical Virology

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Human papillomavirus (HPV) is one of the most common sexually transmitted infections nationwide. The COVID‐19 pandemic has greatly influenced on the HPV prevention project. The objective of this study was to examine the influence of the pandemic on HPV prevalence and genotype distribution in Beijing, China. A total of 44 401 genital swabs were obtained from outpatients at Peking Union Medical College Hospital during two distinct periods: the prepandemic stage from January 2017 to December 2019 and the pandemic stage from January 2020 to December 2022. During the prepandemic and pandemic stages, a total of 33 531 and 10 870 swabs were respectively collected. Fifteen high‐risk HPV (HR‐HPV) DNA type and a combination of two low‐risk (LR‐HPV) types (6/11) of genital swabs were detected to compare the HPV infection rates and genotype distributions in two stages. The results showed that the pandemic period witnessed a decrease in the overall HPV infection rate from 33.43% (11 245/33 531) to 29.43% (5527/18 780) compared to the prepandemic. There were statistically significant differences in infection rates between females and males (p < 0.05). Single infection was the predominant type while multiple infection was more prevalent in males than females in both prepandemic and pandemic periods. HR‐HPV infection constituted the majority of infections and cannot be disregarded. The distribution of HR‐HPV genotypes exhibited little variation before and after the outbreak, but there were some differences between females and males. HPV 16, 52, 58, 56, and 66 were the most commonly detected genotypes in females, whereas HPV 16, 52, 51, 58, and 18 were frequently detected in males. Additionally, HPV 6/11 exhibited a higher prevalence in males than in females. Notably, the age group of 31−40 years old exhibited the highest prevalence of HPV and the lowest infection rate was detected among individuals aged ≤20 years (p < 0.05), which remained relatively consistent before and during the pandemic. These findings underscore the importance of monitoring the trend of HPV epidemic and offer valuable insights for the prevention, treatment, and scientific investigation of HPV in the post‐COVID‐19 era.

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Prevalence characteristics of human papillomavirus (HPV) infection among women receiving physical examinations in the Shangcheng District, Hangzhou city, China

Cited by 7 publications

References 32 publications

Prevalence and genotype distribution of human papillomavirus infections in Beijing, China between 2016 and 2020

Prevalence and genotype distribution of human papillomavirus infections in Beijing, China between 2016 and 2020

Genotype Distribution and Prevalence of High-Risk Human Papillomavirus Infection among Women in Samsun Province of Turkey

The impact of the COVID‐19 pandemic on the prevalence and genotype distribution of HPV infection in Beijing, China

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