Prevalence of dyslipidemia in adolescents: Comparison between definitions

Tomeleri, Crisieli M.; Ronque, Ênio Ricardo Vaz; Silva, Danilo; Júnior, Crivaldo Gomes Cardoso; Fernandes, Rômulo Araújo; Teixeira, Denílson C.; Barbosa, Domingos Sávio; Venturini, Danielle; Okino, Alessandra Miyuki; Oliveira, João; Cyrino, Edílson Serpeloni

doi:10.1016/j.repc.2014.08.020

Cited by 20 publications

(15 citation statements)

References 26 publications

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“…Definition of dyslipidaemia is unclear due to the indiscriminate use of different diagnostic criteria, which may result in inaccurate interpretations, and lead to marked variations in the prevalence of dyslipidaemia reported in different studies [8]. There are few studies regarding the prevalence of dyslipidaemia in the ME [9e12].…”

Section: Introductionmentioning

confidence: 99%

Dyslipidaemia in the Middle East: Current status and a call for action

Al-Rasadi

Almahmeed²,

AlHabib

et al. 2016

Atherosclerosis

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The increase in the cardiovascular disease (CVD)-associated mortality rate in the Middle East (ME) is among the highest in the world. The aim of this article is to review the current prevalence of dyslipidaemia and known gaps in its management in the ME region, and to propose initiatives to address the burden of dyslipidaemia. Published literature on the epidemiology of dyslipidaemia in the ME region was presented and discussed at an expert meeting that provided the basis of this review article. The high prevalence of metabolic syndrome, diabetes, familial hypercholesterolaemia (FH) and consanguineous marriages, in the ME region, results in a pattern of dyslipidaemia (low high-density lipoprotein cholesterol and high triglycerides) that is different from many other regions of the world. Early prevention and control of dyslipidaemia is of paramount importance to reduce the risk of developing CVD. Education of the public and healthcare professionals and developing preventive programs, FH registries and regional guidelines on dyslipidaemia are the keys to dyslipidaemia management in the ME region.

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Section: Introductionmentioning

confidence: 99%

Dyslipidaemia in the Middle East: Current status and a call for action

Al-Rasadi

Almahmeed²,

AlHabib

et al. 2016

Atherosclerosis

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“…Dyslipidemia broadly describes abnormalities associated with serum lipid metabolism. Its clinical consequences are elevated levels of total cholesterol, triglycerides, and LDL cholesterol, and decreased high-density lipoprotein (HDL) cholesterol levels [ 12 ]. Dyslipidemia is one of the risk factors of CVD and a main component of metabolic syndrome.…”

Section: Introductionmentioning

confidence: 99%

Low Urinary Iodine Concentrations Associated with Dyslipidemia in US Adults

2016

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Iodine is an essential component of the thyroid hormone which plays crucial roles in healthy thyroid function and lipid metabolism. However, the association between iodine status and dyslipidemia has not been well established at a population level. We aimed to test the hypothesis that the odds of dyslipidemia including elevated total cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol and apolipoprotein B, and lowered high-density lipoprotein (HDL) cholesterol and HDL/LDL ratio are associated with urinary iodine concentration (UIC) in a population perspective. Data of 2495 US adults (≥20 years) in the National Health and Nutrition Examination Survey 2007–2012 were used in this study. Two subgroups (i.e., UIC below vs. above the 10th percentile) were compared of dyslipidemia as defined based on NCEP ATP III guidelines. The differences between the groups were tested statistically by chi-square test, simple linear regressions, and multiple logistic regressions. Serum lipid concentrations differed significantly between two iodine status groups when sociodemographic and lifestyle covariates were controlled (all, p < 0.05). Those with the lowest decile of UIC were more likely to be at risk for elevated total cholesterol (>200 mg/dL) (adjusted odds ratio (AOR) = 1.51, 95% confidence interval (CI): 1.03–2.23) and elevated LDL cholesterol (>130 mg/dL) (AOR = 1.58, 95% CI: 1.11–2.23) and lowered HDL/LDL ratio (<0.4) (AOR = 1.66, 95% CI: 1.18–2.33), compared to those with UIC above the 10th percentile. In US adults, low UIC was associated with increased odds for dyslipidemia. Findings of the present cross-sectional study with spot urine samples highlight the significant association between UIC and serum lipids at population level, but do not substantiate a causal relationship. Further investigations are warranted to elucidate the causal relationship among iodine intakes, iodine status, and serum lipid profiles.

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“…First, the independence between both is justi ed because as mentioned above, physical activity seems particularly related to health care costs attributed to medication, while LDL-C values were related to health care costs attributed to primary and secondary care (r = 0.291; p-value = 0.009). In fact, dyslipidemia is a health outcome with growing prevalence among adolescents (reaching 61% depending on the cut point adopted) [37] and, naturally, leading to a higher number of medical consultations in order to treat it. Moreover, even assuming that alterations in LDL-C concentration are strongly affected by obesity, this is not mandatory, because dyslipidemia also occurs in children and adolescents with normal weight but with poor diet habits [38].…”

Section: Discussionmentioning

confidence: 99%

Moderating Effect of Vigorous Physical Activity on Health Care Costs among Adolescents: ABCD Growth Study

Chagas¹,

Fernandes²,

Araújo³

et al. 2021

Preprint

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Background: The relationship between physical activity and health care costs among adolescents is not yet clear in the literature.Objective: To analyze the relationship between physical activity and annual health care costs among adolescents.Methods: The present sample was composed of 85 adolescents of both sexes with ages ranging from 11 to 18 years (mean age 15.6±2.1). Health care costs were self-reported every month for 12 months, and information on health care values was verified at local pharmacies, private health care plans, and the National Health Service. The time spent in different physical activity intensities was objectively measured by accelerometers. Confounding variables were: sex, age, somatic maturation, body fatness, blood pressure, and components of dyslipidemia and insulin resistance. Multivariate models were generated using generalized linear models with gamma distribution and a log-link function.Results: The overall annual health care cost was US$ 733.60/ R$ 2,342.38 (medication: US$ 400.46 / R$ 1,278.66; primary and secondary care: US$ 333.14 / R$ 1,063.70). The time spent in vigorous physical activity (minutes/day) was negatively related to health care costs (r= -0.342 [95% CI: -0.537, - 0.139]; β= -0.06 cents (95% CI: -0.089, -0.031).Conclusion: Vigorous physical activity seems to be associated with lower health care costs among adolescents.

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Prevalence of dyslipidemia in adolescents: Comparison between definitions

Abstract: Although a high prevalence of dyslipidemia was observed in this study regardless of the diagnostic criteria used, the wide variation in rates highlights the need to establish a single definition with appropriate discriminatory power for adolescents.

Cited by 20 publications

References 26 publications

Dyslipidaemia in the Middle East: Current status and a call for action

Dyslipidaemia in the Middle East: Current status and a call for action

Low Urinary Iodine Concentrations Associated with Dyslipidemia in US Adults

Moderating Effect of Vigorous Physical Activity on Health Care Costs among Adolescents: ABCD Growth Study

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