Prevalence of extended-spectrum beta-lactamase producing bacteria from animal origin: A systematic review and meta-analysis report from India

Kuralayanapalya, Suresh P.; Patil, S. S.; Hamsapriya, Sudhakar; Shinduja, Rajamani; Roy, Parimal; Amachawadi, Raghavendra G.

doi:10.1371/journal.pone.0221771

Cited by 32 publications

(22 citation statements)

References 30 publications

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“…ESBL and Carbapenemase production seems to be the primary cause of MDR in gut bacteria. Similarly, other studies have observed a high likelihood of ESBL carriage to contribute to MDR among gut bacteria 57,58 . Surveillance of ESBL and carbapenemase production could be one major and useful step in the control of the spread of MDR bacteria in both humans and animals.…”

Section: Discussionmentioning

confidence: 61%

Antimicrobial resistance at the human–animal interface in the Pastoralist Communities of Kasese District, South Western Uganda

Iramiot

Kajumbula

Bazira

et al. 2020

Sci Rep

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Intensive usage of antimicrobials in the management of animal diseases leads to selection for resistance among microorganisms. This study aimed to assess antimicrobial use and to describe factors associated with the transmission of antimicrobial resistance between humans and animals in pastoralist communities of Kasese district. A mixed-methods approach was employed in this study. Rectal swabs were collected from the participants and cattle and transported in Carry–Blaire transport medium to the laboratory within 24 h of collection for culture and sensitivity to confirm carriage of multi-drug resistant bacteria. In-depth interviews were conducted among veterinary officers, veterinary drug vendors, human health facility in-charges in both public and private health facilities, and operators of human pharmacies and drug shops. Carriage of multi-drug resistant bacteria among humans was 88 (93%) and 76(80%) among cattle. Consumption of lakeshore water and carriage of multi-drug resistant bacteria in cattle were associated with carriage of multi-drug resistant bacteria in the human population. The prevalence of multi-drug resistance among organisms Isolated from both humans and animals was high. There is a high likelihood of transmission of multi-drug resistance between humans and animals.

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Section: Discussionmentioning

confidence: 61%

Antimicrobial resistance at the human–animal interface in the Pastoralist Communities of Kasese District, South Western Uganda

Iramiot

Kajumbula

Bazira

et al. 2020

Sci Rep

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“…In addition, K. pneumoniae has been considered to be an important food-borne pathogen found in many food types [ 4 , 5 , 6 ]. Recently, MDR K. pneumoniae strains have recently spread and increased so that they have emerged as a cause of recalcitrant infections worldwide [ 49 , 50 , 51 ]. Bacteriophage therapy is therefore an effective alternative to multiple drug-resistant pathogens [ 52 ].…”

Section: Resultsmentioning

confidence: 99%

Characterization and Full Genome Sequence of Novel KPP-5 Lytic Phage against Klebsiella pneumoniae Responsible for Recalcitrant Infection

et al. 2021

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Klebsiella pneumoniae is a hazardous opportunistic pathogen that is involved in many serious human diseases and is considered to be an important foodborne pathogen found in many food types. Multidrug resistance (MDR) K. pneumoniae strains have recently spread and increased, making bacteriophage therapy an effective alternative to multiple drug-resistant pathogens. As a consequence, this research was conducted to describe the genome and basic biological characteristics of a novel phage capable of lysing MDR K. pneumoniae isolated from food samples in Egypt. The host range revealed that KPP-5 phage had potent lytic activity and was able to infect all selected MDR K. pneumoniae strains from different sources. Electron microscopy images showed that KPP-5 lytic phage was a podovirus morphology. The one-step growth curve exhibited that KPP-5 phage had a relatively short latent period of 25 min, and the burst size was about 236 PFU/infected cells. In addition, KPP-5 phage showed high stability at different temperatures and pH levels. KPP-5 phage has a linear dsDNA genome with a length of 38,245 bp with a GC content of 50.8% and 40 predicted open reading frames (ORFs). Comparative genomics and phylogenetic analyses showed that KPP-5 is most closely associated with the Teetrevirus genus in the Autographviridae family. No tRNA genes have been identified in the KPP-5 phage genome. In addition, phage-borne virulence genes or drug resistance genes were not present, suggesting that KPP-5 could be used safely as a phage biocontrol agent.

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“…None of the studied isolates produced an ESBL, while a large number of worldwide studies reported their important rate isolation especially from food-producing animals as chicken, beef, pork, and milk [ 21 , 22 , 51 – 53 ]. The ESBL absence is a positive point since the food is essentially destined to immune-depressed patients.…”

Section: Discussionmentioning

confidence: 99%

Molecular Serotyping and Antibiotic Resistance Patterns of Escherichia coli Isolated in Hospital Catering Service in Morocco

Touimi

Bennani

Berrada

et al. 2020

International Journal of Microbiology

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Escherichia coli is related to foodborne disease and outbreaks worldwide. It mainly affects persons at high risk as newborns, infants, and individuals with impaired immune system in hospitals. Multidrug-resistant E. coli is currently spreading both in community and hospital settings. Our study aims to evaluate the presence of E. coli and the incidence of its antibiotic resistance in samples obtained from various cooked and raw foods (N = 300), food contact surfaces (N = 238), and food handlers (N = 40) in Moroccan hospital catering service. E. coli was identified using API 20E, and the antibiotic resistance patterns were obtained using the agar disk diffusion methods. However, PCR method was used for O157 and H7 typing. The samples analysis showed that 14.33%, 24.16%, and 45% of food, surfaces, and food handlers harbored E. coli, respectively, with the highest rates obtained in raw meats (34.88%) and salads (34.88%). Molecular amplification shows that 14 E. coli isolates carried the flagellar antigen H7, while there are no isolates showing amplification for O157. The high rate of resistance was noted against ampicillin (100%), amoxicillin-clavulanate acid (100%), nalidixic acid (61.62%), and cefotaxime (59.49%), and isolates obtained from food handler’s hands showed the highest rates of resistance. None of the isolates are extended-spectrum beta-lactamases producing, while 27.7% of the isolates were metallo-beta-lactams producing. This first study conducted on Moroccan hospital catering services may draw the authorities’ attention to the necessity of setting up a surveillance system to monitor the food preparation process and the safety of prepared food in healthcare settings.

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Prevalence of extended-spectrum beta-lactamase producing bacteria from animal origin: A systematic review and meta-analysis report from India

Cited by 32 publications

References 30 publications

Antimicrobial resistance at the human–animal interface in the Pastoralist Communities of Kasese District, South Western Uganda

Antimicrobial resistance at the human–animal interface in the Pastoralist Communities of Kasese District, South Western Uganda

Characterization and Full Genome Sequence of Novel KPP-5 Lytic Phage against Klebsiella pneumoniae Responsible for Recalcitrant Infection

Molecular Serotyping and Antibiotic Resistance Patterns of Escherichia coli Isolated in Hospital Catering Service in Morocco

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