Prevalence of human papillomavirus infection of 65,613 women in East China

Abstract

BackgroundThe infection with human papillomavirus (HPV) is the major cause of genital disease. This study assessed the prevalence and genotype of HPV among outpatient women and healthy women in Jiangsu, East China.MethodsA total of 65,613 women aged 16–85 years were recruited from Nanjing Kingmed Diagnostics, including 45,736 outpatients and 19,877 healthy women. The cervico-vaginal cells were collected and then HPV types were detected using the Tellgenplex™ HPV DNA Test.ResultsThe overall HPV prevalence was 17.7% for outpatients and 10.6% for healthy women. 13.7% outpatients were infected with a single HPV type and 4.0% were infected with multiple HPV types. Regarding healthy women, 8.5 and 2.1% were infected with single and multiple HPV types, respectively. The two most commonly detected HPV types were HPV 16 and 58 regardless of single- or multiple-type infection or source of the participants. HPV16 + 58 was the most commonly identified multiple genotype in outpatients, while HPV16 + 52 was frequently detected in healthy women. Highest prevalence rate was found in outpatients aged < 20 years and ≥ 60 years.ConclusionsThis study revealed the prevalence characteristics of HPV in both outpatient women and healthy women in Jiangsu province.Electronic supplementary materialThe online version of this article (10.1186/s12889-019-6487-9) contains supplementary material, which is available to authorized users.

Diagnostic screening of HPV genotypes in 555 Ecuadorian mestizo women of seven provinces, and comparison with other Latino American populations

“…Four positive cases were also observed in women older than 55 years, equivalent to 0.36% of the analyzed sample. The general prevalence of HPV in the studied population was 6.3%; this percentage is lower in comparison with other countries as Mexico that reports in healthy women only 9.1% [36], Turkey with 17.9% [37], or East China with 10.6% [38]. It is important to note that there are very few diagnostic screening studies conducted in healthy women.…”

Human Papillomavirus (HPV) Vaccine Uptake and the Willingness to Receive the HPV Vaccination among Female College Students in China: A Multicenter Study

“…One possible tactic for raising the perception of susceptibility among young people is to raise their awareness of the high degree of infectiousness of HPV in China. It is of the utmost importance to inform young college women about recent data showing the high prevalence of HPV among women in China [13,14], and most importantly that young women are the group with the highest HPV infection rate [15].…”

The prevalence and genotype distribution of human papillomaviruses among women in Taizhou, China

“…The overall prevalence of HPV (34.58%) in our study was higher than that in other regions in China, such as Shandong (28.4%), [17] Zhejiang (22.8%), [18] Shanghai (31.84%), [19] Nanhai area of Foshan (13.5%), [20] Jiangxi (22.49%), [21] and Jiangsu (15.5%). [22] The prevalence of HR-HPV (29.92%) was also higher than that in most regions in China but lower than that in Haikou (31.94%) and Shanghai (34.68%). [19] The findings reveal that Taizhou has a higher prevalence of HPV infection than other regions in China.…”

“…In the present study, the 5 most common types of HPV in Taizhou were HPV-52, HPV-16, HPV-53, HPV-58, and HPV-81, whereas HPV-18 had a relatively low prevalence, which was in agreement with that in Shandong Province [17] but was slightly different from most previous studies in other regions of China, such as Zhejiang Province, [18] Shanghai, [19] and even Jiangsu Province. [22] The reason for the inconsistencies may be that hospital population-based surveys are opportunistic screenings with a selection bias and the levels of economic development in different regions of Jiangsu Province varies greatly. On the other hand, HPV-16 plays a predominant role in all regions while other subtypes vary in different regions in China.…”