Prevalence of Microalbuminuria with Relation to Glycemic Control in Type-2 Diabetic Patients in Mymensingh

Abstract

Diabetes is one of the most common endocrine disorders characterized by hyperglycaemia. Diabetic nephropathy is a consequence of long standing diabetes. The prevalence of microalbuminuria predicts progression to diabetic nephropathy. The present study was conducted to determine the prevalence of microalbuminuria in relation to duration of diabetes, BMI, Serum Creatinine and HbA1c in an ethnic group of Type 2 diabetes mellitus residing in Mymensingh, Bangladesh. This descriptive cross-sectional study was carried out in a community based medical college hospital, located at Winnerpar, Mymensingh from July to December 2012. Fasting various blood and morning urine sample was collected for analysis of creatinine, HbA1c and microalbuminuria respectively. One hundred twenty known Type 2 diabetic patients with age 30 years and above were included in the study. Pearson correlation was applied to observe association of microalbuminuria with different parameters. Microalbuminuria had a highly significant correlation with duration of diabetes (p<0.001), serum creatinine, HbA1c (p<0.001) and BMI (p 0.001). The correlation demonstrates that with the increase in age, raised serum creatinine significantly bearing a perfect positive correlation as evident by r = 0.878, p < 0.001. The present study found an early onset of microalbuminuria in the selected community which could be due to poor glycaemic control (high HbA1c >7%) or heredity factors. Screening for microalbuminuria and HbA1c test should be done in both newly and already diagnosed Type 2 diabetic patients as an early marker of renal dysfunction and glycaemic control.
 CBMJ 2014 January: Vol. 03 No. 01 P: 29-34

Frequency of microalbuminuria and its relation to HbA1C in type 2 Diabetes mellitus patients.

“…16 The present study demonstrated that higher proportion of patient (56.7%) with microalbuminuria had poor glycemic control that is serum HbA1c > 6.5%. These findings are consistent with the other Pakistani studies by Sheikh et al and Hasan et al 17,18 These studies also reported a significant correlation of microalbuminuria with HbA1c level among type 2 diabetic patients. Moreover, Ahmed et al and Walraven et al also reported a strong correlation between the higher glycemic level and microalbuminuria.…”

Socio-demographic Characteristics and Cognitive Function in Adults with Type 2 Diabetes Mellitus

“…The finding was almost similar to the study conducted by Yaffeet al 6 , 2009 and Barzilay et al10 . In this study the mean age of onset of DM was 41.6±6.9 years with minimum age 23 and maximum 54 years which is similar to the study conducted by Hasan et al11 . Study conducted by Yaffeet al6 and Akrivos et al12 showed that the mean duration of diabetes was 10.4 ± SD 7.3 years.…”

Association between glycemic control and albuminuria among Peruvian adults with diabetes mellitus 2: a cross-sectional analytical study

“…15 In another study in a primary care center, the prevalence of albuminuria was 17.9% among diabetes patients and 10.8% among hypertension patients. 16 Poor glycemic control has been correlated with albuminuria in various studies using HbA1C, [17][18][19][20][21] while intensive glucose control reduces the risk of albuminuria. 21 However, although studies have been conducted in different ethnic groups, few studies have included any significant proportion of Hispanic patients, despite the evidence that there are ethnic variations in albuminuria prevalence among diabetic patients.…”