Prevalence of Migraine in Patients With Celiac Disease and Inflammatory Bowel Disease

Dimitrova, Alexandra; Ungaro, Ryan C.; Lebwohl, Benjamin; Lewis, Suzanne K.; Tennyson, Christina A.; Green, Mark W.; Babyatsky, Mark W.; Green, Peter H.

doi:10.1111/j.1526-4610.2012.02260.x

Cited by 123 publications

(127 citation statements)

References 41 publications

Supporting

Mentioning

114

Contrasting

Unclassified

Order By: Relevance

“…Moreover, it has been reported that the headache attacks of patients with the diagnosis of migraine and co-existing CD diminish with GFD. Dimitrova et al (26) analyzed 502 subjects: 188 with CD, 111 with infl ammatory bowel disease, 25 with gluten sensitivity, and 178 controls. In multivariate logistic regression, CD subjects had a signifi cantly higher prevalence of migraine headache compared with controls (26).…”

Section: Discussionmentioning

confidence: 99%

“…Dimitrova et al (26) analyzed 502 subjects: 188 with CD, 111 with infl ammatory bowel disease, 25 with gluten sensitivity, and 178 controls. In multivariate logistic regression, CD subjects had a signifi cantly higher prevalence of migraine headache compared with controls (26). Interestingly, no correlation between years on gluten-free diet and migraine severity was determined in that study.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Celiac Disease and Associated Neurological Conditions

IŞIKAY¹,

HIZLI²

2015

Turkish J Pediatr Dis

View full text Add to dashboard Cite

Objective: Celiac disease has been associated with many neurological disorders. In this report, we discuss 16 patients with both celiac disease and neurological symptoms and evaluate the overall neurological features of celiac disease in the light of the current literature to emphasize the neurological aspects of celiac disease. Material and Methods:The medical records of all patients diagnosed with celiac disease between 2010 and 2012 were reviewed.Results: Nine of these 16 cases were female while seven were male with a mean age of 10.34±3.76 years (5-16 years). The reported neurological problems of these 16 children with celiac disease were epilepsy (n=10), mental retardation (n=9), ataxia (n=3), neuropathy (n=1), headache (n=2), febrile seizure (n=1), and neurofi bromatosis type 1 (plus headache) (n=1). Conclusion:Celiac disease may accompany many different neurological conditions. These disorders can share some symptoms such as associated anemia, short stature, and chronic gastrointestinal complaints and the diagnosis of celiac disease may be delayed among patients with neurological disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Celiac Disease and Associated Neurological Conditions

IŞIKAY¹,

HIZLI²

2015

Turkish J Pediatr Dis

View full text Add to dashboard Cite

show abstract

“…В Иране подобное исследова-ние позволило выявить 2% больных целиакией среди всех детей с мигренью [10]. В ходе проведенного в США ис-следования [11] была установлена высокая распростра-ненность мигрени у взрослых пациентов с воспалитель-ным заболеванием кишечника, глютеновой чувствитель-ностью и целиакией, однако не была дана подробная ха-рактеристика синдрома мигрени у больных целиакией. Одновременно был предложен термин «генетически сен-ситивная нервная система», в соответствии с которым вы-сказано предположение о том, что мигрень, синдром раз-драженного кишечника и целиакия -заболевания-моде-ли этого состояния [12].…”

unclassified

Gluten migraine

Kopishinskaya¹,

Густов²

2015

Z. nevrol. psikhiatr. im. S.S. Korsakova

View full text Add to dashboard Cite

Целиакия -хроническое аутоиммунное генетиче-ское заболевание, которое характеризуется иммунным от-ветом на потребляемый в пищу глютен, содержащийся в зернах пшеницы, ржи, ячменя, в результате чего развива-ются воспаление, атрофия ворсинок и гиперплазия крипт в тонком кишечнике [1]. Частыми проявлениями класси-ческой формы целиакии являются диарея, боль в животе, потеря массы тела, общая слабость. Только у 30% взрос-лых встречается классическая форма целиакии, у осталь-ных 70% наблюдается атипичная форма, для которой ха-рактерны разнообразные экстраинтестинальные проявле-ния. Раньше целиакию считали исключительно глютено-вой энтеропатией, однако сейчас имеется все больше данных о мультисистемном характере заболевания. Не-врологическими проявлениями целиакии являются атак-сия, полинейропатия, деменция, миопатия, эпилепсия и мигрень [2,3]. Цель исследования -изучение распространенности мигрени среди больных целиакией, клинических особенностей синдрома «глютеновая мигрень» и оценка эффективности аглютеновой диеты в ее лечении. Материал и методы. Основную группу составили 200 пациентов с целиакией, группу сравнения -100 больных с рефлюкс-эзофагитом без целиакии. Пациенты заполняли дневник головной боли в течение 3 мес до постановки диагноза мигрени и 6 мес аглютеновой диеты. Результаты. В основной группе синдром мигрени встречался в 4 раза чаще, чем в группе сравнения (48,5%; p<0,001), мигренозные приступы отличались большей частотой (в 2,5 раза выше, р=0,004), но были менее продолжительными (в среднем 8 ч), приступы были менее интенсивными по визуальной аналоговой шкале в процентах (в среднем 55) и с более поздним дебютом, чаще встречались у больных старше 50 лет (р<0,05). На фоне аглютеновой диеты у 1 / 4 пациентов основной группы наблюдалось исчезновение приступов мигрени, у 38% -уменьшение интенсивности и/или их частоты. Установлена четкая ассоциация мигрени и целиакии и показана высокая эффективность аглютеновой диеты в лечении симптомов мигрени. Ключевые слова: мигрень, целиакия, аглютеновая диета.Objective -to study the prevalence of migraine among patients with celiac disease (CD) and clinical features of «gluten migraine» syndrome and to assess the efficacy of gluten diet in its treatment. Material and methods. Authors examined 200 CD patients (main group) and 100 patients with reflux esophagitis and without CD (control group). All patients fulfilled the headache diary during three months before the diagnosis of migraine was made and six months during gluten diet. Results and conclusion. CD group had migraine syndrome four times more often than the control group (48.5%; p<0.001). In CD group migraine attacks were 2.5 times more frequent than in the control group (р=0.004), but the duration of the attacks was less long, 8 hours in average. The migraine attacks measured by the Visual Analog Scale were less intensive, 55% in average, and had a later onset. The attacks were more frequent in CD patients who were older than 50 years old (р<0.05). The attacks disappeared in 25% of patients with migraine syndrome wh...

show abstract

“…This is not only shows in the amount of follow up but also the response to treatment. As per the data representation in Figure 6, the assumptions made for the study are being proven (27,32,39) .…”

mentioning

confidence: 99%

Case Study of Gastro-Oesophageal Reflux Disease (Gerd) v/ S Migraine: Do They Mingle or Is It a Myth.

MS¹

2017

IJAR

View full text Add to dashboard Cite

Introduction: Over the years, there has been a dilemma regarding arriving at a diagnosis for headache pertaining to its variety of causes. One of the most common overlooked cause in the present day scenario for headache is GERD and Migraine. On day to day basis, we come across varied patient symptomatology which has indeed made us give a second thought to prescribe on management. Aim and Objective: To study if GERD and Migraine actually co-exist or they have a separate root cause for headache and also how change in lifestyle has an impact on health. Methodology: A study of random sample of 450 patients was conducted based on clinical evaluation for diagnosis and conservative management for the same was advised emphasising particularly on lifestyle modification. Results:The results drawn were compared by tabulating them into 3 groups with the two conditions taken as a separate entity and third when the two being mingled to conclude if interlink exists between the two conditions or purely is it a myth. Conclusion: Intermingling of GERD and Migraine was noted predominantly in our study rather than their separate existence.

show abstract

Prevalence of Migraine in Patients With Celiac Disease and Inflammatory Bowel Disease

Abstract: Migraine was more prevalent in celiac disease and IBD subjects than in controls. Future studies should include screening migraine patients for celiac disease and assessing the effects of gluten-free diet on migraines in celiac disease.

Cited by 123 publications

References 41 publications

Celiac Disease and Associated Neurological Conditions

Celiac Disease and Associated Neurological Conditions

Gluten migraine

Case Study of Gastro-Oesophageal Reflux Disease (Gerd) v/ S Migraine: Do They Mingle or Is It a Myth.

Contact Info

Product

Resources

About