Prevalence of obstructive sleep apnoea following head and neck cancer treatment: A cross-sectional study

Nesse, Willem; Hoekema, Aarnoud; Stegenga, Boudewijn; Hoeven, Johannes H. van der; Bont, Lambert G.M. de; Roodenburg, Jan

doi:10.1016/j.oraloncology.2005.06.022

Cited by 55 publications

(47 citation statements)

References 21 publications

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“…In a study of 16 tongue-cancer patients, only one was diagnosed with OSA. 17 The prevalence of OSA of tongue-carcinoma patients after treatment in this study was also much higher than that in studies conducted in other countries.…”

Section: Discussioncontrasting

confidence: 59%

“…16 Narrowing of the upper airway as a result of surgery may be due to immobile and bulky flap reconstructions, altered suprahyoid and pharyngeal musculature, soft-tissue fibrosis, etc. 17 Theoretically, radiotherapy may have both beneficial and detrimental effects on the upper airway. In some cases, radiotherapy may cause tissue scarring that contracts and narrows the airway, thereby causing OSA to develop.…”

mentioning

confidence: 99%

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Prevalence of obstructive sleep apnea in patients with squamous cell carcinoma of the tongue following ablation surgery

Chan

Chou

Lee

et al. 2012

Journal of Dental Sciences

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Background/purpose: The purpose of this study was to determine the prevalence of obstructive sleep apnea (OSA) in patients with squamous cell carcinoma (SSC) of the tongue after primary surgical resection and to correlate the presence of OSA with the occurrence of obstructive apnea in this patient population. Materials and methods: This was a retrospective study of 26 Taiwanese patients, 24 males and two females, aged 37e71 years, after surgical resection of SSC of the tongue. Patients who had a follow-up after treatment of 6 months to 11 years were eligible for inclusion. During the posttreatment period, the occurrence of OSA was determined in these patients. Overnight polysomnography (PSG) was used to determine the apneaehypopnea index (AHI). Patients were considered to have OSA if the AHI value was >5. Results: Patients with an AHI value of <5 showed a mean body mass index (BMI) of 22.8 kg/m 2 , while those with an AHI value of >5 showed a mean BMI of 28.3 kg/m 2 . The BMI distribution between patients with AHI value of <5 and those with AHI values of >5 was statistically significant (P Z 0.018). Using the definition of clinically significant sleep apnea as AHI > 5, 14 of 26 patients (53.85%) had clinical OSA. The OSA and non-OSA groups showed no statistical significance in terms of age, tumor size, tongue ablation, neck dissection [method?], or wound reconstruction methods. Conclusion: Incidence of OSA in the patient population with SSC of the tongue was found to be significantly higher than that in the general population. The limitations of this study were the Journal of Dental Sciences (2012) 7, 245e249 relatively small patient sample size and no presurgical PSG record being obtained from the patients to compare the sleep quality before and after cancer therapy.

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Section: Discussioncontrasting

confidence: 59%

mentioning

confidence: 99%

Prevalence of obstructive sleep apnea in patients with squamous cell carcinoma of the tongue following ablation surgery

Chan

Chou

Lee

et al. 2012

Journal of Dental Sciences

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“…Several previous reports [ 43 , 44 ] have described OSA in cancer populations, especially patients with head and neck cancers. Nesse et al [ 45 ] screened 33 patients with a history of surgical and/or radiation treatment for head and neck cancers during follow-up visits that ranged from 6 months to 5 years after treatment. Ten of the 33 (30%) reported symptoms consistent with OSA.…”

Section: Other Sleep Disordersmentioning

confidence: 99%

Sleep and cancer: Recent developments

Sateia

Lang²

2008

Curr Oncol Rep

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During the past decade, the critical role of sleep in health and disease has been underscored by research that further defines the relationship between sleep and myriad physiologic and psychological functions as well as quality of life. For many years, there was little exploration of the significance of sleep and sleep disorders in cancer patients; however, the past decade has seen a steady growth of inquiry in this area. These investigations have demonstrated the high frequency and significance of sleep disturbance as a symptom in cancer patients. They have also explored the complex interaction between sleep and other common cancer symptoms, most notably fatigue, depression, and pain, and have identified risk factors associated with the development of sleep problems in this population. Although treatment studies lag behind, reports of effective psychological and behavioral interventions for insomnia in cancer patients are increasing. Several studies are addressing pharmacotherapeutic intervention for hot flashes as a potential source of sleep disturbance. Other sleep disorders, most notably obstructive sleep apnea, also occur with some regularity in cancer patients.

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“…The intermittent hypoxia, consequent to obstruction, and the sleep fragmentation lead to an increased cardiovascular risk and daytime sleepiness. Some authors reported a high prevalence of OSAS in patients treated for head and neck cancer, underlining the importance to screen them to increase their quality of life [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

Two Cases of Severe Obstructive Sleep Apnea Induced by Neck Radiotherapy Treated with an Oral Device

Piccin

Sorrenti

Milano

2015

J. Maxillofac. Oral Surg.

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Prevalence of obstructive sleep apnoea following head and neck cancer treatment: A cross-sectional study

Cited by 55 publications

References 21 publications

Prevalence of obstructive sleep apnea in patients with squamous cell carcinoma of the tongue following ablation surgery

Prevalence of obstructive sleep apnea in patients with squamous cell carcinoma of the tongue following ablation surgery

Sleep and cancer: Recent developments

Two Cases of Severe Obstructive Sleep Apnea Induced by Neck Radiotherapy Treated with an Oral Device

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