Prevalence of Tako-Tsubo Syndrome among patients with suspicion of acute coronary syndrome referred to our centre

Facciorusso, Antonio; Vigna, Carlo; Amico, Cesare; Lanna, Pompeo; Troiano, Giovanni; Stanislao, Mario; Valle, Guido; Santoro, Tiberio; Fanelli, Raffaele

doi:10.1016/j.ijcard.2007.12.104

Cited by 13 publications

(4 citation statements)

References 15 publications

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“…Beyond the Mayo Clinic criteria, at least others six features make to think to CA caused by SC in our patient: 1 There was a physical stress event in our case, that usually is found in SC [2]. 2 CA caused by VA are described in SC [3,4] and we believe the mechanism of CA, in our case, could be a VA. 3 The SC usually occurs in postmenopausal women [2,5], but has been described still in premenopausal period [6,7]. 4 The development, in our case, of diffuse T-wave inversion that involves most leads and prolongation of the QT interval is found in SC [2].…”

Section: Discussionmentioning

confidence: 53%

Cardiac Arrest caused by Barlow's Syndrome or by Stress Cardiomyopathy?

Facciorusso

Amico

Vigna

et al. 2010

International Journal of Cardiology

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Section: Discussionmentioning

confidence: 53%

Cardiac Arrest caused by Barlow's Syndrome or by Stress Cardiomyopathy?

Facciorusso

Amico

Vigna

et al. 2010

International Journal of Cardiology

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“…The prevalence of the disease is unknown. However, since TTC has become more widely recognized and more specific criteria have been established, higher prevalence rates have been reported [4]. …”

Section: Discussionmentioning

confidence: 99%

Takotsubo Cardiomyopathy: A Cardiac Syndrome Mimicking Acute Myocardial Infarction in a Liver Transplant Recipient

et al. 2011

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Takotsubo cardiomyopathy (TTC) is a rare clinical syndrome defined as a profound but reversible left ventricular dysfunction in the absence of coronary artery disease. We describe the clinical features and management of TC manifesting in the postoperative period in a patient undergoing liver transplantation. Two days after surgery, the patient developed clinical features of acute myocardial infarction. Ecochardiography revealed hypokinesis of the left ventricle. Coronary angiography revealed normal arteries without any stenosis or obstruction. The patient required vasopressor and inotropic support. The placement of intra-aortic balloon pump had a beneficial effect on the management of heart failure. The patient had a complete recovery of cardiac function 40 days after surgery. TC is a possible occurrence after liver transplant. Awareness of this condition is essential as early diagnosis and prompt management can save the patient’s life.

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“…Segundo a mais recente, proposta pela Clínica Mayo (EUA) e pelo Takotsubo Cardiomyopathy Study Group (Japão), a Cardiomiopatia de Takotsubo pode ser definida pelos seguintes critérios: (1) hipocinesia, discinesia ou acinesia transitória dos segmentos médios e apicais do ventrículo esquerdo (VE) com ou sem envolvimento apical, com alterações da contratilidade da área de vascularização correspondente a mais do que uma artéria coronária; (2) ausência de doença coronariana obstrutiva ou angiografia que evidencie uma ruptura de placa arteriosclerótica; (3) alterações eletrocardiográficas de novo (supradesnivelamento de ST e/ou inversão das ondas T) ou aumento discreto dos níveis séricos de troponina; (4) ausência de feocromocitoma ou miocardite. Vale ressaltar que a diretriz japonesa designa o balonamento apical secundário, acidentes cerebrovasculares e feocromocitomas como "Disfunções MiocárdicasTakotsubo-like" 7 . A fisiopatologia da doença ainda não foi totalmente elucidada, no entanto, várias hipóteses concordam que o excesso de catecolaminas (gerado por atuação medicamentosa ou, principalmente, situações de estresse) tenha um papel decisivo na patogênese da doença.…”

Section: Introductionunclassified

Estudo clínico-epidemiológico da cardiomiopatia de Takotsubo em um hospital de referência em Fortaleza, Ceará, Brasil

Pereira¹,

Rensi²,

Gómez³

et al. 2017

Arch Health Invest

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ResumoA Cardiomiopatia de Takotsubo (CMT), também denominada Síndrome do Coração Partido, constitui uma entidade nosológica própria e uma causa rara de disfunção transitória do ventrículo esquerdo, na ausência de doença coronária significativa. O propósito do presente trabalho foi analisar as características clínico-epidemiológicas dos casos internados por Cardiomiopatia de Takotsubo no Hospital de Messejana (HM), explorando a possível relação entre um estressor específico e o desenvolvimento da CMT. Trata-se de estudo epidemiológico descritivo, prospectivo, com eixo transversal analítico no qual foram observados prospectivamente todos os prontuários de pacientes com diagnóstico presumido de IAM e circunscreveu-se o tamanho da amostra aos casos com diagnóstico confirmado de Cardiomiopatia de Takotsubo, segundo os critérios de 2004 de Bybee et al. Os resultados apontaram que de 1147 prontuários analisados, entre janeiro e agosto de 2016, 9 pacientes satisfizeram os critérios para o diagnóstico de CMT. Oito (88,8%) pacientes eram do sexo feminino, com idade média de 60,7 anos. Dos pacientes analisados apenas 4 (44,4%) tinham estressores emocionais associados. Identificou-se forte associação entre idade e fator estressor prévio (r=0,799). Concluiu-se que a Cardiomiopatia de Takotsubo deve sempre ser considerada no diagnóstico diferencial da Síndrome coronariana aguda, mesmo os sintomas não tendo sido precipitados por intenso estresse emocional. Descritores: Cardiomiopatia de Takotsubo; Disfunção Ventricular; Miocárdio Atordoado. AbstractTakotsubo Cardiomyopathy (TCM), also called the Broken Heart Syndrome, constitutes a nosologic entity of its own and is a rare cause of transient left ventricular dysfunction in the absence of significant coronary disease. The objective of this paper was analyzed the clinical and epidemiological characteristics of patients hospitalized for Takotsubo Cardiomyopathy at the Hospital de Messejana (HM), exploring the possible relationship between a specific stressor and the development of Takotsubo Cardiomyopathy. This is a descriptive, prospective epidemiological study with an analytical transversal axis in which all medical records of patients with a suspected AMI diagnosis were prospectively analyzed and the sample size circumscribed to cases with a confirmed diagnosis of Takotsubo Cardiomyopathy, according to the criteria of Bybee et al. at 2004. The results pointed that from 1147 patient charts analyzed, between January and August 2016, 9 patients met the criteria for the diagnosis of CMT. Eight (88.8%) patients were female, with a mean age of 60.7 years. Of the patients analyzed, only 4 (44.4%) had associated emotional stressors. It was identified a strong association between age and previous stressor (r = 0.799). It is concluded that Takotsubo Cardiomyopathy should always be considered in the differential diagnosis of acute coronary syndrome, even if the symptoms were not precipitated by intense emotional stress. Descriptors: Takotsubo Cardiomyopathy; Ventricular Dysfunction; Myoc...

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Prevalence of Tako-Tsubo Syndrome among patients with suspicion of acute coronary syndrome referred to our centre

Cited by 13 publications

References 15 publications

Cardiac Arrest caused by Barlow's Syndrome or by Stress Cardiomyopathy?

Cardiac Arrest caused by Barlow's Syndrome or by Stress Cardiomyopathy?

Takotsubo Cardiomyopathy: A Cardiac Syndrome Mimicking Acute Myocardial Infarction in a Liver Transplant Recipient

Estudo clínico-epidemiológico da cardiomiopatia de Takotsubo em um hospital de referência em Fortaleza, Ceará, Brasil

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