Prevalence of women breast cancer

Abstract

Breast cancer, the most frequent disease in women worldwide, represents a significant public health concern on a global scale. Breast cancer was the most frequent type of cancer among Iraqi women in 2018, accounting for the highest percentage of malignant tumors in women. Breast cancer is a set of physiological and molecular heterogeneous diseases that begin in the breast. Advanced breast cancer with distant organ metastases is considered incurable with current therapies. Aside from new treatment improvements, the next global challenge in breast cancer care is equal worldwide access to therapeutic advances. The incidence of breast cancer continues to rise in every part of the world. Despite advances in its identification and treatment, which have resulted in lower mortality rates, it appears vital to seek out new therapeutic approaches, predictive and prognostic indicators. The article provides a literature review of breast carcinoma, a condition that affects women worldwide. As a result, women should be aware of the disease's course, the importance of regular screenings for early detection of breast cancer, and the best treatment options.

LINC00467 enhanced the proliferative, migratory and invasive ability of breast cancer cells by targeting miR-18a/b-5p/MAPK4 axis

“…LncRNA-UCA1 improved cell proliferation in esophageal cancer as a ceRNA of Sox4 (28). SNHG5 regulated the proliferation and migration of gastric cancer cells via miR-32/KLF4 axis (29)(30)(31)(32). Based on this theory, we hypothesized that LINC00467 may also function as ceRNA in BC.…”

High expression of VTA1 is an adverse prognostic factor in lung adenocarcinoma

“…By similarities, VTA1 is also implicated in EGFR sorting and downregulation. The expression of VTA1 in LUAD and its prognostic significance, however, are yet unknown [23,24].…”

Pan-cancer analysis reveals a regulatory pattern of anoikis in human cancers

“…The anti-tumor impact of anoikis is undeniable, and prior research has shown that it is still fundamentally a sort of apoptosis. Anoikis resistance is one of the critical elements that cannot be disregarded in the evolution of cancer, according to an increasing number of studies [40][41][42][43][44][45][46]. According to our GSVA research, oxidative stress, EMT, and energy metabolism make up the majority of anoikis resistance.…”