Preventive efficacy of clinoptilolite in broilers during chronic aflatoxin (50 and 100ppb) exposure

Oguz, H.; Kurtoğlu, V.; Çoşkun, Behiç

doi:10.1053/rvsc.2000.0417

Cited by 59 publications

(49 citation statements)

References 24 publications

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“…The increase in mortality rate due to aflatoxicosis at 35 days of age and in the entire period of experiment of this study was in agreement with that reported by Pasha et al (2007). The increase of mortality rate due to aflatoxicosis at 35 days of age of this study may be attributed to reducing disease resistance, the gradually increase of toxic effects (Oguz et al, 2000), or, severely inhibiting the immune system of the birds (Pasha et al, 2007). The significant decrease in mortality rate due 0.2% Humate or 0.5% HSCAS supplementation, in the present study, was in agreement with previous investigations in broiler chicks fed aflatoxin contaminated diets with Humate or HSCAS (Jansen van Rensburg,et al, 2006 andHassan et al, 2009).…”

Section: Growth Performance Parameterssupporting

confidence: 92%

Evaluation of Antimycotoxin Effects of Humate and Hydrated Sodium Calcium Aluminosilicate on Broilers Toxicated with Aflatoxin

Tawfeek¹,

Hassan²,

Eid³

2017

AJVS

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Key words:aflatoxin, broiler, adsorbent compounds, detoxificationThe objective of this study was to investigate the protective effect of dietary natural sorbent-Humate (0.2%) and Hydrated sodium calcium aluminosilicate (HSCAS) (0.5%) on the prevention of aflatoxin (AF) toxicity in the broiler chicken 7-35 days of age. Two hundred and forty broiler chicks were randomly divided into four treatment groups of 4 replicates (each contained 15 chicks). While chicks in group 1 were fed a basal diet free of toxin (control), group 2 chicks were fed a basal diet contaminated with 1ppm AF, the other two groups 3 and 4 were fed contaminated basal diet supplemented with 0.2% Biofarm® Dry humate, and 0.5% HSCAS, respectively. Parameters evaluated were growth performance, some serum constituents, some organs weight, and immune response to Newcastle disease and infectious bursal disease. The results showed that, Aflatoxin (1 ppm/kg) significantly reduced feed intake, weight gain and feed efficiency. Further aflatoxin increased the relative weights of liver, kidney, gizzard and spleen, while the relative weights of thymus and bursa of Fabricius were decreased by AF. Aflatoxin toxin also reduced antibody titres against Newcastle disease and infectious bursal disease. Modified 0.2% Humate significantly (P ≤ 0.05) improved body weight, feed intake, decreased relative organ weights and improved antibody titres, bursa of Fabricius and thymus weights. Hydrated sodium calcium aluminosilicate (0.5%) showed improvement against AF. The results of our experiment showed that 0.2% Humate and 0.5% HSCAS has a positive effect on the growth of broilers. And it could have been a suitable natural supplement for growing broilers against the adverse effects of aflatoxins.

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Section: Growth Performance Parameterssupporting

confidence: 92%

Evaluation of Antimycotoxin Effects of Humate and Hydrated Sodium Calcium Aluminosilicate on Broilers Toxicated with Aflatoxin

Tawfeek¹,

Hassan²,

Eid³

2017

AJVS

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“…Twenty AFs have already been identified, with aflatoxin B 1 (AFB 1 ) being one of the most common and toxic compounds present in avian feed (Hussein & Brasel 2001). The toxicity of AFs in broilers has been widely investigated for their carcinogenic, mutagenic, teratogenic and growth inhibitory effects (Oğuz et al 2000;Sur & Celik 2003). Animals that consume AF-contaminated feed develop various health problems, including growth retardation, reduction in feed efficiency, and liver and kidney damage (Bintvihok 2002).…”

Section: Introductionmentioning

confidence: 99%

Effect of monogastric and ruminant gastrointestinal conditions onin vitroaflatoxin B₁adsorption ability by a montmorillonite

Magnoli

Alonso

Cavaglieri

et al. 2013

Food Additives & Contaminants: Part A

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The main objective of this study was to evaluate the interference of environment components on the in vitro evaluation of aflatoxin B₁ adsorption capacity of sodium bentonite under simulated gastrointestinal conditions of monogastric and ruminant animals. Sodium bentonite showed a high aflatoxin B₁ affinity with all of the assays. Langmuir or sigmoid isotherms were found in different assays. Both the affinities and the surface excesses at monolayer saturation were affected by the buffer components. The specific influence of ions in each buffer solution was investigated. A significant decrease in the surface excess at monolayer saturation was observed under ionic strength control. A change in the isotherm shape from sigmoidal to Langmuir was observed with the increase in the sodium chloride concentration. This was attributed to the decrease in the importance of lateral interaction between adsorbed toxin molecules compared with surface-molecules interactions under a high salt coverage. The presence of rumen fluid components in the adsorption environment decreased the aflatoxin B₁ maximum adsorption capacity of sodium bentonite. Despite the high affinity of this adsorbent to capture aflatoxin B₁, different substances present in the environment could affect the adsorption capacity, at least at low toxin concentrations that mimic chronic exposure. The environment of the gastrointestinal tract, in either monogastric or ruminant animals, affect in vivo aflatoxin B₁ adsorption by sodium bentonite and should be taken into account when an in vitro performance evaluation is done.

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“…[2] . Different approaches such as irradiation, mold inhibitors, dietary absorbents, ammoniation and ozone degradation were applied to reduce food and feed contamination by aflatoxins [3,4] . Unfortunately, most of these methods are expensive and only partially effective.…”

Section: öZetmentioning

confidence: 99%

Broyler Piliçlerde Rasyona Katılan Geyikotu Esansiyel Yağının Aflatoksin B1 Toksisitesinin Azaltılmasındaki Etkinliği

Sadeghi¹,

Mohamadi-Saei²,

Ahmadvand³

2014

Kafkas Univ Vet Fak Derg

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The aim of this study was to evaluate the capability of savory essential oil in counteracting the deleterious effects of aflatoxin B 1 (AFB 1 ) on growth performance, serum biochemistry, and humoral immune responses in broiler chickens fed 42 days of age. At a 2 2 factorial arrangement in completely randomized design, 300 day-old broiler chicks were assigned to four treatments with five replicates of 15 birds. Chickens were fed the basal diet up to day 7 of age and then fed the experimental diets. The dietary treatments involved of 0 and 0.5 mg of AFB1/kg with or without 500 mg of savory/kg dry matter. The addition of aflatoxin to diet decreased (P<0.05) the weight gain and feed intake and resulted in a poor feed conversion ratio. Birds in the AFB 1 group had lower level of albumin, but higher levels of creatinine and liver enzymes in the serum as compared with the control group. The addition of savory to the contaminated diet diminished (P<0.05) the inhibitory effects of dietary AFB 1 on the growth performance and the level of liver enzymes in serum. The addition of aflatoxin to diet caused a decrease and savory supplementation caused an increase in antibody titer against the Newcastle virus, and interaction among the factors was differ (P<0.05). The main effects and interaction on antibody titer against influenza virus were not differ (P>0.05). The addition of savory reduced the adverse effects of aflatoxin on growth performance and provided slight positive effect on serum biochemistry and humoral immune responses in broilers exposed aflatoxin. Keywords: Aflatoxin, Broiler, Savory, Protection Broyler Piliçlerde Rasyona Katılan Geyikotu Esansiyel YağınınAflatoksin B 1 Toksisitesinin Azaltılmasındaki Etkinliği ÖzetBu çalışma, 42 gün süreyle beslenen broyler piliçlerde yeme katılan geyioktu esansiyel yağının, aflatoksin B 1 (AFB 1 )'in büyüme performansı, serum biyokimyası ve hümoral immün yanıtlar üzerine olan zararlı etkilerini yoketme kapasitesinin değerlendirilmesi amacıyla yapıldı. Randomize tasarım ile 2 2 faktöryel düzenlemede, 300 günlük broyler piliçler 15 kanatlı içeren beş tekrarlı dört tedavi grubu olacak şekilde ayarlandı. Piliçler 7. güne kadar temel rasyon ve daha sonra deneysel diyet ile beslendi. Besinsel tedaviler 500 mg kuru madde olarak geyioktu/kg içeren veya içermeyen 0 ve 0.5 mg AFB 1 /kg'dan oluştu. Rasyona aflatoksin eklenmesi ağırlık kazancını ve yem tüketimini azaltırken (P<0.05) zayıf bir yem dönüşüm oranıyla (poor feed conversion ratio) sonuçlandı. AFB 1 grubundaki kanatlıların kontrol grubuyla kıyaslandığınıda düşük albumin düzeyine, fakat yüksek serum kreatin ve karaciğer enzimleri düzeyine sahip olduğu gözlemlendi. Kontamine rasyona geyioktu ilavesinin besinsel AFB1'in büyüme performansı ve serumdaki karaciğer enzim seviyesi üzerindeki inhibitör etkilerini azalttığı (P<0.05) belirlendi. Newcastle virüsüne karşı gelişen antikor titresinin rasyona aflatoksin ilavesi ile azaldığı ve geyioktu ilavesi ile arttığı ve faktörler arası etkileşimin farklı (P<0.05) olduğu gözlemlendi. İnfluen...

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Preventive efficacy of clinoptilolite in broilers during chronic aflatoxin (50 and 100ppb) exposure

Cited by 59 publications

References 24 publications

Evaluation of Antimycotoxin Effects of Humate and Hydrated Sodium Calcium Aluminosilicate on Broilers Toxicated with Aflatoxin

Evaluation of Antimycotoxin Effects of Humate and Hydrated Sodium Calcium Aluminosilicate on Broilers Toxicated with Aflatoxin

Effect of monogastric and ruminant gastrointestinal conditions onin vitroaflatoxin B₁adsorption ability by a montmorillonite

Broyler Piliçlerde Rasyona Katılan Geyikotu Esansiyel Yağının Aflatoksin B1 Toksisitesinin Azaltılmasındaki Etkinliği

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Preventive efficacy of clinoptilolite in broilers during chronic aflatoxin (50 and 100ppb) exposure

Cited by 59 publications

References 24 publications

Evaluation of Antimycotoxin Effects of Humate and Hydrated Sodium Calcium Aluminosilicate on Broilers Toxicated with Aflatoxin

Evaluation of Antimycotoxin Effects of Humate and Hydrated Sodium Calcium Aluminosilicate on Broilers Toxicated with Aflatoxin

Effect of monogastric and ruminant gastrointestinal conditions onin vitroaflatoxin B1adsorption ability by a montmorillonite

Broyler Piliçlerde Rasyona Katılan Geyikotu Esansiyel Yağının Aflatoksin B1 Toksisitesinin Azaltılmasındaki Etkinliği

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Effect of monogastric and ruminant gastrointestinal conditions onin vitroaflatoxin B₁adsorption ability by a montmorillonite