2013
DOI: 10.3892/ol.2013.1708
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Primary adenocarcinoma of the rete testis: A case report and review of the literature

Abstract: Primary adenocarcinoma of the rete testis is an extremely rare extratesticular neoplasm. Due to its low occurrence and the scarcity of data, sonographic characteristics of adenocarcinoma of the rete testis are still poorly defined. A 46-year-old male complained of swelling and pain in the right side of the scrotum. No associated symptoms were observed. Anti-tuberculosis chemotherapy yielded no response. Postoperative pathology revealed a diagnosis of poorly-differentiated adenocarcinoma of the rete testis. Usi… Show more

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Cited by 13 publications
(9 citation statements)
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“…The absence of large uniform cells with dis-cohesion mixed with lymphocytes helps distinguish seminoma, the most common neoplasm of the testis [ 4 ]. However, metastatic adenocarcinoma and primary adenocarcinoma of the urinary bladder might be indistinguishable because they are fairly similar to their counterparts in organs such as the stomach, colon, and prostate [ 3 , 5 ]. When encountered with this diagnostic challenge, physicians can use certain clinical and morphological characteristics to differentiate metastatic lesions.…”
Section: Discussionmentioning
confidence: 99%
“…The absence of large uniform cells with dis-cohesion mixed with lymphocytes helps distinguish seminoma, the most common neoplasm of the testis [ 4 ]. However, metastatic adenocarcinoma and primary adenocarcinoma of the urinary bladder might be indistinguishable because they are fairly similar to their counterparts in organs such as the stomach, colon, and prostate [ 3 , 5 ]. When encountered with this diagnostic challenge, physicians can use certain clinical and morphological characteristics to differentiate metastatic lesions.…”
Section: Discussionmentioning
confidence: 99%
“…Adenomatoid tumors are rare but account for about 30% of paratesticular tumors. It is most frequently located in the epididymis, less frequently in the spermatic cord, ejaculatory duct, testis parenchyma, prostate and adrenal gland (4) . It is common in 3 rd -4 th decades.…”
Section: Discussionmentioning
confidence: 99%
“…Eosinophilic cytoplasm and cords are important in the differential diagnosis of Sertoli cell and Leydig cell tumors. These tumors show immunoreactivity with mesothelial markers such as Calretinin and D2-40 (4,5) . One of our cases was adenomatoid tumor consisting of cuboidal cells, forming solid groups and cords.…”
Section: Discussionmentioning
confidence: 99%
“…The majority of symptoms in patients are a scrotal mass with diffuse enlargement of the testis. However, it is difficult to make a differential diagnosis with other testicular lesions, as rete testis adenocarcinoma also invariably presents with epididymitis, hydrocele, inflammatory lumps, or inguinal hernia (6,7). This patient also complained of the same thing with significant testicular enlargement within a period of 3 months.…”
Section: Case Reportmentioning
confidence: 91%
“…Although rare, neoplasms arise and typically are both benign cystadenoma or malignant cystadenocarcinoma (5). Adenocarcinoma of the rete testis is a rare, highly aggressive tumor originating from the non-spermatogenic epithelium of the intratesticular excretory ducts (6). About 72 cases reported in the English language literature since its first description by Feek and Hunter in 1945.…”
Section: Case Reportmentioning
confidence: 99%