Primary and metastatic rhabdomyosarcoma in the breast: report of two pediatric cases

Binokay, Figen; Soyupak, Süreyya; İnal, Mehmet; Çeliktaş, Medih; Akgül, Erol; Aksungur, Erol

doi:10.1016/s0720-048x(03)00041-x

Cited by 33 publications

(20 citation statements)

References 9 publications

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“…All patients with breast metastasis from RMS also had an alveolar histology and were adolescent girls [7]. The primary breast RMS lesions were bilateral in 2 cases [14,21], and regional lymph node involvement was present in 4 patients [8,10,11,12]. RMS cases with bilateral breast metastasis have been reported to account for less than 25%, while metastatic lymph nodes have been encountered in 25-58% [24,7].…”

Section: Discussionmentioning

confidence: 99%

“…Breast involvement is very rare, both as a primary or as a metastatic site [7]. Only a few cases of primary RMS of the breast in children have been reported in the literature (table 1) [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22]. Due to the extremely rare incidence of primary breast RMS, radiologic imaging features have yet to be clearly defined.…”

Section: Introductionmentioning

confidence: 99%

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Primary Rhabdomyosarcoma of the Breast: Imaging Findings and Literature Review

et al. 2018

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Background: Primary breast rhabdomyosarcoma (RMS) can occur in children. There is a lack of knowledge regarding radiologic findings and added diffusion-weighted magnetic resonance imaging (MRI) features of RMS in the literature. Case Report: A 12-year-old girl was diagnosed with primary alveolar RMS of the breast. Gray scale ultrasound revealed posterior acoustic enhancement behind a well-circumscribed, multilobulated hypoechoic mass. Doppler ultrasound revealed increased peripheral and central vascularity. Hypointense septations on T2-weighted image exhibiting more enhancement than the stroma on late gadolinium-enhanced images were striking within a hyperintense mass. A hyperintense hemorrhagic focus on T1-weighted image was present in the absence of any necrosis. Avid enhancement on early postcontrast images proceeding from the periphery to the center was depicted. Conclusion: A rapidly enlarging mass with an echogenic peripheral rim together with posterior acoustic enhancement on gray scale ultrasound, intense vascularity on Doppler ultrasound, axillary lymphadenopathy, and satellite nodules on MRI should raise suspicion. Enhancing central and peripheral septations are suggestive of RMS. Dynamic contrast-enhanced MRI in suspected cases can provide valuable data in the differential diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Primary Rhabdomyosarcoma of the Breast: Imaging Findings and Literature Review

et al. 2018

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“…In adolescents, both these entities are known to occur and their differentiation is important. This may be predicted reasonably well by their radiological appearance [4].…”

Section: Discussionmentioning

confidence: 55%

A case of primary rhabdomyosarcoma of the breast

et al. 2007

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“…The primary tumour may arise from the nasopharynx, body or extremities (Binokay et al 2003). Bilateral involvement is seen as much as 30% of cases.…”

Section: Metastasesmentioning

confidence: 99%